What is the best fare to fly from Santa Cruz?

The best fare to fly from Santa Cruz starts at **Flights.FromLowestPrice**. Fly with Copa Airlines.

Find Copa Airlines flights from Santa Cruz (VVI) from USD 760*

1 Passenger

Promo Code

From

Departure

Return

Restrictions apply; please see Terms & Conditions.

Offers on flights from Santa Cruz

From

Budget

USD

Santa Cruz (VVI)to

Cartagena (CTG)

Sep 08, 2026 - Sep 11, 2026

From

USD 561

Viewed 19 hours ago

Round trip

Economy

Santa Cruz (VVI)to

Havana (HAV)

Aug 25, 2026 - Sep 04, 2026

From

USD 649

Viewed 1 day ago

Round trip

Economy

Santa Cruz (VVI)to

Miami (MIA)

Sep 22, 2026 - Sep 28, 2026

From

USD 661

Viewed 26 minutes ago

Round trip

Economy

Santa Cruz (VVI)to

Mexico City (MEX)

Oct 24, 2026 - Oct 31, 2026

From

USD 691

Viewed 42 minutes ago

Round trip

Economy

Santa Cruz (VVI)to

Punta Cana (PUJ)

Aug 07, 2026 - Aug 21, 2026

From

USD 702

Viewed 4 hours ago

Round trip

Economy

Santa Cruz (VVI)to

Cancun (CUN)

Sep 26, 2026 - Sep 30, 2026

From

USD 719

Viewed 17 hours ago

Round trip

Economy

Santa Cruz (VVI)to

Boston (BOS)

Sep 24, 2026 - Oct 25, 2026

From

USD 738

Viewed 19 hours ago

Round trip

Economy

Santa Cruz (VVI)to

Panama (PTY)

Sep 23, 2026 - Sep 28, 2026

From

USD 760

Viewed 38 minutes ago

Round trip

Economy

Santa Cruz (VVI)to

Washington Dulles (IAD)

Nov 07, 2026 - Nov 14, 2026

From

USD 827

Viewed 20 hours ago

Round trip

Economy

Santa Cruz (VVI)to

Atlanta (ATL)

Oct 29, 2026 - Nov 02, 2026

From

USD 846

Viewed 1 day ago

Round trip

Economy

Santa Cruz (VVI)to

Los Angeles (LAX)

Sep 02, 2026 - Oct 12, 2026

From

USD 847

Viewed 1 day ago

Round trip

Economy

Santa Cruz (VVI)to

New York (JFK)

Sep 29, 2026 - Oct 19, 2026

From

USD 871

Viewed 1 day ago

Round trip

Economy

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Best prices on Santa Cruz flights

From

Budget

USD

Santa Cruz (VVI)to

Miami (MIA)

Sep 22, 2026 - Sep 28, 2026

Round trip

Economy

From

USD 661

Viewed 26 minutes ago

Santa Cruz (VVI)to

Mexico City (MEX)

Oct 24, 2026 - Oct 31, 2026

Round trip

Economy

From

USD 691

Viewed 42 minutes ago

Santa Cruz (VVI)to

Punta Cana (PUJ)

Nov 24, 2026 - Dec 01, 2026

Round trip

Economy

From

USD 702

Viewed 15 hours ago

Santa Cruz (VVI)to

Boston (BOS)

Sep 22, 2026 - Oct 22, 2026

Round trip

Economy

From

USD 738

Viewed 20 hours ago

Santa Cruz (VVI)to

Panama (PTY)

Sep 23, 2026 - Sep 28, 2026

Round trip

Economy

From

USD 760

Viewed 38 minutes ago

Santa Cruz (VVI)to

Washington Dulles (IAD)

Nov 09, 2026 - Nov 18, 2026

Round trip

Economy

From

USD 827

Viewed 1 day ago

Flights from Santa Cruz with Copa Airlines

Through its Hub of the Americas, Copa Airlines offers flights from Santa Cruz to more than 60 destinations in the Americas. In addition, your ability to manage the details of your booking online will allow you to enjoy a first-class experience from the moment your purchase your ticket.

Departing from the international airport of Santa Cruz

Viru Viru International Airport (VVI) is located 13 km north of the city centre. The cheapest way to get there is to take a shuttle from the center of the city. The shuttles operate from 5 AM to 8 PM and have space for luggage. Depending on your flight schedule, it is likely that you will need to take a taxi, which are available 24 hours. The airport has several restaurants and coffee shops so that you can relax before boarding. You can also take advantage of the time to shop at the duty-free store.

Travel from Santa Cruz with Copa Airlines

Copa Airlines has one of the newest fleets in the region and provides numerous options for entertainment, movies and music so that your flight from Santa Cruz will be enjoyable. Book your ticket today!