Find Copa Airlines flights from Dominican Republic from USD257*

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Offers on flights from Dominican Republic

From

Budget

USD

Santo Domingo (SDQ)to

Panama (PTY)

May 02, 2026 - May 04, 2026

From

USD548

Viewed 1 day ago

Round trip

Economy

Santo Domingo (SDQ)to

Santiago de Chile (SCL)

Aug 03, 2026 - Aug 31, 2026

From

USD741

Viewed 1 day ago

Round trip

Economy

Santo Domingo (SDQ)to

Caracas (CCS)

Mar 12, 2026 - Mar 18, 2026

From

USD571

Viewed 1 day ago

Round trip

Economy

Santo Domingo (SDQ)to

Medellin (MDE)

May 28, 2026 - May 31, 2026

From

USD286

Viewed 1 day ago

Round trip

Economy

Santo Domingo (SDQ)to

Lima (LIM)

Jul 09, 2026 - Jul 14, 2026

From

USD347

Viewed 1 day ago

Round trip

Economy

Santo Domingo (SDQ)to

Cartagena (CTG)

Mar 29, 2026 - Apr 03, 2026

From

USD273

Viewed 1 day ago

Round trip

Economy

Santo Domingo (SDQ)to

Bogota (BOG)

Feb 11, 2026 - Feb 12, 2026

From

USD257

Viewed 1 day ago

Round trip

Economy

Santiago de los Caballeros (STI)to

Panama (PTY)

Apr 24, 2026 - May 08, 2026

From

USD407

Viewed 1 day ago

Round trip

Economy

Santo Domingo (SDQ)to

San Salvador (SAL)

May 21, 2026 - May 24, 2026

From

USD612

Viewed 1 day ago

Round trip

Economy

Santo Domingo (SDQ)to

Sao Paulo (GRU)

Mar 10, 2026 - Mar 14, 2026

From

USD730

Viewed 1 day ago

Round trip

Economy

Santo Domingo (SDQ)to

San José (SJO)

Mar 08, 2026 - Mar 10, 2026

From

USD286

Viewed 1 day ago

Round trip

Economy

Santo Domingo (SDQ)to

Mexico City (MEX)

Apr 16, 2026 - May 16, 2026

From

USD388

Viewed 1 day ago

Round trip

Economy

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Lowest fares from Dominican Republic

From

Budget

USD

Santo Domingo (SDQ)to

Santiago de Chile (SCL)

Mar 16, 2026 - Mar 23, 2026

Round trip

Economy

From

USD741

Viewed 18 hours ago

Santo Domingo (SDQ)to

Panama (PTY)

May 02, 2026 - May 04, 2026

Round trip

Economy

From

USD548

Viewed 1 day ago

Santo Domingo (SDQ)to

Medellin (MDE)

Mar 12, 2026 - Mar 17, 2026

Round trip

Economy

From

USD286

Viewed 1 day ago

Santo Domingo (SDQ)to

Caracas (CCS)

Mar 12, 2026 - Mar 18, 2026

Round trip

Economy

From

USD571

Viewed 1 day ago

Santo Domingo (SDQ)to

Cartagena (CTG)

Mar 27, 2026 - Apr 03, 2026

Round trip

Economy

From

USD273

Viewed 1 hour ago

Santo Domingo (SDQ)to

Lima (LIM)

Jul 09, 2026 - Jul 14, 2026

Round trip

Economy

From

USD347

Viewed 1 day ago

Travel from Dominican Republic

Copa Airline offers flights from Dominican Republic that depart from Punta Cana (PUJ), Santiago de Caballeros (STI), and of course, Santo Domingo (SDQ). We can connect you to more than 70 important destinations in the American continent from the Hub of the Americas, with our distinctive punctuality and kindness.

A unique flight experience with Copa Airlines

When you travel from Dominican Republic with us, you’ll obtain a world class service and the siplicity to plan the details of your trips on copa.com. You can reserve, not only your flight, but also your hotel, a car, and even travel insurance, so you don’t have to worry for anything later. Copa Airlines also offers you convenient services in its flights from Dominican Republic like online check-in and the luggage calculator. That way, you’ll have everything prepared beforehand, avoiding waiting unnecessarily.