What is the best fare to fly from Medellin?

The best fare to fly from Medellin starts at **Flights.FromLowestPrice**. Fly with Copa Airlines.

Find Copa Airlines flights from Medellin (MDE) from COP 894.010*

1 Passenger

Promo Code

From

Departure

Return

Restrictions apply; please see Terms & Conditions.

Offers on flights from Medellin

From

Budget

COP

Medellin (MDE)to

Panama (PTY)

Oct 26, 2026 - Oct 26, 2026

From

COP 894.010

Viewed 3 hours ago

Round trip

Economy

Medellin (MDE)to

San José (SJO)

Oct 07, 2026 - Nov 17, 2026

From

COP 944.410

Viewed 10 hours ago

Round trip

Economy

Medellin (MDE)to

Miami (MIA)

Sep 27, 2026 - Oct 30, 2026

From

COP 1.248.000

Viewed 3 hours ago

Round trip

Economy

Medellin (MDE)to

Punta Cana (PUJ)

Nov 11, 2026 - Nov 14, 2026

From

COP 1.274.376

Viewed 4 hours ago

Round trip

Economy

Medellin (MDE)to

Cancun (CUN)

Nov 11, 2026 - Nov 17, 2026

From

COP 1.290.696

Viewed 3 hours ago

Round trip

Economy

Medellin (MDE)to

Boston (BOS)

Oct 20, 2026 - Nov 04, 2026

From

COP 1.301.816

Viewed 2 hours ago

Round trip

Economy

Medellin (MDE)to

Orlando (MCO)

Mar 01, 2027 - Mar 08, 2027

From

COP 1.409.470

Viewed 3 hours ago

Round trip

Economy

Medellin (MDE)to

New York (JFK)

Dec 10, 2026 - Feb 28, 2027

From

COP 1.462.092

Viewed 1 day ago

Round trip

Economy

Medellin (MDE)to

Mexico City (MEX)

Oct 20, 2026 - Oct 24, 2026

From

COP 1.550.578

Viewed 5 hours ago

Round trip

Economy

Medellin (MDE)to

Rio de Janeiro (GIG)

Sep 22, 2026 - Sep 27, 2026

From

COP 1.667.674

Viewed 6 hours ago

Round trip

Economy

Medellin (MDE)to

Sao Paulo (GRU)

Oct 29, 2026 - Nov 10, 2026

From

COP 1.670.674

Viewed 4 hours ago

Round trip

Economy

Medellin (MDE)to

Los Angeles (LAX)

Nov 09, 2026 - Nov 13, 2026

From

COP 1.678.610

Viewed 4 hours ago

Round trip

Economy

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Best prices on Medellin flights

From

Budget

COP

Medellin (MDE)to

Panama (PTY)

Oct 22, 2026 - Oct 26, 2026

Round trip

Economy

From

COP 894.010

Viewed 3 hours ago

Medellin (MDE)to

Miami (MIA)

Oct 21, 2026 - Oct 30, 2026

Round trip

Economy

From

COP 1.248.000

Viewed 4 hours ago

Medellin (MDE)to

Cancun (CUN)

Nov 12, 2026 - Nov 17, 2026

Round trip

Economy

From

COP 1.290.696

Viewed 3 hours ago

Medellin (MDE)to

Boston (BOS)

Oct 20, 2026 - Nov 04, 2026

Round trip

Economy

From

COP 1.301.816

Viewed 2 hours ago

Medellin (MDE)to

Orlando (MCO)

Mar 01, 2027 - Mar 08, 2027

Round trip

Economy

From

COP 1.409.470

Viewed 3 hours ago

Medellin (MDE)to

New York (JFK)

Dec 10, 2026 - Feb 28, 2027

Round trip

Economy

From

COP 1.462.092

Viewed 1 day ago

Flights from Medellin with Copa Airlines

Depart on a flight from Medellin with Copa Airlines and take advantage of the extensive network of destinations we offer, as well as complimentary drinks and the loyalty program of ConnectMiles, ideal for frequent travelers.

The José María Córdova International Airport

Depart from Medellin at the José María Córdova International Airport (MDE), which is almost an hour away from the city, so take your precautions when you take your flight. This airport operates 24 hours a day and has three restaurants and a commercial area with banking and bureau de change services. Arrive at the airport by taxi, one of the public service buses leaving the San Diego Mall or a rental car.