What is the best fare to fly from Raleigh?

The best fare to fly from Raleigh starts at **Flights.FromLowestPrice**. Fly with Copa Airlines.

Find Copa Airlines flights from Raleigh (RDU) from USD221*

1 Passenger

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From

Departure

Return

Restrictions apply; please see Terms & Conditions.

Offers on flights from Raleigh

From

Budget

USD

Raleigh (RDU)to

Panama (PTY)

Apr 13, 2026 - Apr 17, 2026

From

USD447

Viewed 1 day ago

Round trip

Economy

Raleigh (RDU)to

San Salvador (SAL)

Feb 08, 2026 - Feb 16, 2026

From

USD255

Viewed 18 hours ago

Round trip

Economy

Raleigh (RDU)to

Medellin (MDE)

Feb 23, 2026 - Mar 02, 2026

From

USD271

Viewed 23 hours ago

Round trip

Economy

Raleigh (RDU)to

Bogota (BOG)

Feb 16, 2026 - Apr 15, 2026

From

USD263

Viewed 1 day ago

Round trip

Economy

Raleigh (RDU)to

Guatemala (GUA)

Apr 13, 2026 - Apr 17, 2026

From

USD221

Viewed 1 day ago

Round trip

Economy

Raleigh (RDU)to

Guayaquil (GYE)

May 18, 2026 - Jun 03, 2026

From

USD341

Viewed 1 hour ago

Round trip

Economy

Raleigh (RDU)to

Cartagena (CTG)

Mar 02, 2026 - Mar 09, 2026

From

USD259

Viewed 15 hours ago

Round trip

Economy

Raleigh (RDU)to

Cali (CLO)

Feb 08, 2026 - Feb 15, 2026

From

USD363

Viewed 1 day ago

Round trip

Economy

Raleigh (RDU)to

San José (SJO)

Mar 04, 2026 - Mar 11, 2026

From

USD241

Viewed 1 day ago

Round trip

Economy

Raleigh (RDU)to

Sao Paulo (GRU)

Mar 16, 2026 - Mar 30, 2026

From

USD440

Viewed 15 hours ago

Round trip

Economy

Raleigh (RDU)to

Santa Cruz (VVI)

Feb 25, 2026 - Mar 11, 2026

From

USD580

Viewed 3 hours ago

Round trip

Economy

Raleigh (RDU)to

Lima (LIM)

Mar 25, 2026 - Mar 30, 2026

From

USD459

Viewed 30 minutes ago

Round trip

Economy

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Best prices on Raleigh flights

From

Budget

USD

Raleigh (RDU)to

Panama (PTY)

Apr 13, 2026 - Apr 17, 2026

Round trip

Economy

From

USD447

Viewed 1 day ago

Raleigh (RDU)to

San Salvador (SAL)

Mar 22, 2026 - Apr 19, 2026

Round trip

Economy

From

USD282

Viewed 23 hours ago

Raleigh (RDU)to

Bogota (BOG)

Apr 15, 2026 - Apr 26, 2026

Round trip

Economy

From

USD263

Viewed 1 day ago

Raleigh (RDU)to

Guatemala (GUA)

Apr 13, 2026 - Apr 17, 2026

Round trip

Economy

From

USD221

Viewed 1 day ago

Raleigh (RDU)to

Medellin (MDE)

Mar 20, 2026 - Apr 26, 2026

Round trip

Economy

From

USD287

Viewed 1 hour ago

Raleigh (RDU)to

Lima (LIM)

Mar 25, 2026 - Mar 30, 2026

Round trip

Economy

From

USD459

Viewed 30 minutes ago

Flights from Raleigh with Copa Airlines

TRAVELING FROM RALEIGH-DURHAM

Get ready to take off to new horizons with flights from Raleigh-Durham! At Copa Airlines, we believe that every flight is an opportunity to explore, discover and connect with the world that awaits you. Our mission is to offer you the best way to get you to exciting destinations throughout the continent directly and efficiently through the Hub of the Americas® at Tocumen International Airport, Panama City.

The freedom to explore is in your hands. Make your reservation at copa.com and discover the ease of managing all the details of your itinerary from a single platform. We're here to inspire you to fly high, connect with new cultures and experience unforgettable adventures in Latin America - get ready to unleash your travel spirit with Copa Airlines!

DEPARTING FROM RALEIGH-DURHAM INTERNATIONAL AIRPORT

Located in the northwest area, a short distance from the city center, Raleigh-Durham International Airport (RDU) offers four weekly flights to and from Panama City. This airport provides excellent accessibility thanks to various transportation alternatives, including buses, trains and private services such as cabs or shuttles, which you can easily coordinate from your accommodation. As you enter the airport, you'll find a variety of options to keep you from getting bored, with art exhibits, restaurants and stores sure to keep you busy while you wait for your flight to depart. Get ready for an unparalleled travel experience from Raleigh-Durham with Copa Airlines!