What is the best fare to fly from Medellin?

The best fare to fly from Medellin starts at **Flights.FromLowestPrice**. Fly with Copa Airlines.

Find Copa Airlines flights from Medellin (MDE) from COP 927.130*

1 Passenger

Promo Code

From

Departure

Return

Restrictions apply; please see Terms & Conditions.

Offers on flights from Medellin

From

Budget

COP

Medellin (MDE)to

Panama (PTY)

Oct 23, 2026 - Oct 27, 2026

From

COP 927.130

Viewed 1 day ago

Round trip

Economy

Medellin (MDE)to

Punta Cana (PUJ)

Aug 12, 2026 - Aug 15, 2026

From

COP 1.257.228

Viewed 8 hours ago

Round trip

Economy

Medellin (MDE)to

Mexico City (MEX)

Aug 27, 2026 - Sep 02, 2026

From

COP 1.271.450

Viewed 1 day ago

Round trip

Economy

Medellin (MDE)to

Boston (BOS)

Oct 10, 2026 - Oct 27, 2026

From

COP 1.296.590

Viewed 2 hours ago

Round trip

Economy

Medellin (MDE)to

Cancun (CUN)

Sep 05, 2026 - Sep 12, 2026

From

COP 1.309.232

Viewed 1 day ago

Round trip

Economy

Medellin (MDE)to

New York (JFK)

May 06, 2027 - May 12, 2027

From

COP 1.342.150

Viewed 1 day ago

Round trip

Economy

Medellin (MDE)to

Miami (MIA)

Dec 17, 2026 - Jan 04, 2027

From

COP 1.343.892

Viewed 1 day ago

Round trip

Economy

Medellin (MDE)to

Orlando (MCO)

Nov 04, 2026 - Nov 16, 2026

From

COP 1.366.720

Viewed 1 day ago

Round trip

Economy

Medellin (MDE)to

Santiago de Chile (SCL)

Aug 13, 2026 - Aug 18, 2026

From

COP 1.479.438

Viewed 1 day ago

Round trip

Economy

Medellin (MDE)to

Sao Paulo (GRU)

Aug 24, 2026 - Aug 31, 2026

From

COP 1.533.712

Viewed 1 day ago

Round trip

Economy

Medellin (MDE)to

Los Angeles (LAX)

Nov 14, 2026 - Nov 23, 2026

From

COP 1.628.227

Viewed 1 day ago

Round trip

Economy

Medellin (MDE)to

Rio de Janeiro (GIG)

Sep 10, 2026 - Sep 17, 2026

From

COP 1.663.894

Viewed 1 day ago

Round trip

Economy

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Best prices on Medellin flights

From

Budget

COP

Medellin (MDE)to

Panama (PTY)

Oct 23, 2026 - Oct 27, 2026

Round trip

Economy

From

COP 927.130

Viewed 1 day ago

Medellin (MDE)to

Boston (BOS)

Oct 10, 2026 - Oct 27, 2026

Round trip

Economy

From

COP 1.296.590

Viewed 2 hours ago

Medellin (MDE)to

Miami (MIA)

Dec 17, 2026 - Jan 04, 2027

Round trip

Economy

From

COP 1.343.892

Viewed 1 day ago

Medellin (MDE)to

Orlando (MCO)

Nov 06, 2026 - Nov 16, 2026

Round trip

Economy

From

COP 1.366.720

Viewed 1 day ago

Medellin (MDE)to

Sao Paulo (GRU)

Nov 21, 2026 - Nov 30, 2026

Round trip

Economy

From

COP 1.533.968

Viewed 1 day ago

Medellin (MDE)to

Rio de Janeiro (GIG)

Sep 10, 2026 - Sep 17, 2026

Round trip

Economy

From

COP 1.663.894

Viewed 1 day ago

Flights from Medellin with Copa Airlines

Depart on a flight from Medellin with Copa Airlines and take advantage of the extensive network of destinations we offer, as well as complimentary drinks and the loyalty program of ConnectMiles, ideal for frequent travelers.

The José María Córdova International Airport

Depart from Medellin at the José María Córdova International Airport (MDE), which is almost an hour away from the city, so take your precautions when you take your flight. This airport operates 24 hours a day and has three restaurants and a commercial area with banking and bureau de change services. Arrive at the airport by taxi, one of the public service buses leaving the San Diego Mall or a rental car.