Find Copa Airlines flights to Santo Domingo (SDQ) from USD259*

Promo Code

Restrictions apply; please see Terms & Conditions.

Fares for flights to Santo Domingo through the Hub of the Americas®,in Panama City

USD

Panama (PTY)to

Santo Domingo (SDQ)
Jan 03, 2026 - Mar 31, 2026
From
USD453
Viewed 1 day ago
Round trip
Economy

Santiago de Chile (SCL)to

Santo Domingo (SDQ)
Nov 07, 2025 - Nov 11, 2025
From
USD478
Viewed 1 day ago
Round trip
Economy

San José (SJO)to

Santo Domingo (SDQ)
Feb 11, 2026 - Feb 15, 2026
From
USD259
Viewed 1 day ago
Round trip
Economy

Guatemala (GUA)to

Santo Domingo (SDQ)
Jan 12, 2026 - Jan 22, 2026
From
USD301
Viewed 1 day ago
Round trip
Economy

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Plan your next trip to Santo Domingo with these low fares

USD

Panama (PTY)to

Santo Domingo (SDQ)
Dec 17, 2025 - Dec 22, 2025

Round trip

Economy

From
USD453
Viewed 1 day ago

Santiago de Chile (SCL)to

Santo Domingo (SDQ)
Dec 03, 2025 - Dec 12, 2025

Round trip

Economy

From
USD559
Viewed 1 day ago

San José (SJO)to

Santo Domingo (SDQ)
Feb 15, 2026 - Feb 24, 2026

Round trip

Economy

From
USD259
Viewed 1 day ago

Guatemala (GUA)to

Santo Domingo (SDQ)
Feb 19, 2026 - Feb 23, 2026

Round trip

Economy

From
USD301
Viewed 1 day ago

Guayaquil (GYE)to

Santo Domingo (SDQ)
Dec 22, 2025 - Dec 25, 2025

Round trip

Economy

From
USD418
Viewed 1 day ago

Buenos Aires (EZE)to

Santo Domingo (SDQ)
Mar 02, 2026 - Mar 21, 2026

Round trip

Economy

From
USD772
Viewed 1 day ago

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Fly to Santo Domingo with Copa Air

The oldest city of the New World is Santo Domingo. Here you can find historic evidence that drastically contrasts with the modern dance clubs and cafes fond in the pier. Fly to Santo Domingo and discover this city with Copa Airlines.

What can you do in Santo Domingo?

  • Night life: you can dance a nice merengue at discos and clubs. Also, you can spend a funny and entertaining night at one of the casinos in the city.
  • Shopping: Dominican amber and other local products can be found in the Modelo Market, which is the national one. Additionally, you can find malls in the center of the city, which is a much modern option.
  • Historic attractions: being such an old city, there are constructions like Columbus Alcazar and the Cathedral called Primate of the Americas, which represent a must-see in your trip to Santo Domingo.

Transportation in Santo Domingo

There’s a convenient subway system that is really fast and efficient, as well as cheap. You can also get a taxi, just keep in mind that collective transportation is very popular around the city. Remember that when you fly to Santo Domingo with Copa Airlines, you can make reservations for renting a car that gets you around Santo Domingo on our website at copa.com