Find Copa Airlines flights from Guayaquil (GYE) to Medellin (MDE) from USD277*
expand_more
expand_more
1 Passenger
expand_morePromo Code
expand_moretoday
today
Restrictions apply; please see Terms & Conditions.
Best prices on Guayaquil to Medellin flights
location_on
location_on
Best airfares from Guayaquil to Medellin flights
flight_takeoff
flight_land
USD
From | To | Fare Type | Dates | Price |
|---|---|---|---|---|
| Guayaquil (GYE) | Medellin (MDE) | Round trip / Economy | Feb 23, 2026 - Feb 28, 2026 | From USD277 Viewed 1 day ago |
| Guayaquil (GYE) | Medellin (MDE) | Round trip / Economy | Jan 19, 2026 - Jan 23, 2026 | From USD277 Viewed 1 day ago |
| Guayaquil (GYE) | Medellin (MDE) | Round trip / Economy | Feb 11, 2026 - Feb 20, 2026 | From USD277 Viewed 21 hours ago |
| Guayaquil (GYE) | Medellin (MDE) | Round trip / Economy | Feb 11, 2026 - Feb 25, 2026 | From USD277 Viewed 19 hours ago |
| Guayaquil (GYE) | Medellin (MDE) | Round trip / Economy | Feb 11, 2026 - Feb 12, 2026 | From USD277 Viewed 1 day ago |
*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.
Our App
Download the Copa Airlines App now and buy tickets, manage your reservations, access to your ConnectMiles account and much more.
Subscribe and save!
Subscribe and be one of the first to know about our exclusive fares, promotions and last minute offers.
Subscribe