Find Copa Airlines flights to Santa Cruz (VVI) from USD 496*

Promo Code

Restrictions apply; please see Terms & Conditions.

Fares for flights to Santa Cruz through the Hub of the Americas®,in Panama City

USD
sort
keyboard_arrow_down

Havana (HAV)to

Santa Cruz (VVI)
Jun 15, 2026 - Sep 13, 2026
From
USD 565
Viewed 1 day ago
Round trip
Economy

Miami (MIA)to

Santa Cruz (VVI)
Jun 11, 2026 - Jun 15, 2026
From
USD 578
Viewed 1 day ago
Round trip
Economy

Washington Dulles (IAD)to

Santa Cruz (VVI)
Aug 23, 2026 - Sep 15, 2026
From
USD 626
Viewed 17 hours ago
Round trip
Economy

New York (JFK)to

Santa Cruz (VVI)
Sep 15, 2026 - Oct 12, 2026
From
USD 648
Viewed 1 day ago
Round trip
Economy

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Plan your next trip to Santa Cruz with these low fares

USD

Panama (PTY)to

Santa Cruz (VVI)
Jun 18, 2026 - Jun 23, 2026

Round trip

Economy

From
USD 512
Viewed 1 day ago

Havana (HAV)to

Santa Cruz (VVI)
Aug 24, 2026 - Aug 28, 2026

Round trip

Economy

From
USD 565
Viewed 1 day ago

Miami (MIA)to

Santa Cruz (VVI)
Sep 02, 2026 - Sep 07, 2026

Round trip

Economy

From
USD 578
Viewed 1 day ago

Washington Dulles (IAD)to

Santa Cruz (VVI)
Oct 28, 2026 - Nov 06, 2026

Round trip

Economy

From
USD 626
Viewed 1 day ago

New York (JFK)to

Santa Cruz (VVI)
Sep 15, 2026 - Oct 12, 2026

Round trip

Economy

From
USD 648
Viewed 1 day ago

Los Angeles (LAX)to

Santa Cruz (VVI)
Aug 05, 2026 - Aug 31, 2026

Round trip

Economy

From
USD 818
Viewed 1 day ago

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Fly to Santa Cruz with Copa Air

Santa Cruz receives a third of Bolivia's tourists, attracted by its cultural capital and its entertainment and relaxation activities. Copa Airlines offers flights to Santa Cruz from different parts of the Americas.

What to visit in Santa Cruz?

  • Colonial footprints: the Plaza 24 de Septiembre, located in the city center, is surrounded by buildings dating back to the colonial era, such as the Metropolitan Cathedral, City Hall, and the Cultural Center.
  • Outings in the fresh air: surrounding the city are numerous nature reserves where you can discover the local flora and fauna, participate in outdoor actives, and relax. The most popular are Las Lomas de Arena Regional Park, the Güembé Biocenter, and the Ivaga Guazú Ecological Park.
  • Go shopping: Santa Cruz boasts malls and shops with domestic and imported items, where you can buy a variety of products and gifts.

Getting around Santa Cruz

The simplest way of touring the city is to use some of the 132 urban bus routes. You can also rent a car or take a taxi to reach more remote destinations. Thanks to the excellent service aboard Copa Airlines, your flight to Santa Cruz will be a very pleasant experience. Book your flight today.