What is the best fare to fly from Santiago de Chile?

The best fare to fly from Santiago de Chile starts at **Flights.FromLowestPrice**. Fly with Copa Airlines.

Find Copa Airlines flights from Santiago de Chile (SCL) from USD 640*

1 Passenger

Promo Code

From

Departure

Return

Restrictions apply; please see Terms & Conditions.

Round-trip flights from Santiago de Chile

From

Budget

USD

Santiago de Chile (SCL)to

San José (SJO)

Nov 17, 2026 - Nov 20, 2026

From

USD 486

Viewed 14 hours ago

Round trip

Economy

Santiago de Chile (SCL)to

Punta Cana (PUJ)

Mar 14, 2027 - Mar 22, 2027

From

USD 488

Viewed 6 hours ago

Round trip

Economy

Santiago de Chile (SCL)to

Maracaibo (MAR)

Nov 05, 2026 - Nov 29, 2026

From

USD 528

Viewed 1 day ago

Round trip

Economy

Santiago de Chile (SCL)to

Santo Domingo (SDQ)

Dec 05, 2026 - Dec 08, 2026

From

USD 574

Viewed 1 day ago

Round trip

Economy

Santiago de Chile (SCL)to

Miami (MIA)

Nov 16, 2026 - Dec 08, 2026

From

USD 583

Viewed 1 day ago

Round trip

Economy

Santiago de Chile (SCL)to

Panama (PTY)

Dec 05, 2026 - Dec 08, 2026

From

USD 640

Viewed 13 hours ago

Round trip

Economy

Santiago de Chile (SCL)to

Havana (HAV)

Nov 23, 2026 - Nov 30, 2026

From

USD 644

Viewed 1 day ago

Round trip

Economy

Santiago de Chile (SCL)to

Valencia (VLN)

Nov 02, 2026 - Nov 27, 2026

From

USD 669

Viewed 14 hours ago

Round trip

Economy

Santiago de Chile (SCL)to

Cancun (CUN)

Mar 07, 2027 - Mar 18, 2027

From

USD 727

Viewed 1 day ago

Round trip

Economy

Santiago de Chile (SCL)to

Barcelona, Venezuela (BLA)

Feb 28, 2027 - Mar 27, 2027

From

USD 729

Viewed 1 day ago

Round trip

Economy

Santiago de Chile (SCL)to

Caracas (CCS)

Nov 11, 2026 - Nov 17, 2026

From

USD 729

Viewed 7 hours ago

Round trip

Economy

Santiago de Chile (SCL)to

Barquisimeto (BRM)

Aug 14, 2027 - Sep 23, 2027

From

USD 815

Viewed 11 hours ago

Round trip

Economy

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Round-trip fares from Santiago de Chile

From

Budget

USD

Santiago de Chile (SCL)to

Punta Cana (PUJ)

Mar 14, 2027 - Mar 22, 2027

Round trip

Economy

From

USD 488

Viewed 6 hours ago

Santiago de Chile (SCL)to

Santo Domingo (SDQ)

Dec 05, 2026 - Dec 08, 2026

Round trip

Economy

From

USD 574

Viewed 1 day ago

Santiago de Chile (SCL)to

Maracaibo (MAR)

Apr 08, 2027 - Apr 17, 2027

Round trip

Economy

From

USD 645

Viewed 15 hours ago

Santiago de Chile (SCL)to

Barcelona, Venezuela (BLA)

Feb 28, 2027 - Mar 27, 2027

Round trip

Economy

From

USD 729

Viewed 1 day ago

Santiago de Chile (SCL)to

Caracas (CCS)

Apr 01, 2027 - Apr 18, 2027

Round trip

Economy

From

USD 765

Viewed 1 day ago

Santiago de Chile (SCL)to

Valencia (VLN)

Apr 14, 2027 - May 02, 2027

Round trip

Economy

From

USD 782

Viewed 22 hours ago

Flights from Santiago de Chile with Copa Airlines

Traveling from Santiago

If you want to travel in comfort while enjoying excellent service and a variety of in-flight entertainment, book your trip from Comodoro Arturo Merino Benitez International Airport (SCL) in Santiago today. You can look forward to world-class service from an airline renowned for its on-time performance. Copa Airlines connects you to a growing network of destinations across the continent through the Hub of the Americas® in Panama.

Traveling out of Comodoro Arturo Merino Benitez International Airport

Comodoro Arturo Merino Benitez International Airport is Chile’s leading airport, and it’s about a 30-minute drive west of downtown Santiago. Two bus companies offer service between the city and the airport, and a variety of other public and private transportation options are also available. At copa.com, you can arrange your transportation to the airport, book your hotel stay, and more. Using our mobile app or website makes it easy to manage all the details of your reservation and check in for your flight from the comfort of your own home.