What is the best fare to fly from Panama?

The best fare to fly from Panama starts at **Flights.FromLowestPrice**. Fly with Copa Airlines.

Find Copa Airlines flights from Panama (PTY) from USD85*

1 Passenger

Promo Code

From

Departure

Return

Restrictions apply; please see Terms & Conditions.

Offers on flights from Panama

From

Budget

USD

Panama (PTY)to

Miami (MIA)

May 31, 2026 - Jun 07, 2026

From

USD371

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

Medellin (MDE)

Feb 03, 2026 - Feb 11, 2026

From

USD237

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

Bogota (BOG)

Feb 22, 2026 - Feb 26, 2026

From

USD212

Viewed 22 hours ago

Round trip

Economy

Panama (PTY)to

David (DAV)

Feb 01, 2026 - Feb 28, 2026

From

USD85

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

Orlando (MCO)

May 09, 2026 - May 16, 2026

From

USD441

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

San José (SJO)

Mar 09, 2026 - Mar 11, 2026

From

USD225

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

Caracas (CCS)

Feb 20, 2026 - Apr 28, 2026

From

USD559

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

Mexico City (MEX)

Feb 10, 2026 - Feb 25, 2026

From

USD352

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

New York (JFK)

May 27, 2026 - Jun 01, 2026

From

USD514

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

Cartagena (CTG)

Sep 07, 2026 - Sep 12, 2026

From

USD317

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

Cancun (CUN)

Feb 04, 2026 - Feb 10, 2026

From

USD331

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

Barranquilla (BAQ)

Feb 02, 2026 - Mar 01, 2026

From

USD246

Viewed 1 day ago

Round trip

Economy

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Best prices on Panama flights

From

Budget

USD

Panama (PTY)to

Miami (MIA)

Apr 05, 2026 - Apr 11, 2026

Round trip

Economy

From

USD371

Viewed 1 day ago

Panama (PTY)to

Medellin (MDE)

Mar 25, 2026 - Mar 31, 2026

Round trip

Economy

From

USD237

Viewed 1 day ago

Panama (PTY)to

Bogota (BOG)

Mar 02, 2026 - Mar 06, 2026

Round trip

Economy

From

USD212

Viewed 22 hours ago

Panama (PTY)to

David (DAV)

Mar 04, 2026 - Mar 06, 2026

Round trip

Economy

From

USD85

Viewed 1 day ago

Panama (PTY)to

Orlando (MCO)

May 13, 2026 - May 20, 2026

Round trip

Economy

From

USD441

Viewed 1 day ago

Panama (PTY)to

Mexico City (MEX)

Apr 13, 2026 - Apr 24, 2026

Round trip

Economy

From

USD352

Viewed 1 day ago

Flights from Panama with Copa Airlines

Whether you choose to depart from Enrique Malek International Airport (DAV), 6.5 kilometers from the city of David and the closest to the beaches of Bocas del Toro, or from Tocumen International Airport (PTY), 24 kilometers from the Panamanian capital, you can take advantage of dining options and tax-free shopping that both airports offer passengers awaiting their flights. Arrive by shuttle, taxi, or a rental car and get ready to start your t.

Your flight from Panama City with Copa Airlines

Copa Airlines offers you direct flights between both airports in Panama, as well as access to its network of international destinations throughout the Americas from the Tocumen International Airport (PTY), the Hub of the Americas.