Find Copa Airlines flights to Medellin (MDE) from USD263*

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Restrictions apply; please see Terms & Conditions.

Fares for flights to Medellin through the Hub of the Americas®,in Panama City

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New York (JFK)to

Medellin (MDE)
Apr 10, 2026 - Apr 23, 2026
From
USD375
Viewed 1 day ago
Round trip
Economy

Chicago (ORD)to

Medellin (MDE)
Apr 07, 2026 - May 06, 2026
From
USD392
Viewed 1 day ago
Round trip
Economy

Los Angeles (LAX)to

Medellin (MDE)
May 05, 2026 - May 19, 2026
From
USD397
Viewed 1 day ago
Round trip
Economy

Boston (BOS)to

Medellin (MDE)
Apr 20, 2026 - Jul 31, 2026
From
USD405
Viewed 1 day ago
Round trip
Economy

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Plan your next trip to Medellin with these low fares

USD

Tampa (TPA)to

Medellin (MDE)
May 20, 2026 - May 26, 2026

Round trip

Economy

From
USD306
Viewed 13 hours ago

Atlanta (ATL)to

Medellin (MDE)
May 17, 2026 - May 31, 2026

Round trip

Economy

From
USD334
Viewed 1 day ago

New York (JFK)to

Medellin (MDE)
Jul 27, 2026 - Aug 06, 2026

Round trip

Economy

From
USD375
Viewed 15 hours ago

Chicago (ORD)to

Medellin (MDE)
Jun 04, 2026 - Jun 09, 2026

Round trip

Economy

From
USD392
Viewed 1 day ago

Los Angeles (LAX)to

Medellin (MDE)
May 14, 2026 - May 18, 2026

Round trip

Economy

From
USD397
Viewed 1 day ago

Boston (BOS)to

Medellin (MDE)
May 07, 2026 - May 23, 2026

Round trip

Economy

From
USD405
Viewed 1 day ago

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Fly to Medellin with Copa Air

Travel to Medellin with Copa Airlines and discover one of the largest cities in South America, combining the old and the new in its architecture and museums. In addition, it was the birthplace of the artist Fernando Botero.

Explore Medellin

  • Museums: The Antioquia Museum is one of the best known in Colombia and houses a large collection of works of art donated by the painter Botero.
  • Architectural contrasts: On the one hand, there is the romantic style of the Metropolitan Cathedral and on the other, modern buildings such as the Biblioteca España.
  • Contact with nature: You can visit places full of natural life like Explora Park, Barefoot Park and Botanical Garden.
  • Active nights: The nightlife of Medellin is lively and in Lleras Park are many bars and nightclubs where you can spend a fun night. For something more chic, Via de Las Palmas is a wonderful street to explore.

Transportation in Medellín

This modern city has efficient public transport systems. Take the Metro to avoid mishaps with transit or go through some of the Metrocable lines, a public transport by cable car that is seen in few parts of the world. The journey from the airport to the city is long, so book a car from when you purchase your flight to Medellin in copa.com or use the public service buses that connect to the San Diego Mall.