Find Copa Airlines flights from Medellin (MDE) to Santo Domingo (SDQ) from COP 985.148*

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Best prices on Medellin to Santo Domingo flights

Oct 2026
FromCOP 1.646.978*
Viewed 5 hours ago
Round trip/Economy
Nov 2026
FromCOP 987.682*
Viewed 1 day ago
Round trip/Economy
Dec 2026
FromCOP 985.148*
Viewed 1 hour ago
Round trip/Economy
cmp-daily-histogram-bars-legend-min-price-aria-label COP 987.7K
cmp-daily-histogram-bars-legend-max-price-aria-label COP 2.8M
Displaying fares for October-2026
  • MDE–SDQ: cmp-view-offers-disclaimer. Check availability
    28

    Wed

    OCT

  • MDE–SDQ: cmp-view-offers-disclaimer. Check availability
    29

    Thu

  • MDE–SDQ, Oct 30, 2026 – Nov 02, 2026: From COP 1.651.606
    30

    Fri

  • MDE–SDQ, Oct 31, 2026 – Nov 02, 2026: From COP 1.646.978
    31

    Sat

  • MDE–SDQ, Nov 01, 2026 – Nov 04, 2026: From COP 2.027.003
    01

    Sun

    NOV

  • MDE–SDQ, Nov 02, 2026 – Nov 11, 2026: From COP 1.157.120
    02

    Mon

  • MDE–SDQ, Nov 03, 2026 – Nov 15, 2026: From COP 987.682
    03

    Tue

  • MDE–SDQ: cmp-view-offers-disclaimer. Check availability
    04

    Wed

  • MDE–SDQ: cmp-view-offers-disclaimer. Check availability
    05

    Thu

  • MDE–SDQ, Nov 06, 2026 – Nov 23, 2026: From COP 987.682
    06

    Fri

  • MDE–SDQ, Nov 07, 2026 – Nov 14, 2026: From COP 987.682
    07

    Sat

  • MDE–SDQ, Nov 08, 2026 – Nov 14, 2026: From COP 1.106.981
    08

    Sun

  • MDE–SDQ: cmp-view-offers-disclaimer. Check availability
    09

    Mon

  • MDE–SDQ, Nov 10, 2026 – Nov 14, 2026: From COP 1.019.619
    10

    Tue

  • MDE–SDQ, Nov 11, 2026 – Nov 14, 2026: From COP 987.682
    11

    Wed

  • MDE–SDQ, Nov 12, 2026 – Nov 16, 2026: From COP 2.752.490
    12

    Thu

  • MDE–SDQ: cmp-view-offers-disclaimer. Check availability
    13

    Fri

  • MDE–SDQ, Nov 14, 2026 – Nov 27, 2026: From COP 1.337.035
    14

    Sat

  • MDE–SDQ: cmp-view-offers-disclaimer. Check availability
    15

    Sun

  • MDE–SDQ: cmp-view-offers-disclaimer. Check availability
    16

    Mon

  • MDE–SDQ: cmp-view-offers-disclaimer. Check availability
    17

    Tue

  • MDE–SDQ, Nov 18, 2026 – Nov 30, 2026: From COP 1.425.133
    18

    Wed

  • MDE–SDQ: cmp-view-offers-disclaimer. Check availability
    19

    Thu

  • MDE–SDQ, Nov 20, 2026 – Nov 22, 2026: From COP 1.550.474
    20

    Fri

  • MDE–SDQ, Nov 21, 2026 – Dec 05, 2026: From COP 1.423.749
    21

    Sat

  • MDE–SDQ, Nov 22, 2026 – Nov 26, 2026: From COP 1.106.981
    22

    Sun

  • MDE–SDQ: cmp-view-offers-disclaimer. Check availability
    23

    Mon

  • MDE–SDQ: cmp-view-offers-disclaimer. Check availability
    24

    Tue

  • MDE–SDQ: cmp-view-offers-disclaimer. Check availability
    25

    Wed

  • MDE–SDQ: cmp-view-offers-disclaimer. Check availability
    26

    Thu

  • MDE–SDQ: cmp-view-offers-disclaimer. Check availability
    27

    Fri

    • FromCOP 987.682-COP 2.752.490

    *Restrictions apply; please see Terms & Conditions.

    Round-trip fares from Medellin to Santo Domingo

    COP
    Round-trip fares from Medellin to Santo Domingo
    From
    To
    Fare Type
    Dates
    Price
    Medellin (MDE)Santo Domingo (SDQ)Round trip
    /
    Economy    		Dec 05, 2026 - Dec 10, 2026

    From

    COP 985.148

    Viewed 1 hour ago

    Medellin (MDE)Santo Domingo (SDQ)Round trip
    /
    Economy    		Nov 11, 2026 - Nov 14, 2026

    From

    COP 987.682

    Viewed 1 day ago

    Medellin (MDE)Santo Domingo (SDQ)Round trip
    /
    Economy    		Nov 07, 2026 - Nov 14, 2026

    From

    COP 987.682

    Viewed 20 hours ago

    Medellin (MDE)Santo Domingo (SDQ)Round trip
    /
    Economy    		Dec 04, 2026 - Dec 09, 2026

    From

    COP 989.549

    Viewed 1 day ago

    Medellin (MDE)Santo Domingo (SDQ)Round trip
    /
    Economy    		Nov 06, 2026 - Nov 14, 2026

    From

    COP 987.682

    Viewed 19 hours ago

    *Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
    *Restrictions apply; please see Terms & Conditions.

    Destination facts

    Destination airports
    • Las Américas International Airport (SDQ)
    Copa Airlines hub

    Hub of the Americas® in Panama

    Destination FAQs

    Which country or territory is the destination on this page in?

    Destination country or territory: Dominican Republic.

    How do I identify the arrival airport?

    Check the name and code of the arrival airport in your selected itinerary.

    Where is the Hub of the Americas®?

    Copa Airlines’ Hub of the Americas® is in Panama.

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