Find Copa Airlines flights to Santa Cruz (VVI) from USD 570*

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Restrictions apply; please see Terms & Conditions.

Fares for flights to Santa Cruz through the Hub of the Americas®,in Panama City

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Miami (MIA)to

Santa Cruz (VVI)
Jun 01, 2026 - Jun 15, 2026
From
USD 578
Viewed 1 day ago
Round trip
Economy

Washington Dulles (IAD)to

Santa Cruz (VVI)
May 31, 2026 - Jun 12, 2026
From
USD 588
Viewed 1 day ago
Round trip
Economy

New York (JFK)to

Santa Cruz (VVI)
Sep 21, 2026 - Sep 29, 2026
From
USD 638
Viewed 1 day ago
Round trip
Economy

Los Angeles (LAX)to

Santa Cruz (VVI)
May 24, 2026 - Jun 01, 2026
From
USD 738
Viewed 17 hours ago
Round trip
Economy

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Plan your next trip to Santa Cruz with these low fares

USD

Miami (MIA)to

Santa Cruz (VVI)
May 27, 2026 - May 30, 2026

Round trip

Economy

From
USD 578
Viewed 1 day ago

Washington Dulles (IAD)to

Santa Cruz (VVI)
May 31, 2026 - Jun 12, 2026

Round trip

Economy

From
USD 588
Viewed 1 day ago

New York (JFK)to

Santa Cruz (VVI)
Sep 21, 2026 - Sep 29, 2026

Round trip

Economy

From
USD 638
Viewed 1 day ago

Los Angeles (LAX)to

Santa Cruz (VVI)
May 27, 2026 - Aug 22, 2026

Round trip

Economy

From
USD 738
Viewed 1 day ago

San Francisco (SFO)to

Santa Cruz (VVI)
Aug 12, 2026 - Aug 30, 2026

Round trip

Economy

From
USD 834
Viewed 31 minutes ago

Boston (BOS)to

Santa Cruz (VVI)
Oct 19, 2026 - Oct 26, 2026

Round trip

Economy

From
USD 858
Viewed 1 day ago

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Fly to Santa Cruz with Copa Air

Santa Cruz receives a third of Bolivia's tourists, attracted by its cultural capital and its entertainment and relaxation activities. Copa Airlines offers flights to Santa Cruz from different parts of the Americas.

What to visit in Santa Cruz?

  • Colonial footprints: the Plaza 24 de Septiembre, located in the city center, is surrounded by buildings dating back to the colonial era, such as the Metropolitan Cathedral, City Hall, and the Cultural Center.
  • Outings in the fresh air: surrounding the city are numerous nature reserves where you can discover the local flora and fauna, participate in outdoor actives, and relax. The most popular are Las Lomas de Arena Regional Park, the Güembé Biocenter, and the Ivaga Guazú Ecological Park.
  • Go shopping: Santa Cruz boasts malls and shops with domestic and imported items, where you can buy a variety of products and gifts.

Getting around Santa Cruz

The simplest way of touring the city is to use some of the 132 urban bus routes. You can also rent a car or take a taxi to reach more remote destinations. Thanks to the excellent service aboard Copa Airlines, your flight to Santa Cruz will be a very pleasant experience. Book your flight today.