What is the best fare to fly from Medellin?

The best fare to fly from Medellin starts at **Flights.FromLowestPrice**. Fly with Copa Airlines.

Find Copa Airlines flights from Medellin (MDE) from COP901.314*

1 Passenger

Promo Code

From

Departure

Return

Restrictions apply; please see Terms & Conditions.

Offers on flights from Medellin

From

Budget

COP

Medellin (MDE)to

Panama (PTY)

Feb 10, 2026 - Feb 20, 2026

From

COP901.314

Viewed 7 hours ago

Round trip
/
Economy

Medellin (MDE)to

Mexico City (MEX)

Nov 19, 2025 - Nov 28, 2025

From

COP1.275.486

Viewed 1 day ago

Round trip
/
Economy

Medellin (MDE)to

Orlando (MCO)

Nov 13, 2025 - Nov 20, 2025

From

COP1.125.370

Viewed 1 day ago

Round trip
/
Economy

Medellin (MDE)to

Guatemala (GUA)

Nov 24, 2025 - Nov 27, 2025

From

COP1.040.756

Viewed 1 day ago

Round trip
/
Economy

Medellin (MDE)to

Santiago de Chile (SCL)

Nov 13, 2025 - Feb 22, 2026

From

COP1.638.400

Viewed 1 day ago

Round trip
/
Economy

Medellin (MDE)to

Boston (BOS)

Dec 24, 2025 - Jan 05, 2026

From

COP1.333.040

Viewed 11 hours ago

Round trip
/
Economy

Medellin (MDE)to

Los Angeles (LAX)

Dec 10, 2025 - Dec 10, 2025

From

COP1.430.520

Viewed 1 day ago

Round trip
/
Economy

Medellin (MDE)to

Miami (MIA)

Nov 20, 2025 - Nov 25, 2025

From

COP1.167.754

Viewed 1 day ago

Round trip
/
Economy

Medellin (MDE)to

Punta Cana (PUJ)

Dec 11, 2025 - Dec 14, 2025

From

COP1.402.664

Viewed 1 day ago

Round trip
/
Economy

Medellin (MDE)to

Cancun (CUN)

Nov 17, 2025 - Nov 26, 2025

From

COP1.270.232

Viewed 1 day ago

Round trip
/
Economy

Medellin (MDE)to

Sao Paulo (GRU)

Nov 08, 2025 - Nov 18, 2025

From

COP1.618.902

Viewed 1 day ago

Round trip
/
Economy

Medellin (MDE)to

New York (JFK)

Mar 24, 2026 - Apr 13, 2026

From

COP1.633.940

Viewed 4 hours ago

Round trip
/
Economy

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Best prices on Medellin flights

From

Budget

COP

Medellin (MDE)to
Panama (PTY)
Feb 10, 2026 - Feb 20, 2026
Round trip
/
Economy

From
COP901.314*
Viewed 7 hours ago

Medellin (MDE)to
Mexico City (MEX)
Dec 14, 2025 - Jan 31, 2026
Round trip
/
Economy

From
COP1.275.486*
Viewed 1 day ago

Medellin (MDE)to
Orlando (MCO)
Mar 04, 2026 - Mar 16, 2026
Round trip
/
Economy

From
COP1.125.370*
Viewed 9 hours ago

Medellin (MDE)to
Guatemala (GUA)
Jan 21, 2026 - Jan 28, 2026
Round trip
/
Economy

From
COP1.040.756*
Viewed 1 day ago

Medellin (MDE)to
Santiago de Chile (SCL)
Apr 23, 2026 - May 02, 2026
Round trip
/
Economy

From
COP1.638.400*
Viewed 12 hours ago

Medellin (MDE)to
Boston (BOS)
Jan 30, 2026 - Feb 19, 2026
Round trip
/
Economy

From
COP1.333.040*
Viewed 12 hours ago

Flights from Medellin with Copa Airlines

Depart on a flight from Medellin with Copa Airlines and take advantage of the extensive network of destinations we offer, as well as complimentary drinks and the loyalty program of ConnectMiles, ideal for frequent travelers.

The José María Córdova International Airport

Depart from Medellin at the José María Córdova International Airport (MDE), which is almost an hour away from the city, so take your precautions when you take your flight. This airport operates 24 hours a day and has three restaurants and a commercial area with banking and bureau de change services. Arrive at the airport by taxi, one of the public service buses leaving the San Diego Mall or a rental car.