Find Copa Airlines flights to Santo Domingo (SDQ) from MXN5,479*
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Restrictions apply; please see Terms & Conditions.
Fares for flights to Santo Domingo through the Hub of the Americas®,in Panama City
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MXN
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Mexico City (MEX)to
Santo Domingo (SDQ)Feb 25, 2026 - Mar 04, 2026
From
MXN5,479
Viewed 6 hours ago
Round trip
Economy
Cancun (CUN)to
Santo Domingo (SDQ)Jun 25, 2026 - Jul 01, 2026
From
MXN6,220
Viewed 8 hours ago
Round trip
Economy
Monterrey (MTY)to
Santo Domingo (SDQ)Mar 14, 2026 - Apr 07, 2026
From
MXN6,936
Viewed 5 hours ago
Round trip
Economy
Guadalajara (GDL)to
Santo Domingo (SDQ)May 28, 2026 - Jun 11, 2026
From
MXN7,042
Viewed 1 day ago
Round trip
Economy
*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.
Plan your next trip to Santo Domingo with these low fares
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MXN
Mexico City (MEX)to
Santo Domingo (SDQ)
Apr 23, 2026 - Apr 30, 2026
Round trip
Economy
From
MXN5,479
Viewed 4 hours ago
Felipe Angeles, Mexico City (NLU)to
Santo Domingo (SDQ)
May 19, 2026 - May 23, 2026
Round trip
Economy
From
MXN5,502
Viewed 1 day ago
Cancun (CUN)to
Santo Domingo (SDQ)
Jun 25, 2026 - Jul 01, 2026
Round trip
Economy
From
MXN6,220
Viewed 8 hours ago
Monterrey (MTY)to
Santo Domingo (SDQ)
Jun 14, 2026 - Jun 21, 2026
Round trip
Economy
From
MXN7,011
Viewed 1 day ago
Guadalajara (GDL)to
Santo Domingo (SDQ)
May 28, 2026 - Jun 11, 2026
Round trip
Economy
From
MXN7,042
Viewed 1 day ago
*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.
Fly to Santo Domingo with Copa Air
The oldest city of the New World is Santo Domingo. Here you can find historic evidence that drastically contrasts with the modern dance clubs and cafes fond in the pier. Fly to Santo Domingo and discover this city with Copa Airlines.
What can you do in Santo Domingo?
- Night life: you can dance a nice merengue at discos and clubs. Also, you can spend a funny and entertaining night at one of the casinos in the city.
- Shopping: Dominican amber and other local products can be found in the Modelo Market, which is the national one. Additionally, you can find malls in the center of the city, which is a much modern option.
- Historic attractions: being such an old city, there are constructions like Columbus Alcazar and the Cathedral called Primate of the Americas, which represent a must-see in your trip to Santo Domingo.
Transportation in Santo Domingo
There’s a convenient subway system that is really fast and efficient, as well as cheap. You can also get a taxi, just keep in mind that collective transportation is very popular around the city. Remember that when you fly to Santo Domingo with Copa Airlines, you can make reservations for renting a car that gets you around Santo Domingo on our website at copa.com
