Find Copa Airlines flights from Medellin (MDE) to Santa Cruz (VVI) from USD478*
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Best prices on Medellin to Santa Cruz flights
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Best airfares from Medellin to Santa Cruz flights
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From | To | Fare Type | Dates | Price |
|---|---|---|---|---|
| Medellin (MDE) | Santa Cruz (VVI) | Round trip / Economy | Oct 15, 2025 - Oct 20, 2025 | From USD478 Viewed 11 hours ago |
| Medellin (MDE) | Santa Cruz (VVI) | Round trip / Economy | Nov 02, 2025 - Nov 08, 2025 | From USD479 Viewed 1 day ago |
| Medellin (MDE) | Santa Cruz (VVI) | Round trip / Economy | Feb 10, 2026 - Mar 10, 2026 | From USD549 Viewed 1 day ago |
| Medellin (MDE) | Santa Cruz (VVI) | Round trip / Economy | Nov 20, 2025 - Dec 21, 2025 | From USD634 Viewed 1 day ago |
*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.
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