What is the best fare to fly from Chicago?

The best fare to fly from Chicago starts at **Flights.FromLowestPrice**. Fly with Copa Airlines.

Find Copa Airlines flights from Chicago (ORD) from USD 737*

1 Passenger

Promo Code

From

Departure

Return

Restrictions apply; please see Terms & Conditions.

Offers on flights from Chicago

From

Budget

USD

Chicago (ORD)to

Cartagena (CTG)

Sep 29, 2026 - Oct 04, 2026

From

USD 353

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Bogota (BOG)

Oct 19, 2026 - Oct 26, 2026

From

USD 403

Viewed 2 hours ago

Round trip

Economy

Chicago (ORD)to

Medellin (MDE)

Nov 14, 2026 - Nov 25, 2026

From

USD 415

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Cali (CLO)

Oct 05, 2026 - Nov 01, 2026

From

USD 450

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Quito (UIO)

Jan 18, 2027 - Jan 30, 2027

From

USD 479

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

San José (SJO)

Aug 08, 2026 - Aug 11, 2026

From

USD 490

Viewed 16 hours ago

Round trip

Economy

Chicago (ORD)to

San Pedro Sula (SAP)

Nov 22, 2026 - Nov 26, 2026

From

USD 507

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Guayaquil (GYE)

Jan 20, 2027 - Feb 03, 2027

From

USD 510

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Lima (LIM)

Jul 16, 2026 - Jul 25, 2026

From

USD 689

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Panama (PTY)

Oct 28, 2026 - Nov 04, 2026

From

USD 737

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Santa Cruz (VVI)

Oct 10, 2026 - Oct 19, 2026

From

USD 760

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Rio de Janeiro (GIG)

Jul 12, 2026 - Jul 17, 2026

From

USD 763

Viewed 1 day ago

Round trip

Economy

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Best prices on Chicago flights

From

Budget

USD

Chicago (ORD)to

Medellin (MDE)

Nov 14, 2026 - Nov 25, 2026

Round trip

Economy

From

USD 415

Viewed 1 day ago

Chicago (ORD)to

Cali (CLO)

Oct 09, 2026 - Nov 08, 2026

Round trip

Economy

From

USD 450

Viewed 1 day ago

Chicago (ORD)to

Quito (UIO)

Sep 21, 2026 - Sep 29, 2026

Round trip

Economy

From

USD 479

Viewed 1 day ago

Chicago (ORD)to

Guayaquil (GYE)

Jul 17, 2026 - Aug 31, 2026

Round trip

Economy

From

USD 510

Viewed 1 day ago

Chicago (ORD)to

Lima (LIM)

Jul 16, 2026 - Jul 25, 2026

Round trip

Economy

From

USD 689

Viewed 1 day ago

Chicago (ORD)to

Panama (PTY)

Oct 28, 2026 - Nov 04, 2026

Round trip

Economy

From

USD 737

Viewed 1 day ago

Flights from Chicago with Copa Airlines

When flying from Chicago, Copa Airlines is the best option. Copa airlines offers you a practical and simple way to enjoy your trip without worrying about the little things. Enter the site and manage your flight details, book hotels, and rent cars.

Leaving Chicago’s International Airport

Chicago O'Hare International Airport (ORD) is located 27 km northwest of the center of the city, where it is easily connected to the 24-hour blue line train. For more convenience, you can take a taxi or hire a private shuttle. We offer free Wi-Fi for the first 20 minutes and charging terminals for electronic devices, so you will always be connected. You can also entertain yourself while waiting for your flight by visiting the variety of shops, restaurants, and art exhibitions.

Flying from Chicago with Copa Airlines

Book your flight from Chicago with Copa Airlines and connect to a growing number of destinations across the continent, enjoying a comfortable, timely and safe journey.