What is the best fare to fly from Santa Cruz?

The best fare to fly from Santa Cruz starts at **Flights.FromLowestPrice**. Fly with Copa Airlines.

Find Copa Airlines flights from Santa Cruz (VVI) from USD 784*

1 Passenger

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Restrictions apply; please see Terms & Conditions.

Round-trip flights from Santa Cruz

From

Budget

USD

Santa Cruz (VVI)to

Miami (MIA)

Feb 11, 2027 - Mar 01, 2027

From

USD 662

Viewed 1 day ago

Round trip

Economy

Santa Cruz (VVI)to

Caracas (CCS)

Nov 09, 2026 - Nov 13, 2026

From

USD 679

Viewed 19 hours ago

Round trip

Economy

Santa Cruz (VVI)to

San José (SJO)

Apr 15, 2027 - Apr 22, 2027

From

USD 703

Viewed 1 day ago

Round trip

Economy

Santa Cruz (VVI)to

Washington Dulles (IAD)

Nov 04, 2026 - Nov 20, 2026

From

USD 765

Viewed 1 day ago

Round trip

Economy

Santa Cruz (VVI)to

Panama (PTY)

Jan 11, 2027 - Jan 18, 2027

From

USD 784

Viewed 1 day ago

Round trip

Economy

Santa Cruz (VVI)to

Punta Cana (PUJ)

Nov 17, 2026 - Nov 22, 2026

From

USD 793

Viewed 8 hours ago

Round trip

Economy

Santa Cruz (VVI)to

Cancun (CUN)

Feb 15, 2027 - Feb 23, 2027

From

USD 802

Viewed 1 day ago

Round trip

Economy

Santa Cruz (VVI)to

Boston (BOS)

Nov 11, 2026 - Nov 17, 2026

From

USD 806

Viewed 1 day ago

Round trip

Economy

Santa Cruz (VVI)to

Los Angeles (LAX)

Nov 27, 2026 - Dec 30, 2026

From

USD 848

Viewed 1 day ago

Round trip

Economy

Santa Cruz (VVI)to

Mexico City (MEX)

Mar 25, 2027 - Apr 08, 2027

From

USD 865

Viewed 1 day ago

Round trip

Economy

Santa Cruz (VVI)to

New York (JFK)

Feb 17, 2027 - Feb 21, 2027

From

USD 917

Viewed 15 hours ago

Round trip

Economy

Santa Cruz (VVI)to

Fort Lauderdale (FLL)

Dec 05, 2026 - Dec 11, 2026

From

USD 1,125

Viewed 21 hours ago

Round trip

Economy

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Round-trip fares from Santa Cruz

From

Budget

USD

Santa Cruz (VVI)to

Miami (MIA)

Feb 11, 2027 - Mar 01, 2027

Round trip

Economy

From

USD 662

Viewed 1 day ago

Santa Cruz (VVI)to

San José (SJO)

Feb 01, 2027 - Mar 02, 2027

Round trip

Economy

From

USD 703

Viewed 12 hours ago

Santa Cruz (VVI)to

Washington Dulles (IAD)

Jan 31, 2027 - May 30, 2027

Round trip

Economy

From

USD 765

Viewed 17 hours ago

Santa Cruz (VVI)to

Panama (PTY)

Dec 01, 2026 - Jan 24, 2027

Round trip

Economy

From

USD 784

Viewed 1 day ago

Santa Cruz (VVI)to

Cancun (CUN)

Feb 21, 2027 - Feb 23, 2027

Round trip

Economy

From

USD 802

Viewed 1 day ago

Santa Cruz (VVI)to

Mexico City (MEX)

Apr 24, 2027 - May 02, 2027

Round trip

Economy

From

USD 865

Viewed 10 hours ago

Flights from Santa Cruz with Copa Airlines

Through its Hub of the Americas, Copa Airlines offers flights from Santa Cruz to more than 60 destinations in the Americas. In addition, your ability to manage the details of your booking online will allow you to enjoy a first-class experience from the moment your purchase your ticket.

Departing from the international airport of Santa Cruz

Viru Viru International Airport (VVI) is located 13 km north of the city centre. The cheapest way to get there is to take a shuttle from the center of the city. The shuttles operate from 5 AM to 8 PM and have space for luggage. Depending on your flight schedule, it is likely that you will need to take a taxi, which are available 24 hours. The airport has several restaurants and coffee shops so that you can relax before boarding. You can also take advantage of the time to shop at the duty-free store.

Travel from Santa Cruz with Copa Airlines

Copa Airlines has one of the newest fleets in the region and provides numerous options for entertainment, movies and music so that your flight from Santa Cruz will be enjoyable. Book your ticket today!