Find Copa Airlines flights from Panama (PTY) to Medellin (MDE) from USD 276*

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Restrictions apply; please see Terms & Conditions.

Best prices on Panama to Medellin flights

cmp-daily-histogram-bars-legend-min-price-aria-label USD 276
cmp-daily-histogram-bars-legend-max-price-aria-label USD 647
Displaying fares for September-2026
  • PTY–MDE, Sep 14, 2026 – Sep 30, 2026: From USD 276
    14

    Mon

    SEP

  • PTY–MDE, Sep 15, 2026 – Oct 14, 2026: From USD 276
    15

    Tue

  • PTY–MDE, Sep 16, 2026 – Sep 17, 2026: From USD 276
    16

    Wed

  • PTY–MDE, Sep 17, 2026 – Sep 22, 2026: From USD 276
    17

    Thu

  • PTY–MDE, Sep 18, 2026 – Sep 23, 2026: From USD 276
    18

    Fri

  • PTY–MDE, Sep 19, 2026 – Sep 22, 2026: From USD 276
    19

    Sat

  • PTY–MDE, Sep 20, 2026 – Sep 26, 2026: From USD 276
    20

    Sun

  • PTY–MDE, Sep 21, 2026 – Sep 23, 2026: From USD 276
    21

    Mon

  • PTY–MDE, Sep 22, 2026 – Sep 26, 2026: From USD 276
    22

    Tue

  • PTY–MDE, Sep 23, 2026 – Sep 23, 2026: From USD 276
    23

    Wed

  • PTY–MDE, Sep 24, 2026 – Sep 29, 2026: From USD 342
    24

    Thu

  • PTY–MDE, Sep 25, 2026 – Sep 26, 2026: From USD 315
    25

    Fri

  • PTY–MDE, Sep 26, 2026 – Sep 26, 2026: From USD 276
    26

    Sat

  • PTY–MDE, Sep 27, 2026 – Oct 04, 2026: From USD 325
    27

    Sun

  • PTY–MDE, Sep 28, 2026 – Sep 30, 2026: From USD 276
    28

    Mon

  • PTY–MDE, Sep 29, 2026 – Oct 01, 2026: From USD 276
    29

    Tue

  • PTY–MDE, Sep 30, 2026 – Oct 07, 2026: From USD 276
    30

    Wed

  • PTY–MDE, Oct 01, 2026 – Oct 07, 2026: From USD 325
    01

    Thu

    OCT

  • PTY–MDE, Oct 02, 2026 – Oct 06, 2026: From USD 315
    02

    Fri

  • PTY–MDE, Oct 03, 2026 – Oct 14, 2026: From USD 276
    03

    Sat

  • PTY–MDE, Oct 04, 2026 – Oct 07, 2026: From USD 276
    04

    Sun

  • PTY–MDE, Oct 05, 2026 – Oct 14, 2026: From USD 276
    05

    Mon

  • PTY–MDE, Oct 06, 2026 – Oct 31, 2026: From USD 276
    06

    Tue

  • PTY–MDE, Oct 07, 2026 – Oct 14, 2026: From USD 430
    07

    Wed

  • PTY–MDE, Oct 08, 2026 – Oct 15, 2026: From USD 598
    08

    Thu

  • PTY–MDE, Oct 09, 2026 – Oct 15, 2026: From USD 598
    09

    Fri

  • PTY–MDE, Oct 10, 2026 – Oct 14, 2026: From USD 598
    10

    Sat

  • PTY–MDE, Oct 11, 2026 – Oct 18, 2026: From USD 647
    11

    Sun

  • PTY–MDE, Oct 12, 2026 – Oct 16, 2026: From USD 598
    12

    Mon

  • PTY–MDE, Oct 13, 2026 – Oct 20, 2026: From USD 598
    13

    Tue

  • FromUSD 276-USD 647

    Best airfares from Panama to Medellin flights

    USD
    Best airfares from Panama to Medellin flights
    From
    To
    Fare Type
    Dates
    Price
    Panama (PTY)Medellin (MDE)Round trip
    /
    Economy
    Sep 14, 2026 - Oct 14, 2026

    From

    USD 276

    Viewed 1 day ago

    Panama (PTY)Medellin (MDE)Round trip
    /
    Economy
    Oct 15, 2026 - Oct 17, 2026

    From

    USD 276

    Viewed 1 day ago

    Panama (PTY)Medellin (MDE)Round trip
    /
    Economy
    Oct 19, 2026 - Oct 24, 2026

    From

    USD 276

    Viewed 1 day ago

    Panama (PTY)Medellin (MDE)Round trip
    /
    Economy
    Nov 07, 2026 - Nov 09, 2026

    From

    USD 276

    Viewed 1 day ago

    Panama (PTY)Medellin (MDE)Round trip
    /
    Economy
    Oct 04, 2026 - Oct 10, 2026

    From

    USD 276

    Viewed 1 day ago

    *Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
    *Restrictions apply; please see Terms & Conditions.

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