Find Copa Airlines flights to Santa Cruz (VVI) from MXN9,809*
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Restrictions apply; please see Terms & Conditions.
Fares for flights to Santa Cruz through the Hub of the Americas®,in Panama City
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MXN
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Mexico City (MEX)to
Santa Cruz (VVI)Sep 16, 2026 - Sep 23, 2026
From
MXN9,809
Viewed 22 hours ago
Round trip
Economy
Monterrey (MTY)to
Santa Cruz (VVI)Jun 01, 2026 - Jun 08, 2026
From
MXN10,254
Viewed 23 hours ago
Round trip
Economy
Cancun (CUN)to
Santa Cruz (VVI)Jul 01, 2026 - Jul 26, 2026
From
MXN11,162
Viewed 23 hours ago
Round trip
Economy
Guadalajara (GDL)to
Santa Cruz (VVI)Sep 06, 2026 - Sep 19, 2026
From
MXN12,300
Viewed 9 hours ago
Round trip
Economy
*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.
Plan your next trip to Santa Cruz with these low fares
flight_takeoff
flight_land
MXN
Mexico City (MEX)to
Santa Cruz (VVI)
Sep 16, 2026 - Sep 23, 2026
Round trip
Economy
From
MXN9,809
Viewed 22 hours ago
Monterrey (MTY)to
Santa Cruz (VVI)
Jun 01, 2026 - Jun 08, 2026
Round trip
Economy
From
MXN10,254
Viewed 23 hours ago
Cancun (CUN)to
Santa Cruz (VVI)
Jul 01, 2026 - Jul 26, 2026
Round trip
Economy
From
MXN11,162
Viewed 23 hours ago
Guadalajara (GDL)to
Santa Cruz (VVI)
Sep 06, 2026 - Sep 19, 2026
Round trip
Economy
From
MXN12,300
Viewed 9 hours ago
*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.
Fly to Santa Cruz with Copa Air
Santa Cruz receives a third of Bolivia's tourists, attracted by its cultural capital and its entertainment and relaxation activities. Copa Airlines offers flights to Santa Cruz from different parts of the Americas.
What to visit in Santa Cruz?
- Colonial footprints: the Plaza 24 de Septiembre, located in the city center, is surrounded by buildings dating back to the colonial era, such as the Metropolitan Cathedral, City Hall, and the Cultural Center.
- Outings in the fresh air: surrounding the city are numerous nature reserves where you can discover the local flora and fauna, participate in outdoor actives, and relax. The most popular are Las Lomas de Arena Regional Park, the Güembé Biocenter, and the Ivaga Guazú Ecological Park.
- Go shopping: Santa Cruz boasts malls and shops with domestic and imported items, where you can buy a variety of products and gifts.
Getting around Santa Cruz
The simplest way of touring the city is to use some of the 132 urban bus routes. You can also rent a car or take a taxi to reach more remote destinations. Thanks to the excellent service aboard Copa Airlines, your flight to Santa Cruz will be a very pleasant experience. Book your flight today.
