Find Copa Airlines flights to Santa Cruz (VVI) from MXN 9,636*
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Restrictions apply; please see Terms & Conditions.
Fares for flights to Santa Cruz through the Hub of the Americas®,in Panama City
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MXN
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Cancun (CUN)to
Santa Cruz (VVI)Aug 24, 2026 - Aug 28, 2026
From
MXNÂ 9,636
Viewed 1 day ago
Round trip
Economy
Mexico City (MEX)to
Santa Cruz (VVI)Aug 24, 2026 - Sep 08, 2026
From
MXNÂ 9,926
Viewed 5 hours ago
Round trip
Economy
Monterrey (MTY)to
Santa Cruz (VVI)Aug 25, 2026 - Sep 08, 2026
From
MXNÂ 10,000
Viewed 5 hours ago
Round trip
Economy
Guadalajara (GDL)to
Santa Cruz (VVI)Mar 01, 2027 - Mar 12, 2027
From
MXNÂ 11,973
Viewed 23 hours ago
Round trip
Economy
*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.
Plan your next trip to Santa Cruz with these low fares
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MXN
Mexico City (MEX)to
Santa Cruz (VVI)
Sep 28, 2026 - Oct 06, 2026
Round trip
Economy
From
MXNÂ 9,928
Viewed 1 day ago
Monterrey (MTY)to
Santa Cruz (VVI)
Nov 13, 2026 - Nov 18, 2026
Round trip
Economy
From
MXNÂ 10,002
Viewed 1 day ago
Guadalajara (GDL)to
Santa Cruz (VVI)
Jan 21, 2027 - Jan 29, 2027
Round trip
Economy
From
MXNÂ 12,414
Viewed 22 hours ago
*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.
Fly to Santa Cruz with Copa Air
Santa Cruz receives a third of Bolivia's tourists, attracted by its cultural capital and its entertainment and relaxation activities. Copa Airlines offers flights to Santa Cruz from different parts of the Americas.
What to visit in Santa Cruz?
- Colonial footprints: the Plaza 24 de Septiembre, located in the city center, is surrounded by buildings dating back to the colonial era, such as the Metropolitan Cathedral, City Hall, and the Cultural Center.
- Outings in the fresh air: surrounding the city are numerous nature reserves where you can discover the local flora and fauna, participate in outdoor actives, and relax. The most popular are Las Lomas de Arena Regional Park, the Güembé Biocenter, and the Ivaga Guazú Ecological Park.
- Go shopping: Santa Cruz boasts malls and shops with domestic and imported items, where you can buy a variety of products and gifts.
Getting around Santa Cruz
The simplest way of touring the city is to use some of the 132 urban bus routes. You can also rent a car or take a taxi to reach more remote destinations. Thanks to the excellent service aboard Copa Airlines, your flight to Santa Cruz will be a very pleasant experience. Book your flight today.
