What is the best fare to fly from Chicago?

The best fare to fly from Chicago starts at **Flights.FromLowestPrice**. Fly with Copa Airlines.

Find Copa Airlines flights from Chicago (ORD) from USD 777*

1 Passenger

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From

Departure

Return

Restrictions apply; please see Terms & Conditions.

Round-trip flights from Chicago

From

Budget

USD

Chicago (ORD)to

Cartagena (CTG)

Feb 13, 2027 - Feb 16, 2027

From

USD 446

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Cali (CLO)

Jan 18, 2027 - Jan 28, 2027

From

USD 469

Viewed 2 hours ago

Round trip

Economy

Chicago (ORD)to

Bogota (BOG)

Nov 17, 2026 - Nov 19, 2026

From

USD 486

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Medellin (MDE)

Nov 12, 2026 - Nov 16, 2026

From

USD 492

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Guayaquil (GYE)

Nov 23, 2026 - Nov 30, 2026

From

USD 531

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Quito (UIO)

Jan 31, 2027 - Feb 10, 2027

From

USD 557

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Rio de Janeiro (GIG)

Nov 19, 2026 - Nov 27, 2026

From

USD 629

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Santa Cruz (VVI)

Nov 16, 2026 - Dec 02, 2026

From

USD 648

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Panama (PTY)

Feb 09, 2027 - Feb 16, 2027

From

USD 777

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Sao Paulo (GRU)

Nov 14, 2026 - Nov 17, 2026

From

USD 812

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Lima (LIM)

May 17, 2027 - May 23, 2027

From

USD 816

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Caracas (CCS)

Mar 29, 2027 - Mar 30, 2027

From

USD 995

Viewed 1 day ago

Round trip

Economy

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Round-trip fares from Chicago

From

Budget

USD

Chicago (ORD)to

Bogota (BOG)

Dec 30, 2026 - Jan 25, 2027

Round trip

Economy

From

USD 487

Viewed 1 day ago

Chicago (ORD)to

Guayaquil (GYE)

Feb 23, 2027 - Mar 02, 2027

Round trip

Economy

From

USD 531

Viewed 1 day ago

Chicago (ORD)to

Medellin (MDE)

Feb 23, 2027 - Mar 01, 2027

Round trip

Economy

From

USD 536

Viewed 7 hours ago

Chicago (ORD)to

Quito (UIO)

Apr 02, 2027 - Apr 17, 2027

Round trip

Economy

From

USD 557

Viewed 1 day ago

Chicago (ORD)to

Panama (PTY)

Feb 09, 2027 - Feb 16, 2027

Round trip

Economy

From

USD 777

Viewed 1 day ago

Chicago (ORD)to

Lima (LIM)

Feb 11, 2027 - Mar 02, 2027

Round trip

Economy

From

USD 816

Viewed 1 day ago

Flights from Chicago with Copa Airlines

When flying from Chicago, Copa Airlines is the best option. Copa airlines offers you a practical and simple way to enjoy your trip without worrying about the little things. Enter the site and manage your flight details, book hotels, and rent cars.

Leaving Chicago’s International Airport

Chicago O'Hare International Airport (ORD) is located 27 km northwest of the center of the city, where it is easily connected to the 24-hour blue line train. For more convenience, you can take a taxi or hire a private shuttle. We offer free Wi-Fi for the first 20 minutes and charging terminals for electronic devices, so you will always be connected. You can also entertain yourself while waiting for your flight by visiting the variety of shops, restaurants, and art exhibitions.

Flying from Chicago with Copa Airlines

Book your flight from Chicago with Copa Airlines and connect to a growing number of destinations across the continent, enjoying a comfortable, timely and safe journey.