What is the best fare to fly from Medellin?

The best fare to fly from Medellin starts at **Flights.FromLowestPrice**. Fly with Copa Airlines.

Find Copa Airlines flights from Medellin (MDE) from COP 967.022*

1 Passenger

Promo Code

From

Departure

Return

Restrictions apply; please see Terms & Conditions.

Offers on flights from Medellin

From

Budget

COP

Medellin (MDE)to

Panama (PTY)

Sep 30, 2026 - Oct 02, 2026

From

COP 967.022

Viewed 8 hours ago

Round trip

Economy

Medellin (MDE)to

San José (SJO)

Jul 27, 2026 - Jul 30, 2026

From

COP 1.024.022

Viewed 7 hours ago

Round trip

Economy

Medellin (MDE)to

Miami (MIA)

Sep 11, 2026 - Sep 20, 2026

From

COP 1.234.112

Viewed 8 hours ago

Round trip

Economy

Medellin (MDE)to

Santiago de Chile (SCL)

Aug 13, 2026 - Aug 16, 2026

From

COP 1.287.854

Viewed 3 hours ago

Round trip

Economy

Medellin (MDE)to

New York (JFK)

Oct 19, 2026 - Oct 27, 2026

From

COP 1.315.204

Viewed 1 day ago

Round trip

Economy

Medellin (MDE)to

Mexico City (MEX)

Jun 18, 2026 - Jul 04, 2026

From

COP 1.367.778

Viewed 5 hours ago

Round trip

Economy

Medellin (MDE)to

Punta Cana (PUJ)

Jul 06, 2026 - Jul 10, 2026

From

COP 1.396.675

Viewed 7 hours ago

Round trip

Economy

Medellin (MDE)to

Cancun (CUN)

Aug 12, 2026 - Aug 16, 2026

From

COP 1.408.746

Viewed 5 hours ago

Round trip

Economy

Medellin (MDE)to

Orlando (MCO)

Oct 27, 2026 - Nov 02, 2026

From

COP 1.432.008

Viewed 8 hours ago

Round trip

Economy

Medellin (MDE)to

Tampa (TPA)

Jun 15, 2026 - Jul 28, 2026

From

COP 1.561.432

Viewed 1 day ago

Round trip

Economy

Medellin (MDE)to

Boston (BOS)

Oct 09, 2026 - Oct 13, 2026

From

COP 1.622.314

Viewed 5 hours ago

Round trip

Economy

Medellin (MDE)to

Los Angeles (LAX)

Jun 25, 2026 - Jun 29, 2026

From

COP 1.983.868

Viewed 6 hours ago

Round trip

Economy

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Best prices on Medellin flights

From

Budget

COP

Medellin (MDE)to

Panama (PTY)

Aug 12, 2026 - Aug 13, 2026

Round trip

Economy

From

COP 967.022

Viewed 8 hours ago

Medellin (MDE)to

Miami (MIA)

Sep 04, 2026 - Sep 13, 2026

Round trip

Economy

From

COP 1.234.112

Viewed 4 hours ago

Medellin (MDE)to

Santiago de Chile (SCL)

Aug 13, 2026 - Aug 16, 2026

Round trip

Economy

From

COP 1.287.854

Viewed 3 hours ago

Medellin (MDE)to

Cancun (CUN)

Sep 28, 2026 - Oct 01, 2026

Round trip

Economy

From

COP 1.408.746

Viewed 6 hours ago

Medellin (MDE)to

Boston (BOS)

Oct 09, 2026 - Oct 13, 2026

Round trip

Economy

From

COP 1.622.314

Viewed 5 hours ago

Medellin (MDE)to

Mexico City (MEX)

Jul 15, 2026 - Jul 31, 2026

Round trip

Economy

From

COP 1.710.312

Viewed 4 hours ago

Flights from Medellin with Copa Airlines

Depart on a flight from Medellin with Copa Airlines and take advantage of the extensive network of destinations we offer, as well as complimentary drinks and the loyalty program of ConnectMiles, ideal for frequent travelers.

The José María Córdova International Airport

Depart from Medellin at the José María Córdova International Airport (MDE), which is almost an hour away from the city, so take your precautions when you take your flight. This airport operates 24 hours a day and has three restaurants and a commercial area with banking and bureau de change services. Arrive at the airport by taxi, one of the public service buses leaving the San Diego Mall or a rental car.