What is the best fare to fly from Panama?

The best fare to fly from Panama starts at **Flights.FromLowestPrice**. Fly with Copa Airlines.

Find Copa Airlines flights from Panama (PTY) from USD85*

1 Passenger

Promo Code

From

Departure

Return

Restrictions apply; please see Terms & Conditions.

Offers on flights from Panama

From

Budget

USD

Panama (PTY)to

David (DAV)

Apr 10, 2026 - Apr 21, 2026

From

USD85

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

Bogota (BOG)

Apr 17, 2026 - Apr 22, 2026

From

USD206

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

San José (SJO)

May 23, 2026 - May 31, 2026

From

USD273

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

Miami (MIA)

Apr 22, 2026 - Apr 27, 2026

From

USD292

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

Mexico City (MEX)

May 15, 2026 - May 26, 2026

From

USD304

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

Medellin (MDE)

May 11, 2026 - May 14, 2026

From

USD332

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

Cancun (CUN)

Jun 02, 2026 - Jun 08, 2026

From

USD333

Viewed 16 hours ago

Round trip

Economy

Panama (PTY)to

Guatemala (GUA)

Jun 17, 2026 - Jun 24, 2026

From

USD349

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

Orlando (MCO)

Apr 23, 2026 - May 12, 2026

From

USD404

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

Lima (LIM)

Apr 15, 2026 - Apr 18, 2026

From

USD461

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

Caracas (CCS)

Jun 11, 2026 - Jun 14, 2026

From

USD514

Viewed 16 hours ago

Round trip

Economy

Panama (PTY)to

New York (JFK)

Jul 15, 2026 - Jul 19, 2026

From

USD632

Viewed 1 day ago

Round trip

Economy

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Best prices on Panama flights

From

Budget

USD

Panama (PTY)to

David (DAV)

May 16, 2026 - May 31, 2026

Round trip

Economy

From

USD85

Viewed 1 day ago

Panama (PTY)to

Bogota (BOG)

May 12, 2026 - May 12, 2026

Round trip

Economy

From

USD244

Viewed 15 hours ago

Panama (PTY)to

Miami (MIA)

May 15, 2026 - May 23, 2026

Round trip

Economy

From

USD292

Viewed 1 day ago

Panama (PTY)to

Medellin (MDE)

May 11, 2026 - May 14, 2026

Round trip

Economy

From

USD332

Viewed 1 day ago

Panama (PTY)to

Orlando (MCO)

May 10, 2026 - May 24, 2026

Round trip

Economy

From

USD404

Viewed 1 day ago

Panama (PTY)to

New York (JFK)

Jul 29, 2026 - Aug 09, 2026

Round trip

Economy

From

USD632

Viewed 1 day ago

Flights from Panama with Copa Airlines

Whether you choose to depart from Enrique Malek International Airport (DAV), 6.5 kilometers from the city of David and the closest to the beaches of Bocas del Toro, or from Tocumen International Airport (PTY), 24 kilometers from the Panamanian capital, you can take advantage of dining options and tax-free shopping that both airports offer passengers awaiting their flights. Arrive by shuttle, taxi, or a rental car and get ready to start your t.

Your flight from Panama City with Copa Airlines

Copa Airlines offers you direct flights between both airports in Panama, as well as access to its network of international destinations throughout the Americas from the Tocumen International Airport (PTY), the Hub of the Americas.