What is the best fare to fly from Santa Cruz?

The best fare to fly from Santa Cruz starts at **Flights.FromLowestPrice**. Fly with Copa Airlines.

Find Copa Airlines flights from Santa Cruz (VVI) from USD445*

1 Passenger

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From

Departure

Return

Restrictions apply; please see Terms & Conditions.

Offers on flights from Santa Cruz

From

Budget

USD

Santa Cruz (VVI)to

Washington Dulles (IAD)

Oct 11, 2025 - Nov 16, 2025

From

USD547

Viewed 1 day ago

Round trip
/
Economy

Santa Cruz (VVI)to

Miami (MIA)

Sep 25, 2025 - Oct 10, 2025

From

USD445

Viewed 1 day ago

Round trip
/
Economy

Santa Cruz (VVI)to

Mexico City (MEX)

Sep 18, 2025 - Oct 08, 2025

From

USD537

Viewed 22 hours ago

Round trip
/
Economy

Santa Cruz (VVI)to

Panama (PTY)

Nov 14, 2025 - Nov 26, 2025

From

USD531

Viewed 1 day ago

Round trip
/
Economy

Santa Cruz (VVI)to

New York (JFK)

Nov 25, 2025 - Jan 20, 2026

From

USD518

Viewed 1 day ago

Round trip
/
Economy

Santa Cruz (VVI)to

Orlando (MCO)

Sep 29, 2025 - Oct 06, 2025

From

USD702

Viewed 1 day ago

Round trip
/
Economy

Santa Cruz (VVI)to

San José (SJO)

Dec 13, 2025 - Jan 11, 2026

From

USD616

Viewed 1 day ago

Round trip
/
Economy

Santa Cruz (VVI)to

Boston (BOS)

Oct 20, 2025 - Oct 21, 2025

From

USD518

Viewed 1 day ago

Round trip
/
Economy

Santa Cruz (VVI)to

Los Angeles (LAX)

Jan 29, 2026 - Feb 13, 2026

From

USD794

Viewed 1 day ago

Round trip
/
Economy

Santa Cruz (VVI)to

Punta Cana (PUJ)

Sep 26, 2025 - Oct 05, 2025

From

USD723

Viewed 16 hours ago

Round trip
/
Economy

Santa Cruz (VVI)to

Havana (HAV)

Oct 03, 2025 - Oct 10, 2025

From

USD505

Viewed 1 day ago

Round trip
/
Economy

Santa Cruz (VVI)to

Cancun (CUN)

Sep 18, 2025 - Sep 24, 2025

From

USD648

Viewed 1 day ago

Round trip
/
Economy

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Best prices on Santa Cruz flights

From

Budget

USD

Santa Cruz (VVI)to
Washington Dulles (IAD)
Oct 19, 2025 - Oct 20, 2025
Round trip
/
Economy

From
USD547*
Viewed 1 day ago

Santa Cruz (VVI)to
Miami (MIA)
Oct 26, 2025 - Oct 31, 2025
Round trip
/
Economy

From
USD445*
Viewed 1 day ago

Santa Cruz (VVI)to
Mexico City (MEX)
Oct 16, 2025 - Oct 25, 2025
Round trip
/
Economy

From
USD537*
Viewed 10 hours ago

Santa Cruz (VVI)to
Panama (PTY)
Nov 21, 2025 - Dec 02, 2025
Round trip
/
Economy

From
USD531*
Viewed 1 day ago

Santa Cruz (VVI)to
New York (JFK)
Oct 27, 2025 - Nov 03, 2025
Round trip
/
Economy

From
USD518*
Viewed 1 day ago

Santa Cruz (VVI)to
Orlando (MCO)
Nov 24, 2025 - Dec 31, 2025
Round trip
/
Economy

From
USD702*
Viewed 1 day ago

Flights from Santa Cruz with Copa Airlines

Through its Hub of the Americas, Copa Airlines offers flights from Santa Cruz to more than 60 destinations in the Americas. In addition, your ability to manage the details of your booking online will allow you to enjoy a first-class experience from the moment your purchase your ticket.

Departing from the international airport of Santa Cruz

Viru Viru International Airport (VVI) is located 13 km north of the city centre. The cheapest way to get there is to take a shuttle from the center of the city. The shuttles operate from 5 AM to 8 PM and have space for luggage. Depending on your flight schedule, it is likely that you will need to take a taxi, which are available 24 hours. The airport has several restaurants and coffee shops so that you can relax before boarding. You can also take advantage of the time to shop at the duty-free store.

Travel from Santa Cruz with Copa Airlines

Copa Airlines has one of the newest fleets in the region and provides numerous options for entertainment, movies and music so that your flight from Santa Cruz will be enjoyable. Book your ticket today!