Find Copa Airlines flights to Santa Cruz (VVI) from COP 1.669.686*

Promo Code

Restrictions apply; please see Terms & Conditions.

Fares for flights to Santa Cruz through the Hub of the Americas®,in Panama City

COP
sort
keyboard_arrow_down

Cali (CLO)to

Santa Cruz (VVI)
Nov 09, 2026 - Nov 14, 2026
From
COP 1.666.386
Viewed 10 hours ago
Round trip
Economy

Pereira (PEI)to

Santa Cruz (VVI)
Oct 22, 2026 - Oct 27, 2026
From
COP 1.669.686
Viewed 1 day ago
Round trip
Economy

Medellin (MDE)to

Santa Cruz (VVI)
Oct 21, 2026 - Oct 29, 2026
From
COP 1.698.434
Viewed 1 day ago
Round trip
Economy

Santa Marta (SMR)to

Santa Cruz (VVI)
Jul 04, 2027 - Aug 08, 2027
From
COP 2.598.608
Viewed 1 day ago
Round trip
Economy

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Plan your next trip to Santa Cruz with these low fares

COP

Medellin (MDE)to

Santa Cruz (VVI)
Apr 05, 2027 - Apr 09, 2027

Round trip

Economy

From
COP 1.698.434
Viewed 22 hours ago

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Fly to Santa Cruz with Copa Air

Santa Cruz receives a third of Bolivia's tourists, attracted by its cultural capital and its entertainment and relaxation activities. Copa Airlines offers flights to Santa Cruz from different parts of the Americas.

What to visit in Santa Cruz?

  • Colonial footprints: the Plaza 24 de Septiembre, located in the city center, is surrounded by buildings dating back to the colonial era, such as the Metropolitan Cathedral, City Hall, and the Cultural Center.
  • Outings in the fresh air: surrounding the city are numerous nature reserves where you can discover the local flora and fauna, participate in outdoor actives, and relax. The most popular are Las Lomas de Arena Regional Park, the Güembé Biocenter, and the Ivaga Guazú Ecological Park.
  • Go shopping: Santa Cruz boasts malls and shops with domestic and imported items, where you can buy a variety of products and gifts.

Getting around Santa Cruz

The simplest way of touring the city is to use some of the 132 urban bus routes. You can also rent a car or take a taxi to reach more remote destinations. Thanks to the excellent service aboard Copa Airlines, your flight to Santa Cruz will be a very pleasant experience. Book your flight today.

More flight deals