Find Copa Airlines flights from San Francisco (SFO) to Santo Domingo (SDQ) from USD500*

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Restrictions apply; please see Terms & Conditions.

Best prices on San Francisco to Santo Domingo flights

Apr 2026
FromUSD704*
Viewed 21 hours ago
Round trip/Economy
May 2026
FromUSD647*
Viewed 21 hours ago
Round trip/Economy
Jun 2026
FromUSD786*
Viewed 1 day ago
Round trip/Economy
USD647
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    • FromUSD647-USD748

    *Restrictions apply; please see Terms & Conditions.

    Best airfares from San Francisco to Santo Domingo flights

    USD
    Best airfares from San Francisco to Santo Domingo flights
    From
    To
    Fare Type
    Dates
    Price
    San Francisco (SFO)Santo Domingo (SDQ)Round trip
    /
    Economy    		Sep 01, 2026 - Sep 08, 2026

    From

    USD500

    Viewed 5 hours ago

    San Francisco (SFO)Santo Domingo (SDQ)Round trip
    /
    Economy    		Apr 22, 2026 - Apr 30, 2026

    From

    USD748

    Viewed 1 hour ago

    San Francisco (SFO)Santo Domingo (SDQ)Round trip
    /
    Economy    		May 02, 2026 - May 13, 2026

    From

    USD647

    Viewed 21 hours ago

    San Francisco (SFO)Santo Domingo (SDQ)Round trip
    /
    Economy    		May 10, 2026 - May 21, 2026

    From

    USD647

    Viewed 1 day ago

    San Francisco (SFO)Santo Domingo (SDQ)Round trip
    /
    Economy    		Apr 29, 2026 - May 13, 2026

    From

    USD704

    Viewed 21 hours ago

    *Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
    *Restrictions apply; please see Terms & Conditions.

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