Find Copa Airlines flights to Santa Cruz (VVI) from USD445*

Promo Code

Restrictions apply; please see Terms & Conditions.

Fares for flights to Santa Cruz through the Hub of the Americas®,in Panama City

USD

Washington Dulles (IAD)to

Santa Cruz (VVI)
Apr 15, 2026 - Apr 27, 2026
From
USD588
Viewed 1 day ago
Round trip
Economy

New York (JFK)to

Santa Cruz (VVI)
May 14, 2026 - May 31, 2026
From
USD608
Viewed 1 day ago
Round trip
Economy

Los Angeles (LAX)to

Santa Cruz (VVI)
Apr 15, 2026 - May 04, 2026
From
USD668
Viewed 1 day ago
Round trip
Economy

Havana (HAV)to

Santa Cruz (VVI)
Mar 05, 2026 - Mar 30, 2026
From
USD445
Viewed 1 day ago
Round trip
Economy

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Plan your next trip to Santa Cruz with these low fares

USD

Washington Dulles (IAD)to

Santa Cruz (VVI)
Apr 15, 2026 - May 26, 2026

Round trip

Economy

From
USD588
Viewed 1 day ago

New York (JFK)to

Santa Cruz (VVI)
Mar 22, 2026 - Apr 02, 2026

Round trip

Economy

From
USD608
Viewed 13 hours ago

Los Angeles (LAX)to

Santa Cruz (VVI)
Apr 15, 2026 - May 04, 2026

Round trip

Economy

From
USD668
Viewed 1 day ago

Miami (MIA)to

Santa Cruz (VVI)
Mar 30, 2026 - Apr 10, 2026

Round trip

Economy

From
USD501
Viewed 1 day ago

Havana (HAV)to

Santa Cruz (VVI)
Mar 27, 2026 - Apr 04, 2026

Round trip

Economy

From
USD445
Viewed 12 hours ago

Panama (PTY)to

Santa Cruz (VVI)
May 14, 2026 - May 31, 2026

Round trip

Economy

From
USD555
Viewed 21 hours ago

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Fly to Santa Cruz with Copa Air

Santa Cruz receives a third of Bolivia's tourists, attracted by its cultural capital and its entertainment and relaxation activities. Copa Airlines offers flights to Santa Cruz from different parts of the Americas.

What to visit in Santa Cruz?

  • Colonial footprints: the Plaza 24 de Septiembre, located in the city center, is surrounded by buildings dating back to the colonial era, such as the Metropolitan Cathedral, City Hall, and the Cultural Center.
  • Outings in the fresh air: surrounding the city are numerous nature reserves where you can discover the local flora and fauna, participate in outdoor actives, and relax. The most popular are Las Lomas de Arena Regional Park, the Güembé Biocenter, and the Ivaga Guazú Ecological Park.
  • Go shopping: Santa Cruz boasts malls and shops with domestic and imported items, where you can buy a variety of products and gifts.

Getting around Santa Cruz

The simplest way of touring the city is to use some of the 132 urban bus routes. You can also rent a car or take a taxi to reach more remote destinations. Thanks to the excellent service aboard Copa Airlines, your flight to Santa Cruz will be a very pleasant experience. Book your flight today.

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