Find Copa Airlines flights to Sao Paulo (GRU) from USD 455*

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Restrictions apply; please see Terms & Conditions.

Fares for flights to Sao Paulo through the Hub of the Americas®,in Panama City

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Medellin (MDE)to

Sao Paulo (GRU)
Oct 16, 2026 - Oct 25, 2026
From
USD 479
Viewed 1 day ago
Round trip
Economy

Panama (PTY)to

Sao Paulo (GRU)
Aug 07, 2026 - Aug 10, 2026
From
USD 489
Viewed 1 day ago
Round trip
Economy

Quito (UIO)to

Sao Paulo (GRU)
Feb 27, 2027 - Mar 31, 2027
From
USD 574
Viewed 1 day ago
Round trip
Economy

Orlando (MCO)to

Sao Paulo (GRU)
Nov 13, 2026 - Nov 19, 2026
From
USD 592
Viewed 1 day ago
Round trip
Economy

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Plan your next trip to Sao Paulo with these low fares

USD

San José (SJO)to

Sao Paulo (GRU)
Sep 09, 2026 - Oct 04, 2026

Round trip

Economy

From
USD 456
Viewed 1 day ago

Medellin (MDE)to

Sao Paulo (GRU)
Oct 16, 2026 - Oct 25, 2026

Round trip

Economy

From
USD 479
Viewed 1 day ago

Panama (PTY)to

Sao Paulo (GRU)
Oct 05, 2026 - Oct 16, 2026

Round trip

Economy

From
USD 490
Viewed 1 day ago

Quito (UIO)to

Sao Paulo (GRU)
Sep 12, 2026 - Sep 26, 2026

Round trip

Economy

From
USD 574
Viewed 1 day ago

Orlando (MCO)to

Sao Paulo (GRU)
Nov 13, 2026 - Nov 19, 2026

Round trip

Economy

From
USD 592
Viewed 1 day ago

Guayaquil (GYE)to

Sao Paulo (GRU)
Sep 08, 2026 - Sep 10, 2026

Round trip

Economy

From
USD 632
Viewed 1 day ago

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Fly to Sao Paulo with Copa Air

Whether you're traveling for business or for pleasure, book a flight to Sao Paulo with Copa Airlines and travel comfortably with varied entertainment and delicious food on board.

Main attractions in Sao Paulo:

  • Museums for everyone: this big metropolis has a large variety of museums such as the Acervo do Palácia dos Bandeirantes (Brazilian art), Casa das Rosas (library), and the Latin American Memorial (history).
  • Fun and Party: without a doubt Vila Madalena has become a reference point in the city with hundreds of restaurants, bars, art galleries, and stores. It's where the best night life takes place.
  • Avenida Paulista: visit Sao Paulo's main avenue, the home of many international restaurants, stores, and shopping malls. Lined with picturesque buildings, it's the perfect place to spend the day shopping!
  • Outdoor walks: the Ibirapuera Park is the ideal place for those who want to walk, ride a bike, or have an outdoor picnic. It has museums, plant nurseries, a Japanese garden, and fountains with light shows.

Getting around Sao Paulo

To get around the city, we recommend the metro, bus, and trains. The traffic makes driving a car take a lot longer than taking public transportation. Travel with Panama's leading airline and enjoy a one of a kind service on board. Book your flight to Sao Paulo with Copa Airlines today and earn miles with our loyalty plan, ConnectMiles.