Find Copa Airlines flights from Mexico from USD 370*

1 Passenger

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Departure

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Restrictions apply; please see Terms & Conditions.

Offers on flights from Mexico

From

Budget

USD

Mexico City (MEX)to

Panama (PTY)

Jan 01, 2027 - Jan 17, 2027

From

USD 370

Viewed 1 day ago

Round trip

Economy

Mexico City (MEX)to

Cali (CLO)

Jan 01, 2027 - Jan 23, 2027

From

USD 385

Viewed 1 day ago

Round trip

Economy

Guadalajara (GDL)to

Bogota (BOG)

Oct 22, 2026 - Oct 29, 2026

From

USD 398

Viewed 16 hours ago

Round trip

Economy

Mexico City (MEX)to

Lima (LIM)

Oct 21, 2026 - Nov 04, 2026

From

USD 426

Viewed 1 hour ago

Round trip

Economy

Mexico City (MEX)to

Medellin (MDE)

Oct 19, 2026 - Oct 22, 2026

From

USD 436

Viewed 22 hours ago

Round trip

Economy

Monterrey (MTY)to

Panama (PTY)

Nov 26, 2026 - Nov 29, 2026

From

USD 449

Viewed 1 day ago

Round trip

Economy

Mexico City (MEX)to

Bogota (BOG)

Oct 18, 2026 - Nov 09, 2026

From

USD 467

Viewed 1 day ago

Round trip

Economy

Guadalajara (GDL)to

Panama (PTY)

Jan 25, 2027 - Jan 29, 2027

From

USD 509

Viewed 1 day ago

Round trip

Economy

Mexico City (MEX)to

Caracas (CCS)

Oct 31, 2026 - Nov 11, 2026

From

USD 643

Viewed 1 day ago

Round trip

Economy

Mexico City (MEX)to

Rio de Janeiro (GIG)

Oct 22, 2026 - Nov 04, 2026

From

USD 650

Viewed 18 hours ago

Round trip

Economy

Mexico City (MEX)to

Buenos Aires (EZE)

Oct 22, 2026 - Nov 18, 2026

From

USD 668

Viewed 1 day ago

Round trip

Economy

Monterrey (MTY)to

Buenos Aires (EZE)

Nov 10, 2026 - Nov 17, 2026

From

USD 770

Viewed 1 day ago

Round trip

Economy

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Lowest fares from Mexico

From

Budget

USD

Mexico City (MEX)to

Panama (PTY)

Jan 01, 2027 - Jan 17, 2027

Round trip

Economy

From

USD 370

Viewed 1 day ago

Mexico City (MEX)to

Medellin (MDE)

Jan 01, 2027 - Jan 15, 2027

Round trip

Economy

From

USD 462

Viewed 20 hours ago

Mexico City (MEX)to

Lima (LIM)

Mar 22, 2027 - Mar 29, 2027

Round trip

Economy

From

USD 465

Viewed 1 day ago

Mexico City (MEX)to

Caracas (CCS)

Nov 21, 2026 - Nov 30, 2026

Round trip

Economy

From

USD 643

Viewed 1 day ago

Mexico City (MEX)to

Rio de Janeiro (GIG)

Mar 10, 2027 - Mar 18, 2027

Round trip

Economy

From

USD 674

Viewed 1 day ago

Mexico City (MEX)to

Buenos Aires (EZE)

Nov 30, 2026 - Dec 06, 2026

Round trip

Economy

From

USD 803

Viewed 1 day ago

Travel from Mexico

Traveling from Mexico

From Mexico, you can go anywhere on the continent when you travel through the Hub of the Americas® in Panama with Copa Airlines. Whether you’re traveling from Cancun, Mexico City, Guadalajara, Monterrey, or Puerto Vallarta, Copa Airlines connects you to a growing number of destinations in more than 30 countries across the Americas.

Book your travel at copa.com for a worry-free experience. You’ll be able to manage all your travel details in one place. Purchase your ticket, rent a car, buy travel insurance, or arrange ground transportation. Have you heard about our frequent flyer program yet? To earn valuable miles for every trip, join ConnectMiles free of charge and learn about all the benefits it offers.