What is the best fare to fly from Medellin?

The best fare to fly from Medellin starts at **Flights.FromLowestPrice**. Fly with Copa Airlines.

Find Copa Airlines flights from Medellin (MDE) from COP 1.043.338*

1 Passenger

Promo Code

From

Departure

Return

Restrictions apply; please see Terms & Conditions.

Offers on flights from Medellin

From

Budget

COP

Medellin (MDE)to

Panama (PTY)

Jun 09, 2026 - Jun 17, 2026

From

COP 1.043.338

Viewed 1 day ago

Round trip

Economy

Medellin (MDE)to

Orlando (MCO)

May 27, 2026 - Jun 03, 2026

From

COP 1.161.240

Viewed 1 day ago

Round trip

Economy

Medellin (MDE)to

Atlanta (ATL)

Jun 11, 2026 - Jun 21, 2026

From

COP 1.177.086

Viewed 1 day ago

Round trip

Economy

Medellin (MDE)to

Miami (MIA)

May 06, 2026 - May 13, 2026

From

COP 1.200.898

Viewed 10 hours ago

Round trip

Economy

Medellin (MDE)to

New York (JFK)

Sep 24, 2026 - Sep 30, 2026

From

COP 1.272.272

Viewed 9 hours ago

Round trip

Economy

Medellin (MDE)to

Cancun (CUN)

May 12, 2026 - Aug 14, 2026

From

COP 1.456.606

Viewed 1 day ago

Round trip

Economy

Medellin (MDE)to

Punta Cana (PUJ)

Jun 08, 2026 - Jun 12, 2026

From

COP 1.461.742

Viewed 8 hours ago

Round trip

Economy

Medellin (MDE)to

Sao Paulo (GRU)

May 12, 2026 - May 26, 2026

From

COP 1.625.404

Viewed 1 day ago

Round trip

Economy

Medellin (MDE)to

Boston (BOS)

May 27, 2026 - May 31, 2026

From

COP 1.684.724

Viewed 1 day ago

Round trip

Economy

Medellin (MDE)to

Mexico City (MEX)

Jun 02, 2026 - Jun 08, 2026

From

COP 1.734.266

Viewed 13 hours ago

Round trip

Economy

Medellin (MDE)to

Rio de Janeiro (GIG)

Jun 19, 2026 - Jun 25, 2026

From

COP 1.860.354

Viewed 1 day ago

Round trip

Economy

Medellin (MDE)to

Los Angeles (LAX)

May 14, 2026 - May 18, 2026

From

COP 1.994.070

Viewed 12 hours ago

Round trip

Economy

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Best prices on Medellin flights

From

Budget

COP

Medellin (MDE)to

Panama (PTY)

Jun 09, 2026 - Jun 17, 2026

Round trip

Economy

From

COP 1.043.338

Viewed 1 day ago

Medellin (MDE)to

Orlando (MCO)

Jun 06, 2026 - Jun 26, 2026

Round trip

Economy

From

COP 1.161.240

Viewed 1 day ago

Medellin (MDE)to

Miami (MIA)

Jun 11, 2026 - Jun 24, 2026

Round trip

Economy

From

COP 1.319.874

Viewed 1 day ago

Medellin (MDE)to

Boston (BOS)

Jul 11, 2026 - Jul 27, 2026

Round trip

Economy

From

COP 1.684.724

Viewed 1 day ago

Medellin (MDE)to

Mexico City (MEX)

Jun 02, 2026 - Jun 08, 2026

Round trip

Economy

From

COP 1.734.266

Viewed 13 hours ago

Medellin (MDE)to

Sao Paulo (GRU)

Aug 16, 2026 - Aug 25, 2026

Round trip

Economy

From

COP 2.021.990

Viewed 12 hours ago

Flights from Medellin with Copa Airlines

Depart on a flight from Medellin with Copa Airlines and take advantage of the extensive network of destinations we offer, as well as complimentary drinks and the loyalty program of ConnectMiles, ideal for frequent travelers.

The José María Córdova International Airport

Depart from Medellin at the José María Córdova International Airport (MDE), which is almost an hour away from the city, so take your precautions when you take your flight. This airport operates 24 hours a day and has three restaurants and a commercial area with banking and bureau de change services. Arrive at the airport by taxi, one of the public service buses leaving the San Diego Mall or a rental car.