Find Copa Airlines flights to Santo Domingo (SDQ) from USD361*

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Restrictions apply; please see Terms & Conditions.

Fares for flights to Santo Domingo through the Hub of the Americas®,in Panama City

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Tampa (TPA)to

Santo Domingo (SDQ)
Oct 06, 2026 - Oct 13, 2026
From
USD369
Viewed 23 hours ago
Round trip
Economy

Orlando (MCO)to

Santo Domingo (SDQ)
Apr 18, 2026 - Apr 22, 2026
From
USD407
Viewed 1 day ago
Round trip
Economy

Washington Dulles (IAD)to

Santo Domingo (SDQ)
Apr 22, 2026 - Apr 27, 2026
From
USD447
Viewed 22 hours ago
Round trip
Economy

Los Angeles (LAX)to

Santo Domingo (SDQ)
May 01, 2026 - May 09, 2026
From
USD614
Viewed 1 day ago
Round trip
Economy

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Plan your next trip to Santo Domingo with these low fares

USD

Tampa (TPA)to

Santo Domingo (SDQ)
May 07, 2026 - May 12, 2026

Round trip

Economy

From
USD369
Viewed 11 minutes ago

Orlando (MCO)to

Santo Domingo (SDQ)
Apr 18, 2026 - Apr 22, 2026

Round trip

Economy

From
USD407
Viewed 1 day ago

Washington Dulles (IAD)to

Santo Domingo (SDQ)
Apr 18, 2026 - Apr 21, 2026

Round trip

Economy

From
USD447
Viewed 1 day ago

San Diego (SAN)to

Santo Domingo (SDQ)
May 15, 2026 - May 25, 2026

Round trip

Economy

From
USD469
Viewed 1 day ago

Los Angeles (LAX)to

Santo Domingo (SDQ)
May 01, 2026 - May 09, 2026

Round trip

Economy

From
USD614
Viewed 1 day ago

Boston (BOS)to

Santo Domingo (SDQ)
Jun 13, 2026 - Jun 26, 2026

Round trip

Economy

From
USD702
Viewed 19 hours ago

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Fly to Santo Domingo with Copa Air

The oldest city of the New World is Santo Domingo. Here you can find historic evidence that drastically contrasts with the modern dance clubs and cafes fond in the pier. Fly to Santo Domingo and discover this city with Copa Airlines.

What can you do in Santo Domingo?

  • Night life: you can dance a nice merengue at discos and clubs. Also, you can spend a funny and entertaining night at one of the casinos in the city.
  • Shopping: Dominican amber and other local products can be found in the Modelo Market, which is the national one. Additionally, you can find malls in the center of the city, which is a much modern option.
  • Historic attractions: being such an old city, there are constructions like Columbus Alcazar and the Cathedral called Primate of the Americas, which represent a must-see in your trip to Santo Domingo.

Transportation in Santo Domingo

There’s a convenient subway system that is really fast and efficient, as well as cheap. You can also get a taxi, just keep in mind that collective transportation is very popular around the city. Remember that when you fly to Santo Domingo with Copa Airlines, you can make reservations for renting a car that gets you around Santo Domingo on our website at copa.com