What is the best fare to fly from Chicago?

The best fare to fly from Chicago starts at **Flights.FromLowestPrice**. Fly with Copa Airlines.

Find Copa Airlines flights from Chicago (ORD) from USD 757*

1 Passenger

Promo Code

From

Departure

Return

Restrictions apply; please see Terms & Conditions.

Offers on flights from Chicago

From

Budget

USD

Chicago (ORD)to

Cartagena (CTG)

Sep 09, 2026 - Sep 20, 2026

From

USD 345

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

San José (SJO)

Oct 01, 2026 - Oct 09, 2026

From

USD 346

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Bogota (BOG)

Oct 20, 2026 - Oct 27, 2026

From

USD 393

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Medellin (MDE)

Sep 09, 2026 - Sep 14, 2026

From

USD 415

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Cali (CLO)

Nov 04, 2026 - Nov 12, 2026

From

USD 450

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Quito (UIO)

Sep 15, 2026 - Oct 15, 2026

From

USD 479

Viewed 23 hours ago

Round trip

Economy

Chicago (ORD)to

Guayaquil (GYE)

Sep 14, 2026 - Sep 21, 2026

From

USD 510

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Lima (LIM)

Sep 17, 2026 - Sep 21, 2026

From

USD 655

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Valencia (VLN)

Sep 07, 2026 - Sep 20, 2026

From

USD 668

Viewed 1 hour ago

Round trip

Economy

Chicago (ORD)to

Panama (PTY)

Feb 07, 2027 - Feb 14, 2027

From

USD 757

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Sao Paulo (GRU)

Sep 03, 2026 - Sep 08, 2026

From

USD 793

Viewed 16 hours ago

Round trip

Economy

Chicago (ORD)to

Asuncion (ASU)

Sep 18, 2026 - Sep 21, 2026

From

USD 861

Viewed 1 day ago

Round trip

Economy

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Best prices on Chicago flights

From

Budget

USD

Chicago (ORD)to

San José (SJO)

Sep 28, 2026 - Oct 03, 2026

Round trip

Economy

From

USD 346

Viewed 1 day ago

Chicago (ORD)to

Medellin (MDE)

Sep 09, 2026 - Sep 15, 2026

Round trip

Economy

From

USD 415

Viewed 1 day ago

Chicago (ORD)to

Quito (UIO)

Oct 01, 2026 - Oct 15, 2026

Round trip

Economy

From

USD 479

Viewed 1 day ago

Chicago (ORD)to

Guayaquil (GYE)

Oct 02, 2026 - Oct 22, 2026

Round trip

Economy

From

USD 510

Viewed 1 day ago

Chicago (ORD)to

Lima (LIM)

Sep 10, 2026 - Sep 26, 2026

Round trip

Economy

From

USD 655

Viewed 1 day ago

Chicago (ORD)to

Panama (PTY)

Dec 01, 2026 - Dec 17, 2026

Round trip

Economy

From

USD 757

Viewed 1 day ago

Flights from Chicago with Copa Airlines

When flying from Chicago, Copa Airlines is the best option. Copa airlines offers you a practical and simple way to enjoy your trip without worrying about the little things. Enter the site and manage your flight details, book hotels, and rent cars.

Leaving Chicago’s International Airport

Chicago O'Hare International Airport (ORD) is located 27 km northwest of the center of the city, where it is easily connected to the 24-hour blue line train. For more convenience, you can take a taxi or hire a private shuttle. We offer free Wi-Fi for the first 20 minutes and charging terminals for electronic devices, so you will always be connected. You can also entertain yourself while waiting for your flight by visiting the variety of shops, restaurants, and art exhibitions.

Flying from Chicago with Copa Airlines

Book your flight from Chicago with Copa Airlines and connect to a growing number of destinations across the continent, enjoying a comfortable, timely and safe journey.