What is the best fare to fly from Chicago?

The best fare to fly from Chicago starts at **Flights.FromLowestPrice**. Fly with Copa Airlines.

Find Copa Airlines flights from Chicago (ORD) from USD 717*

1 Passenger

Promo Code

From

Departure

Return

Restrictions apply; please see Terms & Conditions.

Offers on flights from Chicago

From

Budget

USD

Chicago (ORD)to

Cartagena (CTG)

Jun 15, 2026 - Jul 28, 2026

From

USD 315

Viewed 6 hours ago

Round trip

Economy

Chicago (ORD)to

Bogota (BOG)

Sep 16, 2026 - Sep 23, 2026

From

USD 393

Viewed 22 hours ago

Round trip

Economy

Chicago (ORD)to

San Pedro Sula (SAP)

Jul 22, 2026 - Aug 06, 2026

From

USD 395

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Medellin (MDE)

Nov 22, 2026 - Nov 30, 2026

From

USD 415

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Cali (CLO)

Oct 02, 2026 - Oct 12, 2026

From

USD 454

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

San José (SJO)

Jul 02, 2026 - Jul 07, 2026

From

USD 470

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Quito (UIO)

Jun 14, 2026 - Jul 16, 2026

From

USD 474

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Guayaquil (GYE)

Jul 06, 2026 - Aug 15, 2026

From

USD 510

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Lima (LIM)

Jul 03, 2026 - Aug 03, 2026

From

USD 684

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Panama (PTY)

Oct 21, 2026 - Oct 27, 2026

From

USD 717

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Rio de Janeiro (GIG)

Mar 02, 2027 - Mar 08, 2027

From

USD 743

Viewed 20 hours ago

Round trip

Economy

Chicago (ORD)to

Santa Cruz (VVI)

Aug 27, 2026 - Sep 02, 2026

From

USD 760

Viewed 1 day ago

Round trip

Economy

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Best prices on Chicago flights

From

Budget

USD

Chicago (ORD)to

Medellin (MDE)

Jul 01, 2026 - Aug 01, 2026

Round trip

Economy

From

USD 415

Viewed 1 day ago

Chicago (ORD)to

San José (SJO)

Jul 02, 2026 - Jul 07, 2026

Round trip

Economy

From

USD 470

Viewed 1 day ago

Chicago (ORD)to

Quito (UIO)

Sep 09, 2026 - Oct 11, 2026

Round trip

Economy

From

USD 474

Viewed 1 day ago

Chicago (ORD)to

Guayaquil (GYE)

Sep 12, 2026 - Sep 17, 2026

Round trip

Economy

From

USD 510

Viewed 1 day ago

Chicago (ORD)to

Lima (LIM)

Jul 03, 2026 - Aug 03, 2026

Round trip

Economy

From

USD 684

Viewed 1 day ago

Chicago (ORD)to

Panama (PTY)

Oct 21, 2026 - Oct 27, 2026

Round trip

Economy

From

USD 717

Viewed 1 day ago

Flights from Chicago with Copa Airlines

When flying from Chicago, Copa Airlines is the best option. Copa airlines offers you a practical and simple way to enjoy your trip without worrying about the little things. Enter the site and manage your flight details, book hotels, and rent cars.

Leaving Chicago’s International Airport

Chicago O'Hare International Airport (ORD) is located 27 km northwest of the center of the city, where it is easily connected to the 24-hour blue line train. For more convenience, you can take a taxi or hire a private shuttle. We offer free Wi-Fi for the first 20 minutes and charging terminals for electronic devices, so you will always be connected. You can also entertain yourself while waiting for your flight by visiting the variety of shops, restaurants, and art exhibitions.

Flying from Chicago with Copa Airlines

Book your flight from Chicago with Copa Airlines and connect to a growing number of destinations across the continent, enjoying a comfortable, timely and safe journey.