Find Copa Airlines flights from Medellin (MDE) from USD299*
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Restrictions apply; please see Terms & Conditions.
Offers on flights from Medellin
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USD
Medellin (MDE)to
Miami (MIA)May 28, 2026 - May 30, 2026
From
USD299
Viewed 1 day ago
Round trip
Economy
Medellin (MDE)to
San José (SJO)Apr 25, 2026 - May 02, 2026
From
USD309
Viewed 1 day ago
Round trip
Economy
Medellin (MDE)to
Orlando (MCO)Apr 07, 2026 - Apr 14, 2026
From
USD335
Viewed 1 day ago
Round trip
Economy
Medellin (MDE)to
Guatemala (GUA)Apr 19, 2026 - Apr 23, 2026
From
USD339
Viewed 1 day ago
Round trip
Economy
Medellin (MDE)to
Panama (PTY)May 27, 2026 - May 31, 2026
From
USD359
Viewed 1 day ago
Round trip
Economy
Medellin (MDE)to
Mexico City (MEX)Apr 02, 2026 - Apr 09, 2026
From
USD360
Viewed 1 day ago
Round trip
Economy
Medellin (MDE)to
Cancun (CUN)Apr 23, 2026 - Apr 27, 2026
From
USD402
Viewed 22 hours ago
Round trip
Economy
Medellin (MDE)to
New York (JFK)Apr 23, 2026 - Apr 28, 2026
From
USD419
Viewed 1 day ago
Round trip
Economy
Medellin (MDE)to
Sao Paulo (GRU)Apr 05, 2026 - Apr 08, 2026
From
USD448
Viewed 1 day ago
Round trip
Economy
Medellin (MDE)to
Boston (BOS)May 08, 2026 - Jun 03, 2026
From
USD452
Viewed 1 day ago
Round trip
Economy
Medellin (MDE)to
Los Angeles (LAX)Apr 22, 2026 - May 12, 2026
From
USD465
Viewed 1 day ago
Round trip
Economy
Medellin (MDE)to
Rio de Janeiro (GIG)Oct 20, 2026 - Oct 25, 2026
From
USD513
Viewed 16 hours ago
Round trip
Economy
*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.
Best prices on Medellin flights
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flight_land
USD
Medellin (MDE)to
Orlando (MCO)
May 06, 2026 - May 09, 2026
Round trip
Economy
From
USD335
Viewed 1 day ago
Medellin (MDE)to
Panama (PTY)
May 30, 2026 - Aug 29, 2026
Round trip
Economy
From
USD359
Viewed 1 day ago
Medellin (MDE)to
Cancun (CUN)
May 11, 2026 - May 15, 2026
Round trip
Economy
From
USD402
Viewed 11 hours ago
Medellin (MDE)to
New York (JFK)
May 22, 2026 - May 31, 2026
Round trip
Economy
From
USD441
Viewed 16 hours ago
Medellin (MDE)to
Boston (BOS)
May 16, 2026 - May 24, 2026
Round trip
Economy
From
USD452
Viewed 13 hours ago
Medellin (MDE)to
Rio de Janeiro (GIG)
Sep 19, 2026 - Sep 26, 2026
Round trip
Economy
From
USD513
Viewed 1 day ago
*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.
Flights from Medellin with Copa Airlines
Depart on a flight from Medellin with Copa Airlines and take advantage of the extensive network of destinations we offer, as well as complimentary drinks and the loyalty program of ConnectMiles, ideal for frequent travelers.
The José MarÃa Córdova International Airport
Depart from Medellin at the José MarÃa Córdova International Airport (MDE), which is almost an hour away from the city, so take your precautions when you take your flight. This airport operates 24 hours a day and has three restaurants and a commercial area with banking and bureau de change services. Arrive at the airport by taxi, one of the public service buses leaving the San Diego Mall or a rental car.
Your flight from Medellin with Copa Airlines
We offer more than 70 destinations throughout the continent through the Hub of the Americas in Panama City with daily flights from Medellin.
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