What is the best fare to fly from Santa Cruz?

The best fare to fly from Santa Cruz starts at **Flights.FromLowestPrice**. Fly with Copa Airlines.

Find Copa Airlines flights from Santa Cruz (VVI) from USD 783*

1 Passenger

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Departure

Return

Restrictions apply; please see Terms & Conditions.

Round-trip flights from Santa Cruz

From

Budget

USD

Santa Cruz (VVI)to

Miami (MIA)

Nov 03, 2026 - Nov 05, 2026

From

USD 660

Viewed 1 day ago

Round trip

Economy

Santa Cruz (VVI)to

Havana (HAV)

Nov 24, 2026 - Dec 28, 2026

From

USD 682

Viewed 17 hours ago

Round trip

Economy

Santa Cruz (VVI)to

Caracas (CCS)

Feb 02, 2027 - Feb 22, 2027

From

USD 717

Viewed 3 hours ago

Round trip

Economy

Santa Cruz (VVI)to

Washington Dulles (IAD)

Nov 11, 2026 - Nov 16, 2026

From

USD 764

Viewed 22 hours ago

Round trip

Economy

Santa Cruz (VVI)to

Panama (PTY)

Nov 24, 2026 - Nov 30, 2026

From

USD 783

Viewed 1 day ago

Round trip

Economy

Santa Cruz (VVI)to

Punta Cana (PUJ)

Feb 06, 2027 - Feb 13, 2027

From

USD 792

Viewed 11 hours ago

Round trip

Economy

Santa Cruz (VVI)to

Cancun (CUN)

Apr 22, 2027 - Apr 29, 2027

From

USD 796

Viewed 1 day ago

Round trip

Economy

Santa Cruz (VVI)to

Los Angeles (LAX)

Nov 23, 2026 - Dec 04, 2026

From

USD 846

Viewed 1 day ago

Round trip

Economy

Santa Cruz (VVI)to

Mexico City (MEX)

Nov 14, 2026 - Nov 21, 2026

From

USD 870

Viewed 1 day ago

Round trip

Economy

Santa Cruz (VVI)to

Chicago (ORD)

Nov 08, 2026 - Nov 20, 2026

From

USD 893

Viewed 1 day ago

Round trip

Economy

Santa Cruz (VVI)to

New York (JFK)

Apr 30, 2027 - May 13, 2027

From

USD 915

Viewed 1 day ago

Round trip

Economy

Santa Cruz (VVI)to

Las Vegas (LAS)

Nov 19, 2026 - Dec 10, 2026

From

USD 1,166

Viewed 1 day ago

Round trip

Economy

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Round-trip fares from Santa Cruz

From

Budget

USD

Santa Cruz (VVI)to

Miami (MIA)

Apr 12, 2027 - Apr 25, 2027

Round trip

Economy

From

USD 660

Viewed 22 hours ago

Santa Cruz (VVI)to

Havana (HAV)

Feb 01, 2027 - Feb 26, 2027

Round trip

Economy

From

USD 682

Viewed 14 hours ago

Santa Cruz (VVI)to

Washington Dulles (IAD)

Apr 01, 2027 - May 31, 2027

Round trip

Economy

From

USD 764

Viewed 53 minutes ago

Santa Cruz (VVI)to

Panama (PTY)

Dec 20, 2026 - Dec 23, 2026

Round trip

Economy

From

USD 783

Viewed 1 day ago

Santa Cruz (VVI)to

Cancun (CUN)

Mar 03, 2027 - Mar 11, 2027

Round trip

Economy

From

USD 796

Viewed 17 hours ago

Santa Cruz (VVI)to

Mexico City (MEX)

Dec 02, 2026 - Feb 23, 2027

Round trip

Economy

From

USD 870

Viewed 23 hours ago

Flights from Santa Cruz with Copa Airlines

Through its Hub of the Americas, Copa Airlines offers flights from Santa Cruz to more than 60 destinations in the Americas. In addition, your ability to manage the details of your booking online will allow you to enjoy a first-class experience from the moment your purchase your ticket.

Departing from the international airport of Santa Cruz

Viru Viru International Airport (VVI) is located 13 km north of the city centre. The cheapest way to get there is to take a shuttle from the center of the city. The shuttles operate from 5 AM to 8 PM and have space for luggage. Depending on your flight schedule, it is likely that you will need to take a taxi, which are available 24 hours. The airport has several restaurants and coffee shops so that you can relax before boarding. You can also take advantage of the time to shop at the duty-free store.

Travel from Santa Cruz with Copa Airlines

Copa Airlines has one of the newest fleets in the region and provides numerous options for entertainment, movies and music so that your flight from Santa Cruz will be enjoyable. Book your ticket today!