What is the best fare to fly from Panama?

The best fare to fly from Panama starts at **Flights.FromLowestPrice**. Fly with Copa Airlines.

Find Copa Airlines flights from Panama (PTY) from #%#Flights.FromLowestPrice#%#

1 Passenger

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From

Departure

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Restrictions apply; please see Terms & Conditions.

Offers on flights from Panama

From

Budget

USD

Panama (PTY)to

David (DAV)

Oct 23, 2026 - Oct 30, 2026

From

USD 91

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

Managua (MGA)

Nov 05, 2026 - Nov 11, 2026

From

USD 260

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

San José (SJO)

Nov 03, 2026 - Nov 06, 2026

From

USD 267

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

Guatemala (GUA)

Nov 04, 2026 - Nov 11, 2026

From

USD 274

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

Medellin (MDE)

Oct 21, 2026 - Oct 28, 2026

From

USD 276

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

Bogota (BOG)

Nov 11, 2026 - Nov 12, 2026

From

USD 338

Viewed 6 hours ago

Round trip

Economy

Panama (PTY)to

Mexico City (MEX)

Dec 25, 2026 - Dec 27, 2026

From

USD 375

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

Miami (MIA)

Dec 27, 2026 - Jan 07, 2027

From

USD 450

Viewed 6 hours ago

Round trip

Economy

Panama (PTY)to

Caracas (CCS)

Sep 22, 2026 - Nov 12, 2026

From

USD 524

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

Orlando (MCO)

Nov 27, 2026 - Dec 05, 2026

From

USD 599

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

New York (JFK)

Mar 09, 2027 - Mar 22, 2027

From

USD 599

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

Buenos Aires (EZE)

Nov 05, 2026 - Nov 08, 2026

From

USD 614

Viewed 1 day ago

Round trip

Economy

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Best prices on Panama flights

From

Budget

USD

Panama (PTY)to

David (DAV)

Nov 20, 2026 - Nov 24, 2026

Round trip

Economy

From

USD 91

Viewed 1 day ago

Panama (PTY)to

Medellin (MDE)

Feb 16, 2027 - Feb 25, 2027

Round trip

Economy

From

USD 276

Viewed 1 day ago

Panama (PTY)to

Bogota (BOG)

Nov 04, 2026 - Nov 10, 2026

Round trip

Economy

From

USD 338

Viewed 1 day ago

Panama (PTY)to

Miami (MIA)

Dec 27, 2026 - Jan 07, 2027

Round trip

Economy

From

USD 450

Viewed 6 hours ago

Panama (PTY)to

Orlando (MCO)

Nov 23, 2026 - Nov 26, 2026

Round trip

Economy

From

USD 599

Viewed 1 day ago

Panama (PTY)to

New York (JFK)

Jan 22, 2027 - Jan 28, 2027

Round trip

Economy

From

USD 599

Viewed 1 day ago

Flights from Panama with Copa Airlines

Whether you choose to depart from Enrique Malek International Airport (DAV), 6.5 kilometers from the city of David and the closest to the beaches of Bocas del Toro, or from Tocumen International Airport (PTY), 24 kilometers from the Panamanian capital, you can take advantage of dining options and tax-free shopping that both airports offer passengers awaiting their flights. Arrive by shuttle, taxi, or a rental car and get ready to start your t.

Your flight from Panama City with Copa Airlines

Copa Airlines offers you direct flights between both airports in Panama, as well as access to its network of international destinations throughout the Americas from the Tocumen International Airport (PTY), the Hub of the Americas.