What is the best fare to fly from Medellin?

The best fare to fly from Medellin starts at **Flights.FromLowestPrice**. Fly with Copa Airlines.

Find Copa Airlines flights from Medellin (MDE) from COP967.746*

1 Passenger

Promo Code

From

Departure

Return

Restrictions apply; please see Terms & Conditions.

Offers on flights from Medellin

From

Budget

COP

Medellin (MDE)to

Panama (PTY)

Mar 23, 2026 - Apr 11, 2026

From

COP1.029.324

Viewed 16 hours ago

Round trip

Economy

Medellin (MDE)to

Miami (MIA)

Apr 05, 2026 - Apr 12, 2026

From

COP1.187.364

Viewed 20 hours ago

Round trip

Economy

Medellin (MDE)to

Orlando (MCO)

May 09, 2026 - May 16, 2026

From

COP1.231.746

Viewed 1 day ago

Round trip

Economy

Medellin (MDE)to

Mexico City (MEX)

Apr 02, 2026 - May 04, 2026

From

COP1.332.390

Viewed 9 hours ago

Round trip

Economy

Medellin (MDE)to

New York (JFK)

Oct 01, 2026 - Nov 01, 2026

From

COP1.383.100

Viewed 2 hours ago

Round trip

Economy

Medellin (MDE)to

Cancun (CUN)

May 27, 2026 - May 31, 2026

From

COP1.486.772

Viewed 18 hours ago

Round trip

Economy

Medellin (MDE)to

Boston (BOS)

Apr 20, 2026 - May 06, 2026

From

COP1.582.846

Viewed 19 hours ago

Round trip

Economy

Medellin (MDE)to

Sao Paulo (GRU)

Apr 10, 2026 - Apr 22, 2026

From

COP1.593.698

Viewed 18 hours ago

Round trip

Economy

Medellin (MDE)to

Santiago de Chile (SCL)

Apr 01, 2026 - Apr 17, 2026

From

COP1.627.882

Viewed 1 day ago

Round trip

Economy

Medellin (MDE)to

Rio de Janeiro (GIG)

Mar 18, 2026 - Mar 26, 2026

From

COP1.647.296

Viewed 18 hours ago

Round trip

Economy

Medellin (MDE)to

Los Angeles (LAX)

Apr 21, 2026 - Apr 28, 2026

From

COP1.784.642

Viewed 15 hours ago

Round trip

Economy

Medellin (MDE)to

Buenos Aires (EZE)

Jun 02, 2026 - Jun 09, 2026

From

COP2.063.558

Viewed 19 hours ago

Round trip

Economy

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Best prices on Medellin flights

From

Budget

COP

Medellin (MDE)to

Panama (PTY)

May 05, 2026 - May 10, 2026

Round trip

Economy

From

COP1.029.324

Viewed 19 hours ago

Medellin (MDE)to

Miami (MIA)

Apr 19, 2026 - Apr 24, 2026

Round trip

Economy

From

COP1.187.364

Viewed 1 day ago

Medellin (MDE)to

Orlando (MCO)

May 11, 2026 - May 16, 2026

Round trip

Economy

From

COP1.231.746

Viewed 1 day ago

Medellin (MDE)to

Boston (BOS)

Apr 20, 2026 - May 06, 2026

Round trip

Economy

From

COP1.582.846

Viewed 19 hours ago

Medellin (MDE)to

Sao Paulo (GRU)

Jun 02, 2026 - Jun 09, 2026

Round trip

Economy

From

COP1.593.698

Viewed 1 day ago

Medellin (MDE)to

Santiago de Chile (SCL)

May 03, 2026 - May 07, 2026

Round trip

Economy

From

COP1.627.882

Viewed 23 hours ago

Flights from Medellin with Copa Airlines

Depart on a flight from Medellin with Copa Airlines and take advantage of the extensive network of destinations we offer, as well as complimentary drinks and the loyalty program of ConnectMiles, ideal for frequent travelers.

The José María Córdova International Airport

Depart from Medellin at the José María Córdova International Airport (MDE), which is almost an hour away from the city, so take your precautions when you take your flight. This airport operates 24 hours a day and has three restaurants and a commercial area with banking and bureau de change services. Arrive at the airport by taxi, one of the public service buses leaving the San Diego Mall or a rental car.