What is the best fare to fly from Panama?

The best fare to fly from Panama starts at **Flights.FromLowestPrice**. Fly with Copa Airlines.

Find Copa Airlines flights from Panama (PTY) from #%#Flights.FromLowestPrice#%#

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Restrictions apply; please see Terms & Conditions.

Round-trip flights from Panama

From

Budget

USD

Panama (PTY)to

David (DAV)

Nov 27, 2026 - Nov 28, 2026

From

USD 91

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

Managua (MGA)

Nov 27, 2026 - Dec 11, 2026

From

USD 251

Viewed 15 hours ago

Round trip

Economy

Panama (PTY)to

San José (SJO)

Nov 14, 2026 - Nov 18, 2026

From

USD 267

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

Cartagena (CTG)

Jan 16, 2027 - Jan 17, 2027

From

USD 271

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

Medellin (MDE)

Dec 10, 2026 - Dec 11, 2026

From

USD 300

Viewed 17 hours ago

Round trip

Economy

Panama (PTY)to

Bogota (BOG)

Nov 04, 2026 - Nov 04, 2026

From

USD 313

Viewed 14 hours ago

Round trip

Economy

Panama (PTY)to

Mexico City (MEX)

Dec 25, 2026 - Jan 06, 2027

From

USD 375

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

Miami (MIA)

Dec 04, 2026 - Dec 12, 2026

From

USD 445

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

Lima (LIM)

Jan 17, 2027 - Jan 23, 2027

From

USD 518

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

Caracas (CCS)

Nov 09, 2026 - Nov 30, 2026

From

USD 610

Viewed 1 day ago

Round trip

Economy

Panama (PTY)to

Orlando (MCO)

Feb 04, 2027 - Feb 10, 2027

From

USD 618

Viewed 7 hours ago

Round trip

Economy

Panama (PTY)to

New York (JFK)

Oct 31, 2026 - Dec 08, 2026

From

USD 670

Viewed 1 day ago

Round trip

Economy

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Round-trip fares from Panama

From

Budget

USD

Panama (PTY)to

David (DAV)

Dec 02, 2026 - Dec 08, 2026

Round trip

Economy

From

USD 91

Viewed 1 day ago

Panama (PTY)to

Medellin (MDE)

Jan 25, 2027 - Jan 25, 2027

Round trip

Economy

From

USD 300

Viewed 19 hours ago

Panama (PTY)to

Bogota (BOG)

Dec 10, 2026 - Dec 10, 2026

Round trip

Economy

From

USD 313

Viewed 1 day ago

Panama (PTY)to

Mexico City (MEX)

Dec 25, 2026 - Jan 06, 2027

Round trip

Economy

From

USD 375

Viewed 1 day ago

Panama (PTY)to

Miami (MIA)

Dec 10, 2026 - Dec 12, 2026

Round trip

Economy

From

USD 445

Viewed 1 day ago

Panama (PTY)to

Orlando (MCO)

Feb 04, 2027 - Feb 10, 2027

Round trip

Economy

From

USD 618

Viewed 7 hours ago

Flights from Panama with Copa Airlines

Whether you choose to depart from Enrique Malek International Airport (DAV), 6.5 kilometers from the city of David and the closest to the beaches of Bocas del Toro, or from Tocumen International Airport (PTY), 24 kilometers from the Panamanian capital, you can take advantage of dining options and tax-free shopping that both airports offer passengers awaiting their flights. Arrive by shuttle, taxi, or a rental car and get ready to start your t.

Your flight from Panama City with Copa Airlines

Copa Airlines offers you direct flights between both airports in Panama, as well as access to its network of international destinations throughout the Americas from the Tocumen International Airport (PTY), the Hub of the Americas.