Find Copa Airlines flights to Panama (PTY) from MXN4,242*

Promo Code

Restrictions apply; please see Terms & Conditions.

Fares for flights to Panama through the Hub of the Americas®,in Panama City

Mexico City (MEX)to

Panama (PTY)
Sep 16, 2025 - Sep 21, 2025
From
MXN4,242
Viewed 10 hours ago
Round trip
Economy

Guadalajara (GDL)to

Panama (PTY)
Oct 19, 2025 - Oct 21, 2025
From
MXN6,839
Viewed 1 day ago
Round trip
Economy

Cancun (CUN)to

Panama (PTY)
Oct 10, 2025 - Oct 24, 2025
From
MXN5,050
Viewed 2 hours ago
Round trip
Economy

Monterrey (MTY)to

Panama (PTY)
Sep 25, 2025 - Sep 28, 2025
From
MXN6,814
Viewed 1 day ago
Round trip
Economy

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Plan your next trip to Panama with these low fares

Mexico City (MEX)to

Panama (PTY)
Oct 09, 2025 - Oct 15, 2025

Round trip

Economy

From
MXN5,266
Viewed 6 minutes ago

Guadalajara (GDL)to

Panama (PTY)
Oct 19, 2025 - Oct 21, 2025

Round trip

Economy

From
MXN6,839
Viewed 1 day ago

Cancun (CUN)to

Panama (PTY)
Oct 10, 2025 - Oct 24, 2025

Round trip

Economy

From
MXN5,050
Viewed 2 hours ago

Monterrey (MTY)to

Panama (PTY)
Sep 25, 2025 - Sep 28, 2025

Round trip

Economy

From
MXN6,814
Viewed 1 day ago

Felipe Angeles, Mexico City (NLU)to

Panama (PTY)
Nov 01, 2025 - Nov 11, 2025

Round trip

Economy

From
MXN5,303
Viewed 11 hours ago

San José del Cabo (SJD)to

Panama (PTY)
Dec 18, 2025 - Dec 29, 2025

Round trip

Economy

From
MXN5,843
Viewed 14 hours ago

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Fly to Panama with Copa Air

Fly to Panama City, the hub of Copa Airlines flights, and explore the financial capital not only of the country, but of all Central America.

Must-see activities in Panama

  • Some history: the place known as Old Panama was burned down by pirates in 1671 and its ruins contrast with the modern skyline of the buildings that now are in the city center. The Reina Torres de Arauz Anthropological Museum has a stunning and highly valuable collection of pre-Columbian gold jewelry and pottery.
  • The Panama Canal: The best place to observe this impressive piece of human engineering is from the Miraflores Visitors Center, where you can also learn about the history of the canal's construction in an interactive and engaging way for your little ones.
  • A vibrant city: Explore the Casco Viejo area (the old city) on foot to visit art galleries, try local cuisine, or simply take a stroll.

Transportation in Panama

When your flight to Panama arrives the best way to save time and travel comfortably is in a taxi or by booking a tourist shuttle service. You can also rent a car on the copa.com website to discover Panama at your own pace.

Flights from Panama City

To fly from Panama for business or pleasure, the best option is Copa Airlines, which has connections to more than 70 major destinations throughout the Americas.