Find Copa Airlines flights from Guayaquil (GYE) to Santiago de Chile (SCL) from USD385*
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Best prices on Guayaquil to Santiago de Chile flights
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Best airfares from Guayaquil to Santiago de Chile flights
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From | To | Fare Type | Dates | Price |
|---|---|---|---|---|
| Guayaquil (GYE) | Santiago de Chile (SCL) | Round trip / Economy | Mar 24, 2026 - Mar 27, 2026 | From USD385 Viewed 3 hours ago |
| Guayaquil (GYE) | Santiago de Chile (SCL) | Round trip / Economy | Apr 14, 2026 - Apr 23, 2026 | From USD409 Viewed 8 hours ago |
| Guayaquil (GYE) | Santiago de Chile (SCL) | Round trip / Economy | Apr 13, 2026 - Apr 23, 2026 | From USD409 Viewed 8 hours ago |
| Guayaquil (GYE) | Santiago de Chile (SCL) | Round trip / Economy | Apr 17, 2026 - Apr 30, 2026 | From USD433 Viewed 1 hour ago |
| Guayaquil (GYE) | Santiago de Chile (SCL) | Round trip / Economy | Apr 14, 2026 - Apr 22, 2026 | From USD440 Viewed 8 hours ago |
*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.
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