What is the best fare to fly from Guayaquil?

The best fare to fly from Guayaquil starts at **Flights.FromLowestPrice**. Fly with Copa Airlines.

Find Copa Airlines flights from Guayaquil (GYE) from USD 339*

1 Passenger

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Offers on flights from Guayaquil

From

Budget

USD

Guayaquil (GYE)to

Cartagena (CTG)

Oct 14, 2026 - Oct 16, 2026

From

USD 337

Viewed 23 hours ago

Round trip

Economy

Guayaquil (GYE)to

Panama (PTY)

Nov 02, 2026 - Nov 09, 2026

From

USD 339

Viewed 1 day ago

Round trip

Economy

Guayaquil (GYE)to

Miami (MIA)

Dec 17, 2026 - Jan 12, 2027

From

USD 365

Viewed 1 day ago

Round trip

Economy

Guayaquil (GYE)to

Fort Lauderdale (FLL)

Oct 10, 2026 - Oct 18, 2026

From

USD 365

Viewed 1 day ago

Round trip

Economy

Guayaquil (GYE)to

Tampa (TPA)

Oct 16, 2026 - Oct 25, 2026

From

USD 420

Viewed 17 hours ago

Round trip

Economy

Guayaquil (GYE)to

Orlando (MCO)

Oct 10, 2026 - Oct 17, 2026

From

USD 473

Viewed 1 day ago

Round trip

Economy

Guayaquil (GYE)to

Punta Cana (PUJ)

Mar 02, 2027 - Mar 06, 2027

From

USD 508

Viewed 1 day ago

Round trip

Economy

Guayaquil (GYE)to

Chicago (ORD)

Oct 16, 2026 - Nov 28, 2026

From

USD 593

Viewed 1 day ago

Round trip

Economy

Guayaquil (GYE)to

New York (JFK)

Feb 05, 2027 - Feb 10, 2027

From

USD 629

Viewed 1 day ago

Round trip

Economy

Guayaquil (GYE)to

Sao Paulo (GRU)

Jun 04, 2027 - Jun 10, 2027

From

USD 656

Viewed 1 day ago

Round trip

Economy

Guayaquil (GYE)to

Buenos Aires (EZE)

Mar 07, 2027 - Mar 13, 2027

From

USD 667

Viewed 1 day ago

Round trip

Economy

Guayaquil (GYE)to

Los Angeles (LAX)

Nov 09, 2026 - Nov 12, 2026

From

USD 713

Viewed 1 day ago

Round trip

Economy

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Best prices on Guayaquil flights

From

Budget

USD

Guayaquil (GYE)to

Panama (PTY)

Nov 09, 2026 - Nov 12, 2026

Round trip

Economy

From

USD 339

Viewed 1 day ago

Guayaquil (GYE)to

Miami (MIA)

Dec 17, 2026 - Jan 12, 2027

Round trip

Economy

From

USD 365

Viewed 1 day ago

Guayaquil (GYE)to

Fort Lauderdale (FLL)

Nov 24, 2026 - Dec 03, 2026

Round trip

Economy

From

USD 365

Viewed 13 hours ago

Guayaquil (GYE)to

Orlando (MCO)

Nov 17, 2026 - Nov 25, 2026

Round trip

Economy

From

USD 473

Viewed 21 hours ago

Guayaquil (GYE)to

New York (JFK)

Feb 08, 2027 - Mar 06, 2027

Round trip

Economy

From

USD 629

Viewed 1 day ago

Guayaquil (GYE)to

Sao Paulo (GRU)

Mar 01, 2027 - Mar 07, 2027

Round trip

Economy

From

USD 656

Viewed 1 day ago

Flights from Guayaquil with Copa Airlines

If you want to travel from Guayaquil, book your flight with Copa Airlines to connect with over 70 destinations along America and the Caribbean.

Traveling from the Guayaquil International Airport

The José Joaquín de Olmedo International Airport (GYE) is one of the most renowned in the world. Located 5 kilometers from the center of the city, you can reach it via the Line 2 of the Metrovía. Another option is to take a taxi or a private transport that picks you up from the hotel. Inside the airport you will find banks and currency exchange offices, tax-free craft stores and a variety of cafés and restaurants.

Flying from Guayaquil with Copa Airlines

Copa Airlines offers you an average of four flights from Guayaquil to Panama per day. Book your Guayaquil flights today and remember to visit copa.com to manage your travel details conveniently online.