Find Copa Airlines flights to Medellin (MDE) from USD 338*

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Fares for flights to Medellin through the Hub of the Americas®,in Panama City

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Guayaquil (GYE)to

Medellin (MDE)
Nov 08, 2026 - Nov 11, 2026
From
USD 338
Viewed 1 day ago
Round trip
Economy

Quito (UIO)to

Medellin (MDE)
Jan 12, 2027 - Jan 20, 2027
From
USD 369
Viewed 58 minutes ago
Round trip
Economy

Manta (MEC)to

Medellin (MDE)
Jan 27, 2027 - Feb 01, 2027
From
USD 475
Viewed 19 hours ago
Round trip
Economy

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Plan your next trip to Medellin with these low fares

USD

Guayaquil (GYE)to

Medellin (MDE)
Nov 09, 2026 - Nov 12, 2026

Round trip

Economy

From
USD 338
Viewed 1 day ago

Quito (UIO)to

Medellin (MDE)
Jan 12, 2027 - Jan 20, 2027

Round trip

Economy

From
USD 369
Viewed 58 minutes ago

Manta (MEC)to

Medellin (MDE)
Jan 27, 2027 - Feb 01, 2027

Round trip

Economy

From
USD 475
Viewed 19 hours ago

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Fly to Medellin with Copa Air

Travel to Medellin with Copa Airlines and discover one of the largest cities in South America, combining the old and the new in its architecture and museums. In addition, it was the birthplace of the artist Fernando Botero.

Explore Medellin

  • Museums: The Antioquia Museum is one of the best known in Colombia and houses a large collection of works of art donated by the painter Botero.
  • Architectural contrasts: On the one hand, there is the romantic style of the Metropolitan Cathedral and on the other, modern buildings such as the Biblioteca España.
  • Contact with nature: You can visit places full of natural life like Explora Park, Barefoot Park and Botanical Garden.
  • Active nights: The nightlife of Medellin is lively and in Lleras Park are many bars and nightclubs where you can spend a fun night. For something more chic, Via de Las Palmas is a wonderful street to explore.

Transportation in Medellín

This modern city has efficient public transport systems. Take the Metro to avoid mishaps with transit or go through some of the Metrocable lines, a public transport by cable car that is seen in few parts of the world. The journey from the airport to the city is long, so book a car from when you purchase your flight to Medellin in copa.com or use the public service buses that connect to the San Diego Mall.