Find Copa Airlines flights to Santiago de los Caballeros (STI) from MXN5,692*

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Fares for flights to Santiago de los Caballeros through the Hub of the Americas®,in Panama City

MXN

Mexico City (MEX)to

Santiago de los Caballeros (STI)
Apr 09, 2026 - Apr 16, 2026
From
MXN5,692
Viewed 1 day ago
Round trip
Economy

Cancun (CUN)to

Santiago de los Caballeros (STI)
Mar 16, 2026 - Mar 27, 2026
From
MXN7,414
Viewed 6 hours ago
Round trip
Economy

Felipe Angeles, Mexico City (NLU)to

Santiago de los Caballeros (STI)
Aug 23, 2026 - Aug 27, 2026
From
MXN8,457
Viewed 1 day ago
Round trip
Economy

Guadalajara (GDL)to

Santiago de los Caballeros (STI)
Feb 05, 2026 - Feb 16, 2026
From
MXN7,338
Viewed 12 hours ago
Round trip
Economy

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Plan your next trip to Santiago de los Caballeros with these low fares

MXN

Mexico City (MEX)to

Santiago de los Caballeros (STI)
Apr 09, 2026 - Apr 16, 2026

Round trip

Economy

From
MXN5,692
Viewed 1 day ago

Cancun (CUN)to

Santiago de los Caballeros (STI)
Mar 16, 2026 - Mar 27, 2026

Round trip

Economy

From
MXN7,414
Viewed 6 hours ago

Monterrey (MTY)to

Santiago de los Caballeros (STI)
May 18, 2026 - May 23, 2026

Round trip

Economy

From
MXN7,028
Viewed 1 day ago

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Fly to Santiago de los Caballeros with Copa Air

It is also known as the heart city and it is home of baseball teams and clubs that are opened to dance all night long. When you fly to Santiago de los caballeros, leave your trip in Copa Airlines hands and receive the punctuality and convenient services that will make your trip simpler and more pleasant.

What you shouldn’t miss at Santiago de los Caballeros

  • Centro Leon: known as one of the most attractive landmarks. This place has 3 rooms dedicated to Dominican history and nature. Additionally, it has a special area where you can observe the process of rolling tobacco.
  • Night life: the most popular dance clubs are opened until late at night and have enough space for hundreds of people, who dance the most modern Caribbean rhythms.
  • Rhum and tobacco: this city has important tobacco and sugar cane plantations, for which it is now common to find high quality rhum and cigars.

Moving around Santiago de los Caballeros

At Colon Park, you can take a horse-drawn carriage and enjoy this particular experience. You can also choose from collective taxis called conchos, or you can enjoy a private taxi ride. When traveling to Santiago de los Caballeros with Copa Airlines, you may book a car online on copa.com.