What is the best fare to fly from Panama?

The best fare to fly from Panama starts at **Flights.FromLowestPrice**. Fly with Copa Airlines.

Find Copa Airlines flights from Panama (PTY) from #%#Flights.FromLowestPrice#%#

1 Passenger

Promo Code

From

Departure

Return

Restrictions apply; please see Terms & Conditions.

Offers on flights from Panama

From

Budget

USD

Panama (PTY)to

David (DAV)

Sep 11, 2026 - Sep 13, 2026

From

USD 85

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

Guatemala (GUA)

Oct 16, 2026 - Oct 23, 2026

From

USD 246

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

Medellin (MDE)

Jul 21, 2026 - Jul 24, 2026

From

USD 276

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

San José (SJO)

Jul 29, 2026 - Aug 01, 2026

From

USD 282

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

Bogota (BOG)

Oct 23, 2026 - Oct 26, 2026

From

USD 351

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

Miami (MIA)

Jul 08, 2026 - Jul 19, 2026

From

USD 389

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

Mexico City (MEX)

Jul 10, 2026 - Jul 12, 2026

From

USD 405

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

Lima (LIM)

Sep 17, 2026 - Sep 27, 2026

From

USD 475

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

Orlando (MCO)

Jul 06, 2026 - Jul 15, 2026

From

USD 515

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

New York (JFK)

Aug 17, 2026 - Aug 31, 2026

From

USD 549

Viewed 23 hours ago

Round trip

Economy

Panama (PTY)to

Toronto (YYZ)

Jul 03, 2026 - Jul 05, 2026

From

USD 626

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

Santiago de Chile (SCL)

Nov 06, 2026 - Nov 14, 2026

From

USD 658

Viewed 1 day ago

Round trip

Economy

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Best prices on Panama flights

From

Budget

USD

Panama (PTY)to

David (DAV)

Sep 01, 2026 - Sep 07, 2026

Round trip

Economy

From

USD 85

Viewed 1 day ago

Panama (PTY)to

Medellin (MDE)

Nov 17, 2026 - Nov 20, 2026

Round trip

Economy

From

USD 276

Viewed 1 day ago

Panama (PTY)to

Bogota (BOG)

Jul 28, 2026 - Jul 30, 2026

Round trip

Economy

From

USD 351

Viewed 1 day ago

Panama (PTY)to

Miami (MIA)

Aug 21, 2026 - Sep 04, 2026

Round trip

Economy

From

USD 411

Viewed 1 day ago

Panama (PTY)to

Mexico City (MEX)

Jul 16, 2026 - Jul 31, 2026

Round trip

Economy

From

USD 412

Viewed 6 hours ago

Panama (PTY)to

New York (JFK)

Aug 17, 2026 - Aug 31, 2026

Round trip

Economy

From

USD 549

Viewed 23 hours ago

Flights from Panama with Copa Airlines

Whether you choose to depart from Enrique Malek International Airport (DAV), 6.5 kilometers from the city of David and the closest to the beaches of Bocas del Toro, or from Tocumen International Airport (PTY), 24 kilometers from the Panamanian capital, you can take advantage of dining options and tax-free shopping that both airports offer passengers awaiting their flights. Arrive by shuttle, taxi, or a rental car and get ready to start your t.

Your flight from Panama City with Copa Airlines

Copa Airlines offers you direct flights between both airports in Panama, as well as access to its network of international destinations throughout the Americas from the Tocumen International Airport (PTY), the Hub of the Americas.