Find Copa Airlines flights to Medellin (MDE) from USD253*

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Restrictions apply; please see Terms & Conditions.

Fares for flights to Medellin through the Hub of the Americas®,in Panama City

USD

Los Angeles (LAX)to

Medellin (MDE)
Nov 12, 2025 - Nov 19, 2025
From
USD381
Viewed 1 day ago
Round trip
Economy

Boston (BOS)to

Medellin (MDE)
Nov 07, 2025 - Nov 16, 2025
From
USD363
Viewed 1 day ago
Round trip
Economy

Orlando (MCO)to

Medellin (MDE)
Sep 22, 2025 - Sep 26, 2025
From
USD291
Viewed 1 day ago
Round trip
Economy

New York (JFK)to

Medellin (MDE)
Nov 08, 2025 - Nov 15, 2025
From
USD357
Viewed 1 day ago
Round trip
Economy

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Plan your next trip to Medellin with these low fares

USD

Los Angeles (LAX)to

Medellin (MDE)
Oct 26, 2025 - Nov 27, 2025

Round trip

Economy

From
USD381
Viewed 1 day ago

Boston (BOS)to

Medellin (MDE)
Nov 07, 2025 - Nov 16, 2025

Round trip

Economy

From
USD363
Viewed 1 day ago

Orlando (MCO)to

Medellin (MDE)
Oct 22, 2025 - Oct 26, 2025

Round trip

Economy

From
USD291
Viewed 1 day ago

New York (JFK)to

Medellin (MDE)
Dec 02, 2025 - Dec 06, 2025

Round trip

Economy

From
USD357
Viewed 1 day ago

Tampa (TPA)to

Medellin (MDE)
Nov 07, 2025 - Nov 12, 2025

Round trip

Economy

From
USD311
Viewed 5 hours ago

Washington Dulles (IAD)to

Medellin (MDE)
Nov 03, 2025 - Nov 12, 2025

Round trip

Economy

From
USD265
Viewed 4 hours ago

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Fly to Medellin with Copa Air

Travel to Medellin with Copa Airlines and discover one of the largest cities in South America, combining the old and the new in its architecture and museums. In addition, it was the birthplace of the artist Fernando Botero.

Explore Medellin

  • Museums: The Antioquia Museum is one of the best known in Colombia and houses a large collection of works of art donated by the painter Botero.
  • Architectural contrasts: On the one hand, there is the romantic style of the Metropolitan Cathedral and on the other, modern buildings such as the Biblioteca España.
  • Contact with nature: You can visit places full of natural life like Explora Park, Barefoot Park and Botanical Garden.
  • Active nights: The nightlife of Medellin is lively and in Lleras Park are many bars and nightclubs where you can spend a fun night. For something more chic, Via de Las Palmas is a wonderful street to explore.

Transportation in Medellín

This modern city has efficient public transport systems. Take the Metro to avoid mishaps with transit or go through some of the Metrocable lines, a public transport by cable car that is seen in few parts of the world. The journey from the airport to the city is long, so book a car from when you purchase your flight to Medellin in copa.com or use the public service buses that connect to the San Diego Mall.