Find Copa Airlines flights to Panama (PTY) from USD267*

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Restrictions apply; please see Terms & Conditions.

Fares for flights to Panama through the Hub of the Americas®,in Panama City

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Guayaquil (GYE)to

Panama (PTY)
May 22, 2026 - May 27, 2026
From
USD272
Viewed 1 day ago
Round trip
Economy

Quito (UIO)to

Panama (PTY)
May 14, 2026 - May 19, 2026
From
USD306
Viewed 16 hours ago
Round trip
Economy

Manta (MEC)to

Panama (PTY)
Mar 13, 2026 - Mar 16, 2026
From
USD267
Viewed 31 minutes ago
Round trip
Economy

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Plan your next trip to Panama with these low fares

USD

Guayaquil (GYE)to

Panama (PTY)
May 22, 2026 - May 27, 2026

Round trip

Economy

From
USD272
Viewed 1 day ago

Quito (UIO)to

Panama (PTY)
May 14, 2026 - May 19, 2026

Round trip

Economy

From
USD306
Viewed 16 hours ago

Manta (MEC)to

Panama (PTY)
May 13, 2026 - May 19, 2026

Round trip

Economy

From
USD286
Viewed 1 day ago

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Fly to Panama with Copa Air

Fly to Panama City, the hub of Copa Airlines flights, and explore the financial capital not only of the country, but of all Central America.

Must-see activities in Panama

  • Some history: the place known as Old Panama was burned down by pirates in 1671 and its ruins contrast with the modern skyline of the buildings that now are in the city center. The Reina Torres de Arauz Anthropological Museum has a stunning and highly valuable collection of pre-Columbian gold jewelry and pottery.
  • The Panama Canal: The best place to observe this impressive piece of human engineering is from the Miraflores Visitors Center, where you can also learn about the history of the canal's construction in an interactive and engaging way for your little ones.
  • A vibrant city: Explore the Casco Viejo area (the old city) on foot to visit art galleries, try local cuisine, or simply take a stroll.

Transportation in Panama

When your flight to Panama arrives the best way to save time and travel comfortably is in a taxi or by booking a tourist shuttle service. You can also rent a car on the copa.com website to discover Panama at your own pace.

Flights from Panama City

To fly from Panama for business or pleasure, the best option is Copa Airlines, which has connections to more than 70 major destinations throughout the Americas.