What is the best fare to fly from Chicago?

The best fare to fly from Chicago starts at **Flights.FromLowestPrice**. Fly with Copa Airlines.

Find Copa Airlines flights from Chicago (ORD) from USD319*

1 Passenger

Promo Code

From

Departure

Return

Restrictions apply; please see Terms & Conditions.

Offers on flights from Chicago

From

Budget

USD

Chicago (ORD)to

Bogota (BOG)

Apr 19, 2026 - Apr 28, 2026

From

USD319

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Cartagena (CTG)

Apr 20, 2026 - Apr 23, 2026

From

USD333

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Cali (CLO)

Apr 16, 2026 - Apr 29, 2026

From

USD375

Viewed 13 hours ago

Round trip

Economy

Chicago (ORD)to

Medellin (MDE)

Apr 15, 2026 - May 09, 2026

From

USD393

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Quito (UIO)

Apr 22, 2026 - May 07, 2026

From

USD469

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

San José (SJO)

Jul 18, 2026 - Jul 25, 2026

From

USD470

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Guayaquil (GYE)

Jul 11, 2026 - Aug 18, 2026

From

USD489

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Panama (PTY)

Jul 01, 2026 - Jul 09, 2026

From

USD667

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Lima (LIM)

Apr 19, 2026 - May 23, 2026

From

USD678

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Rio de Janeiro (GIG)

Aug 10, 2026 - Aug 23, 2026

From

USD702

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Sao Paulo (GRU)

May 01, 2026 - May 05, 2026

From

USD748

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Buenos Aires (EZE)

Apr 13, 2026 - Apr 22, 2026

From

USD895

Viewed 1 day ago

Round trip

Economy

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Best prices on Chicago flights

From

Budget

USD

Chicago (ORD)to

Cali (CLO)

May 02, 2026 - May 15, 2026

Round trip

Economy

From

USD391

Viewed 11 hours ago

Chicago (ORD)to

Medellin (MDE)

May 02, 2026 - May 05, 2026

Round trip

Economy

From

USD393

Viewed 10 hours ago

Chicago (ORD)to

Quito (UIO)

May 09, 2026 - May 17, 2026

Round trip

Economy

From

USD469

Viewed 9 hours ago

Chicago (ORD)to

Guayaquil (GYE)

Jul 11, 2026 - Aug 18, 2026

Round trip

Economy

From

USD489

Viewed 1 day ago

Chicago (ORD)to

Panama (PTY)

Jul 18, 2026 - Aug 08, 2026

Round trip

Economy

From

USD667

Viewed 1 day ago

Chicago (ORD)to

Lima (LIM)

Jul 06, 2026 - Jul 22, 2026

Round trip

Economy

From

USD744

Viewed 1 day ago

Flights from Chicago with Copa Airlines

When flying from Chicago, Copa Airlines is the best option. Copa airlines offers you a practical and simple way to enjoy your trip without worrying about the little things. Enter the site and manage your flight details, book hotels, and rent cars.

Leaving Chicago’s International Airport

Chicago O'Hare International Airport (ORD) is located 27 km northwest of the center of the city, where it is easily connected to the 24-hour blue line train. For more convenience, you can take a taxi or hire a private shuttle. We offer free Wi-Fi for the first 20 minutes and charging terminals for electronic devices, so you will always be connected. You can also entertain yourself while waiting for your flight by visiting the variety of shops, restaurants, and art exhibitions.

Flying from Chicago with Copa Airlines

Book your flight from Chicago with Copa Airlines and connect to a growing number of destinations across the continent, enjoying a comfortable, timely and safe journey.