What is the best fare to fly from Santa Cruz?

The best fare to fly from Santa Cruz starts at **Flights.FromLowestPrice**. Fly with Copa Airlines.

Find Copa Airlines flights from Santa Cruz (VVI) from USD 782*

1 Passenger

Promo Code

From

Departure

Return

Restrictions apply; please see Terms & Conditions.

Offers on flights from Santa Cruz

From

Budget

USD

Santa Cruz (VVI)to

Miami (MIA)

Oct 01, 2026 - Oct 19, 2026

From

USD 585

Viewed 1 day ago

Round trip

Economy

Santa Cruz (VVI)to

Havana (HAV)

Oct 05, 2026 - Oct 21, 2026

From

USD 646

Viewed 12 hours ago

Round trip

Economy

Santa Cruz (VVI)to

Caracas (CCS)

Oct 21, 2026 - Oct 28, 2026

From

USD 650

Viewed 22 hours ago

Round trip

Economy

Santa Cruz (VVI)to

Chicago (ORD)

May 12, 2027 - May 25, 2027

From

USD 716

Viewed 1 day ago

Round trip

Economy

Santa Cruz (VVI)to

Punta Cana (PUJ)

Dec 19, 2026 - Dec 26, 2026

From

USD 722

Viewed 1 day ago

Round trip

Economy

Santa Cruz (VVI)to

Washington Dulles (IAD)

Oct 23, 2026 - Nov 06, 2026

From

USD 739

Viewed 1 day ago

Round trip

Economy

Santa Cruz (VVI)to

Boston (BOS)

Nov 03, 2026 - Nov 17, 2026

From

USD 758

Viewed 1 day ago

Round trip

Economy

Santa Cruz (VVI)to

Cancun (CUN)

May 15, 2027 - May 19, 2027

From

USD 777

Viewed 1 day ago

Round trip

Economy

Santa Cruz (VVI)to

Panama (PTY)

Oct 11, 2026 - Jan 11, 2027

From

USD 782

Viewed 1 day ago

Round trip

Economy

Santa Cruz (VVI)to

Mexico City (MEX)

Sep 24, 2026 - Sep 26, 2026

From

USD 782

Viewed 1 day ago

Round trip

Economy

Santa Cruz (VVI)to

Los Angeles (LAX)

Oct 11, 2026 - Nov 01, 2026

From

USD 822

Viewed 1 day ago

Round trip

Economy

Santa Cruz (VVI)to

New York (JFK)

May 26, 2027 - Jun 02, 2027

From

USD 868

Viewed 1 day ago

Round trip

Economy

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Best prices on Santa Cruz flights

From

Budget

USD

Santa Cruz (VVI)to

Miami (MIA)

Oct 25, 2026 - Nov 10, 2026

Round trip

Economy

From

USD 585

Viewed 23 hours ago

Santa Cruz (VVI)to

Washington Dulles (IAD)

Oct 24, 2026 - Nov 11, 2026

Round trip

Economy

From

USD 739

Viewed 1 day ago

Santa Cruz (VVI)to

Panama (PTY)

Nov 12, 2026 - Nov 15, 2026

Round trip

Economy

From

USD 782

Viewed 22 hours ago

Santa Cruz (VVI)to

Mexico City (MEX)

Oct 14, 2026 - Oct 26, 2026

Round trip

Economy

From

USD 782

Viewed 1 day ago

Santa Cruz (VVI)to

Los Angeles (LAX)

Mar 07, 2027 - Mar 28, 2027

Round trip

Economy

From

USD 854

Viewed 11 hours ago

Santa Cruz (VVI)to

New York (JFK)

Nov 06, 2026 - Nov 11, 2026

Round trip

Economy

From

USD 868

Viewed 1 day ago

Flights from Santa Cruz with Copa Airlines

Through its Hub of the Americas, Copa Airlines offers flights from Santa Cruz to more than 60 destinations in the Americas. In addition, your ability to manage the details of your booking online will allow you to enjoy a first-class experience from the moment your purchase your ticket.

Departing from the international airport of Santa Cruz

Viru Viru International Airport (VVI) is located 13 km north of the city centre. The cheapest way to get there is to take a shuttle from the center of the city. The shuttles operate from 5 AM to 8 PM and have space for luggage. Depending on your flight schedule, it is likely that you will need to take a taxi, which are available 24 hours. The airport has several restaurants and coffee shops so that you can relax before boarding. You can also take advantage of the time to shop at the duty-free store.

Travel from Santa Cruz with Copa Airlines

Copa Airlines has one of the newest fleets in the region and provides numerous options for entertainment, movies and music so that your flight from Santa Cruz will be enjoyable. Book your ticket today!