Find Copa Airlines flights from Medellin (MDE) to Guayaquil (GYE) from COP1.083.476*
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Restrictions apply; please see Terms & Conditions.
Best prices on Medellin to Guayaquil flights
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Best airfares from Medellin to Guayaquil flights
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From | To | Fare Type | Dates | Price |
|---|---|---|---|---|
| Medellin (MDE) | Guayaquil (GYE) | Round trip / Economy | Oct 07, 2025 - Oct 14, 2025 | From COP1.083.476 Viewed 1 day ago |
| Medellin (MDE) | Guayaquil (GYE) | Round trip / Economy | Sep 02, 2025 - Sep 09, 2025 | From COP1.116.278 Viewed 1 hour ago |
| Medellin (MDE) | Guayaquil (GYE) | Round trip / Economy | Sep 04, 2025 - Sep 08, 2025 | From COP1.114.207 Viewed 19 hours ago |
| Medellin (MDE) | Guayaquil (GYE) | Round trip / Economy | Sep 12, 2025 - Sep 20, 2025 | From COP1.146.338 Viewed 17 hours ago |
| Medellin (MDE) | Guayaquil (GYE) | Round trip / Economy | Nov 14, 2025 - Feb 14, 2026 | From COP1.270.607 Viewed 1 day ago |
*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.
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