Find Copa Airlines flights to Sao Paulo (GRU) from USD540*

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Restrictions apply; please see Terms & Conditions.

Fares for flights to Sao Paulo through the Hub of the Americas®,in Panama City

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Orlando (MCO)to

Sao Paulo (GRU)
Mar 17, 2026 - Mar 22, 2026
From
USD570
Viewed 1 hour ago
Round trip
Economy

Boston (BOS)to

Sao Paulo (GRU)
Apr 12, 2026 - Apr 21, 2026
From
USD580
Viewed 1 day ago
Round trip
Economy

San Francisco (SFO)to

Sao Paulo (GRU)
May 04, 2026 - May 14, 2026
From
USD740
Viewed 1 day ago
Round trip
Economy

Chicago (ORD)to

Sao Paulo (GRU)
May 12, 2026 - May 27, 2026
From
USD748
Viewed 1 day ago
Round trip
Economy

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Plan your next trip to Sao Paulo with these low fares

USD

Washington Dulles (IAD)to

Sao Paulo (GRU)
May 03, 2026 - May 15, 2026

Round trip

Economy

From
USD540
Viewed 1 day ago

Boston (BOS)to

Sao Paulo (GRU)
May 15, 2026 - May 18, 2026

Round trip

Economy

From
USD580
Viewed 17 hours ago

Los Angeles (LAX)to

Sao Paulo (GRU)
Apr 29, 2026 - May 06, 2026

Round trip

Economy

From
USD610
Viewed 1 day ago

Orlando (MCO)to

Sao Paulo (GRU)
Sep 03, 2026 - Sep 22, 2026

Round trip

Economy

From
USD619
Viewed 1 day ago

San Francisco (SFO)to

Sao Paulo (GRU)
May 04, 2026 - May 14, 2026

Round trip

Economy

From
USD740
Viewed 1 day ago

Chicago (ORD)to

Sao Paulo (GRU)
May 12, 2026 - May 27, 2026

Round trip

Economy

From
USD748
Viewed 1 day ago

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Fly to Sao Paulo with Copa Air

Whether you're traveling for business or for pleasure, book a flight to Sao Paulo with Copa Airlines and travel comfortably with varied entertainment and delicious food on board.

Main attractions in Sao Paulo:

  • Museums for everyone: this big metropolis has a large variety of museums such as the Acervo do Palácia dos Bandeirantes (Brazilian art), Casa das Rosas (library), and the Latin American Memorial (history).
  • Fun and Party: without a doubt Vila Madalena has become a reference point in the city with hundreds of restaurants, bars, art galleries, and stores. It's where the best night life takes place.
  • Avenida Paulista: visit Sao Paulo's main avenue, the home of many international restaurants, stores, and shopping malls. Lined with picturesque buildings, it's the perfect place to spend the day shopping!
  • Outdoor walks: the Ibirapuera Park is the ideal place for those who want to walk, ride a bike, or have an outdoor picnic. It has museums, plant nurseries, a Japanese garden, and fountains with light shows.

Getting around Sao Paulo

To get around the city, we recommend the metro, bus, and trains. The traffic makes driving a car take a lot longer than taking public transportation. Travel with Panama's leading airline and enjoy a one of a kind service on board. Book your flight to Sao Paulo with Copa Airlines today and earn miles with our loyalty plan, ConnectMiles.