Find Copa Airlines flights to Santa Cruz (VVI) from COP1.648.344*
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Restrictions apply; please see Terms & Conditions.
Fares for flights to Santa Cruz through the Hub of the Americas®,in Panama City
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COP
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Medellin (MDE)to
Santa Cruz (VVI)Jun 09, 2026 - Jun 13, 2026
From
COP1.648.344
Viewed 22 hours ago
Round trip
Economy
Bogota (BOG)to
Santa Cruz (VVI)Apr 16, 2026 - Apr 30, 2026
From
COP1.813.568
Viewed 1 day ago
Round trip
Economy
Cali (CLO)to
Santa Cruz (VVI)Jul 07, 2026 - Jul 14, 2026
From
COP2.062.548
Viewed 1 day ago
Round trip
Economy
Bucaramanga (BGA)to
Santa Cruz (VVI)Jul 08, 2026 - Jul 15, 2026
From
COP2.119.038
Viewed 1 day ago
Round trip
Economy
*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.
Plan your next trip to Santa Cruz with these low fares
flight_takeoff
flight_land
COP
Medellin (MDE)to
Santa Cruz (VVI)
Jun 09, 2026 - Jun 13, 2026
Round trip
Economy
From
COP1.648.344
Viewed 22 hours ago
Bogota (BOG)to
Santa Cruz (VVI)
Aug 21, 2026 - Aug 31, 2026
Round trip
Economy
From
COP1.892.184
Viewed 1 day ago
Cali (CLO)to
Santa Cruz (VVI)
Jul 07, 2026 - Jul 14, 2026
Round trip
Economy
From
COP2.062.548
Viewed 1 day ago
Bucaramanga (BGA)to
Santa Cruz (VVI)
Jul 08, 2026 - Jul 15, 2026
Round trip
Economy
From
COP2.119.038
Viewed 1 day ago
Barranquilla (BAQ)to
Santa Cruz (VVI)
Jul 08, 2026 - Jul 13, 2026
Round trip
Economy
From
COP2.158.868
Viewed 1 day ago
*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.
Fly to Santa Cruz with Copa Air
Santa Cruz receives a third of Bolivia's tourists, attracted by its cultural capital and its entertainment and relaxation activities. Copa Airlines offers flights to Santa Cruz from different parts of the Americas.
What to visit in Santa Cruz?
- Colonial footprints: the Plaza 24 de Septiembre, located in the city center, is surrounded by buildings dating back to the colonial era, such as the Metropolitan Cathedral, City Hall, and the Cultural Center.
- Outings in the fresh air: surrounding the city are numerous nature reserves where you can discover the local flora and fauna, participate in outdoor actives, and relax. The most popular are Las Lomas de Arena Regional Park, the Güembé Biocenter, and the Ivaga Guazú Ecological Park.
- Go shopping: Santa Cruz boasts malls and shops with domestic and imported items, where you can buy a variety of products and gifts.
Getting around Santa Cruz
The simplest way of touring the city is to use some of the 132 urban bus routes. You can also rent a car or take a taxi to reach more remote destinations. Thanks to the excellent service aboard Copa Airlines, your flight to Santa Cruz will be a very pleasant experience. Book your flight today.
