What is the best fare to fly from Panama?

The best fare to fly from Panama starts at **Flights.FromLowestPrice**. Fly with Copa Airlines.

Find Copa Airlines flights from Panama (PTY) from USD85*

1 Passenger

Promo Code

From

Departure

Return

Restrictions apply; please see Terms & Conditions.

Offers on flights from Panama

From

Budget

USD

Panama (PTY)to

David (DAV)

Mar 21, 2026 - Apr 12, 2026

From

USD85

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

Bogota (BOG)

Apr 01, 2026 - Apr 04, 2026

From

USD206

Viewed 9 minutes ago

Round trip

Economy

Panama (PTY)to

Medellin (MDE)

May 04, 2026 - May 18, 2026

From

USD255

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

San José (SJO)

May 12, 2026 - May 17, 2026

From

USD273

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

Miami (MIA)

Apr 07, 2026 - May 12, 2026

From

USD292

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

Guatemala (GUA)

Nov 06, 2026 - Nov 14, 2026

From

USD321

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

Mexico City (MEX)

Apr 06, 2026 - May 10, 2026

From

USD326

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

Orlando (MCO)

Apr 02, 2026 - Apr 14, 2026

From

USD404

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

Managua (MGA)

May 30, 2026 - Jun 02, 2026

From

USD410

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

Lima (LIM)

May 11, 2026 - Jun 07, 2026

From

USD446

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

Caracas (CCS)

Mar 18, 2026 - Mar 24, 2026

From

USD515

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

New York (JFK)

Nov 03, 2026 - Nov 08, 2026

From

USD589

Viewed 1 day ago

Round trip

Economy

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Best prices on Panama flights

From

Budget

USD

Panama (PTY)to

David (DAV)

Apr 21, 2026 - Apr 23, 2026

Round trip

Economy

From

USD85

Viewed 1 day ago

Panama (PTY)to

Bogota (BOG)

Apr 30, 2026 - May 06, 2026

Round trip

Economy

From

USD206

Viewed 56 minutes ago

Panama (PTY)to

Medellin (MDE)

May 16, 2026 - May 23, 2026

Round trip

Economy

From

USD255

Viewed 1 day ago

Panama (PTY)to

Miami (MIA)

Apr 17, 2026 - Apr 24, 2026

Round trip

Economy

From

USD292

Viewed 1 day ago

Panama (PTY)to

Orlando (MCO)

Apr 29, 2026 - May 05, 2026

Round trip

Economy

From

USD404

Viewed 1 day ago

Panama (PTY)to

New York (JFK)

May 28, 2026 - Jun 01, 2026

Round trip

Economy

From

USD589

Viewed 1 day ago

Flights from Panama with Copa Airlines

Whether you choose to depart from Enrique Malek International Airport (DAV), 6.5 kilometers from the city of David and the closest to the beaches of Bocas del Toro, or from Tocumen International Airport (PTY), 24 kilometers from the Panamanian capital, you can take advantage of dining options and tax-free shopping that both airports offer passengers awaiting their flights. Arrive by shuttle, taxi, or a rental car and get ready to start your t.

Your flight from Panama City with Copa Airlines

Copa Airlines offers you direct flights between both airports in Panama, as well as access to its network of international destinations throughout the Americas from the Tocumen International Airport (PTY), the Hub of the Americas.