Find Copa Airlines flights from Panama (PTY) to Guayaquil (GYE) from USD 417*

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Restrictions apply; please see Terms & Conditions.

Best prices on Panama to Guayaquil flights

Oct 2026
FromUSD 434*
Viewed 11 hours ago
Round trip/Economy
Nov 2026
FromUSD 417*
Viewed 2 hours ago
Round trip/Economy
Dec 2026
FromUSD 452*
Viewed 1 day ago
Round trip/Economy
cmp-daily-histogram-bars-legend-min-price-aria-label USD 417
cmp-daily-histogram-bars-legend-max-price-aria-label USD 878
Displaying fares for October-2026
  • PTY–GYE: cmp-view-offers-disclaimer. Check availability
    11

    Sun

    OCT

  • PTY–GYE, Oct 12, 2026 – Oct 13, 2026: From USD 493
    12

    Mon

  • PTY–GYE, Oct 13, 2026 – Oct 14, 2026: From USD 493
    13

    Tue

  • PTY–GYE: cmp-view-offers-disclaimer. Check availability
    14

    Wed

  • PTY–GYE, Oct 15, 2026 – Oct 31, 2026: From USD 878
    15

    Thu

  • PTY–GYE, Oct 16, 2026 – Oct 18, 2026: From USD 452
    16

    Fri

  • PTY–GYE, Oct 17, 2026 – Oct 17, 2026: From USD 452
    17

    Sat

  • PTY–GYE, Oct 18, 2026 – Oct 20, 2026: From USD 452
    18

    Sun

  • PTY–GYE, Oct 19, 2026 – Oct 24, 2026: From USD 452
    19

    Mon

  • PTY–GYE, Oct 20, 2026 – Oct 23, 2026: From USD 452
    20

    Tue

  • PTY–GYE, Oct 21, 2026 – Oct 23, 2026: From USD 452
    21

    Wed

  • PTY–GYE, Oct 22, 2026 – Oct 23, 2026: From USD 452
    22

    Thu

  • PTY–GYE, Oct 23, 2026 – Nov 08, 2026: From USD 434
    23

    Fri

  • PTY–GYE, Oct 24, 2026 – Nov 07, 2026: From USD 434
    24

    Sat

  • PTY–GYE: cmp-view-offers-disclaimer. Check availability
    25

    Sun

  • PTY–GYE, Oct 26, 2026 – Nov 10, 2026: From USD 434
    26

    Mon

  • PTY–GYE: cmp-view-offers-disclaimer. Check availability
    27

    Tue

  • PTY–GYE: cmp-view-offers-disclaimer. Check availability
    28

    Wed

  • PTY–GYE: cmp-view-offers-disclaimer. Check availability
    29

    Thu

  • PTY–GYE, Oct 30, 2026 – Nov 10, 2026: From USD 434
    30

    Fri

  • PTY–GYE, Oct 31, 2026 – Nov 08, 2026: From USD 434
    31

    Sat

  • PTY–GYE, Nov 01, 2026 – Nov 08, 2026: From USD 434
    01

    Sun

    NOV

  • PTY–GYE: cmp-view-offers-disclaimer. Check availability
    02

    Mon

  • PTY–GYE, Nov 03, 2026 – Nov 08, 2026: From USD 842
    03

    Tue

  • PTY–GYE, Nov 04, 2026 – Nov 25, 2026: From USD 434
    04

    Wed

  • PTY–GYE, Nov 05, 2026 – Nov 25, 2026: From USD 434
    05

    Thu

  • PTY–GYE, Nov 06, 2026 – Nov 14, 2026: From USD 434
    06

    Fri

  • PTY–GYE, Nov 07, 2026 – Nov 08, 2026: From USD 417
    07

    Sat

  • PTY–GYE: cmp-view-offers-disclaimer. Check availability
    08

    Sun

  • PTY–GYE, Nov 09, 2026 – Nov 14, 2026: From USD 434
    09

    Mon

  • PTY–GYE, Nov 10, 2026 – Nov 14, 2026: From USD 434
    10

    Tue

    • FromUSD 417-USD 878

    *Restrictions apply; please see Terms & Conditions.

    Best airfares from Panama to Guayaquil flights

    USD
    Best airfares from Panama to Guayaquil flights
    From
    To
    Fare Type
    Dates
    Price
    Panama (PTY)Guayaquil (GYE)Round trip
    /
    Economy    		Nov 07, 2026 - Nov 08, 2026

    From

    USD 417

    Viewed 2 hours ago

    Panama (PTY)Guayaquil (GYE)Round trip
    /
    Economy    		Nov 06, 2026 - Nov 14, 2026

    From

    USD 434

    Viewed 10 hours ago

    Panama (PTY)Guayaquil (GYE)Round trip
    /
    Economy    		Nov 12, 2026 - Nov 14, 2026

    From

    USD 434

    Viewed 10 hours ago

    Panama (PTY)Guayaquil (GYE)Round trip
    /
    Economy    		Nov 04, 2026 - Nov 25, 2026

    From

    USD 434

    Viewed 1 day ago

    Panama (PTY)Guayaquil (GYE)Round trip
    /
    Economy    		Nov 05, 2026 - Nov 25, 2026

    From

    USD 434

    Viewed 21 hours ago

    *Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
    *Restrictions apply; please see Terms & Conditions.

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