Find Copa Airlines flights from Panama from USD85*

1 Passenger

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Departure

Return

Restrictions apply; please see Terms & Conditions.

Offers on flights from Panama

From

Budget

USD

Panama (PTY)to

Miami (MIA)

Sep 02, 2026 - Sep 08, 2026

From

USD371

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

Medellin (MDE)

Apr 27, 2026 - Apr 29, 2026

From

USD237

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

David (DAV)

Mar 28, 2026 - Apr 04, 2026

From

USD85

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

Bogota (BOG)

May 08, 2026 - May 14, 2026

From

USD212

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

Orlando (MCO)

Sep 17, 2026 - Sep 23, 2026

From

USD441

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

San José (SJO)

Feb 07, 2026 - Feb 16, 2026

From

USD225

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

Caracas (CCS)

Mar 17, 2026 - Mar 26, 2026

From

USD559

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

Mexico City (MEX)

Apr 12, 2026 - Apr 27, 2026

From

USD352

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

New York (JFK)

Oct 11, 2026 - Oct 19, 2026

From

USD514

Viewed 1 day ago

Round trip

Economy

David (DAV)to

Panama (PTY)

Mar 06, 2026 - Mar 09, 2026

From

USD85

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

Cancun (CUN)

May 01, 2026 - May 08, 2026

From

USD331

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

Cartagena (CTG)

Mar 23, 2026 - Mar 26, 2026

From

USD317

Viewed 1 day ago

Round trip

Economy

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Lowest fares from Panama

From

Budget

USD

Panama (PTY)to

Miami (MIA)

Mar 26, 2026 - Mar 28, 2026

Round trip

Economy

From

USD371

Viewed 1 day ago

Panama (PTY)to

Medellin (MDE)

Mar 13, 2026 - Apr 13, 2026

Round trip

Economy

From

USD237

Viewed 1 day ago

Panama (PTY)to

Bogota (BOG)

May 08, 2026 - May 14, 2026

Round trip

Economy

From

USD212

Viewed 1 day ago

Panama (PTY)to

David (DAV)

Mar 07, 2026 - Mar 10, 2026

Round trip

Economy

From

USD85

Viewed 1 day ago

Panama (PTY)to

Orlando (MCO)

May 09, 2026 - May 16, 2026

Round trip

Economy

From

USD441

Viewed 1 day ago

Panama (PTY)to

Mexico City (MEX)

Apr 14, 2026 - Apr 29, 2026

Round trip

Economy

From

USD352

Viewed 1 day ago

Travel from Panama

Traveling from Panama

From the Hub of the Americas in Panama, you can go anywhere on the continent when you travel with Copa Airlines. Whether you’re traveling out of Panama City (PTY) or David (DAV), Copa Airlines connects you to more than 78 destinations in more than 30 countries across North, Central, and South America and the Caribbean.

You can purchase your ticket and manage your reservation from the comfort of your own home at copa.com. You can also book a hotel room, rent a car, and purchase travel insurance, all on the same site. Savor the experience of traveling on a world-class airline. You’ll enjoy safe, on-time travel and full, friendly service, including in-flight entertainment and complimentary beverages.