Find Copa Airlines flights to Santo Domingo (SDQ) from MXN5,893*

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Fares for flights to Santo Domingo through the Hub of the Americas®,in Panama City

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Mexico City (MEX)to

Santo Domingo (SDQ)
Apr 13, 2026 - Apr 25, 2026
From
MXN5,893
Viewed 7 minutes ago
Round trip
Economy

Cancun (CUN)to

Santo Domingo (SDQ)
May 20, 2026 - May 26, 2026
From
MXN6,302
Viewed 1 hour ago
Round trip
Economy

Monterrey (MTY)to

Santo Domingo (SDQ)
Apr 13, 2026 - May 13, 2026
From
MXN8,336
Viewed 1 day ago
Round trip
Economy

Guadalajara (GDL)to

Santo Domingo (SDQ)
Apr 25, 2026 - Apr 30, 2026
From
MXN9,447
Viewed 2 hours ago
Round trip
Economy

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Plan your next trip to Santo Domingo with these low fares

MXN

Mexico City (MEX)to

Santo Domingo (SDQ)
May 18, 2026 - May 24, 2026

Round trip

Economy

From
MXN5,947
Viewed 50 minutes ago

Cancun (CUN)to

Santo Domingo (SDQ)
May 20, 2026 - May 26, 2026

Round trip

Economy

From
MXN6,302
Viewed 1 hour ago

Felipe Angeles, Mexico City (NLU)to

Santo Domingo (SDQ)
Jun 26, 2026 - Jun 28, 2026

Round trip

Economy

From
MXN7,030
Viewed 8 hours ago

Monterrey (MTY)to

Santo Domingo (SDQ)
Jun 10, 2026 - Jun 17, 2026

Round trip

Economy

From
MXN9,234
Viewed 6 hours ago

Guadalajara (GDL)to

Santo Domingo (SDQ)
May 13, 2026 - May 17, 2026

Round trip

Economy

From
MXN9,471
Viewed 1 day ago

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Fly to Santo Domingo with Copa Air

The oldest city of the New World is Santo Domingo. Here you can find historic evidence that drastically contrasts with the modern dance clubs and cafes fond in the pier. Fly to Santo Domingo and discover this city with Copa Airlines.

What can you do in Santo Domingo?

  • Night life: you can dance a nice merengue at discos and clubs. Also, you can spend a funny and entertaining night at one of the casinos in the city.
  • Shopping: Dominican amber and other local products can be found in the Modelo Market, which is the national one. Additionally, you can find malls in the center of the city, which is a much modern option.
  • Historic attractions: being such an old city, there are constructions like Columbus Alcazar and the Cathedral called Primate of the Americas, which represent a must-see in your trip to Santo Domingo.

Transportation in Santo Domingo

There’s a convenient subway system that is really fast and efficient, as well as cheap. You can also get a taxi, just keep in mind that collective transportation is very popular around the city. Remember that when you fly to Santo Domingo with Copa Airlines, you can make reservations for renting a car that gets you around Santo Domingo on our website at copa.com