What is the best fare to fly from Medellin?

The best fare to fly from Medellin starts at **Flights.FromLowestPrice**. Fly with Copa Airlines.

Find Copa Airlines flights from Medellin (MDE) from COP868.104*

1 Passenger

Promo Code

From

Departure

Return

Restrictions apply; please see Terms & Conditions.

Offers on flights from Medellin

From

Budget

COP

Medellin (MDE)to

Panama (PTY)

Mar 11, 2026 - Mar 15, 2026

From

COP915.386

Viewed 20 minutes ago

Round trip

Economy

Medellin (MDE)to

Mexico City (MEX)

Feb 28, 2026 - Mar 15, 2026

From

COP1.587.146

Viewed 1 hour ago

Round trip

Economy

Medellin (MDE)to

Boston (BOS)

Apr 01, 2026 - Apr 09, 2026

From

COP1.374.932

Viewed 1 day ago

Round trip

Economy

Medellin (MDE)to

New York (JFK)

Feb 11, 2026 - Mar 02, 2026

From

COP1.144.612

Viewed 4 hours ago

Round trip

Economy

Medellin (MDE)to

Orlando (MCO)

Mar 25, 2026 - Apr 02, 2026

From

COP1.168.680

Viewed 1 hour ago

Round trip

Economy

Medellin (MDE)to

Buenos Aires (EZE)

May 18, 2026 - May 22, 2026

From

COP2.055.184

Viewed 5 minutes ago

Round trip

Economy

Medellin (MDE)to

Punta Cana (PUJ)

Mar 06, 2026 - Mar 08, 2026

From

COP1.162.978

Viewed 1 hour ago

Round trip

Economy

Medellin (MDE)to

Los Angeles (LAX)

Mar 14, 2026 - Mar 18, 2026

From

COP1.691.650

Viewed 1 day ago

Round trip

Economy

Medellin (MDE)to

Sao Paulo (GRU)

Mar 03, 2026 - Mar 07, 2026

From

COP1.476.192

Viewed 20 minutes ago

Round trip

Economy

Medellin (MDE)to

Miami (MIA)

Feb 11, 2026 - Mar 19, 2026

From

COP1.048.666

Viewed 1 day ago

Round trip

Economy

Medellin (MDE)to

Rio de Janeiro (GIG)

Feb 27, 2026 - Mar 06, 2026

From

COP1.473.292

Viewed 5 hours ago

Round trip

Economy

Medellin (MDE)to

Santiago de Chile (SCL)

Aug 20, 2026 - Sep 05, 2026

From

COP1.650.394

Viewed 1 hour ago

Round trip

Economy

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Best prices on Medellin flights

From

Budget

COP

Medellin (MDE)to

Panama (PTY)

Mar 11, 2026 - Mar 15, 2026

Round trip

Economy

From

COP915.386

Viewed 20 minutes ago

Medellin (MDE)to

Mexico City (MEX)

Mar 05, 2026 - Mar 09, 2026

Round trip

Economy

From

COP1.588.926

Viewed 1 day ago

Medellin (MDE)to

Boston (BOS)

Apr 01, 2026 - Apr 09, 2026

Round trip

Economy

From

COP1.374.932

Viewed 1 day ago

Medellin (MDE)to

Orlando (MCO)

Mar 25, 2026 - Apr 02, 2026

Round trip

Economy

From

COP1.168.680

Viewed 1 hour ago

Medellin (MDE)to

New York (JFK)

Apr 15, 2026 - Apr 19, 2026

Round trip

Economy

From

COP1.213.808

Viewed 1 day ago

Medellin (MDE)to

Rio de Janeiro (GIG)

Mar 17, 2026 - Mar 25, 2026

Round trip

Economy

From

COP1.473.292

Viewed 10 hours ago

Flights from Medellin with Copa Airlines

Depart on a flight from Medellin with Copa Airlines and take advantage of the extensive network of destinations we offer, as well as complimentary drinks and the loyalty program of ConnectMiles, ideal for frequent travelers.

The José María Córdova International Airport

Depart from Medellin at the José María Córdova International Airport (MDE), which is almost an hour away from the city, so take your precautions when you take your flight. This airport operates 24 hours a day and has three restaurants and a commercial area with banking and bureau de change services. Arrive at the airport by taxi, one of the public service buses leaving the San Diego Mall or a rental car.