What is the best fare to fly from Santiago de Chile?

The best fare to fly from Santiago de Chile starts at **Flights.FromLowestPrice**. Fly with Copa Airlines.

Find Copa Airlines flights from Santiago de Chile (SCL) from USD384*

1 Passenger

Promo Code

From

Departure

Return

Restrictions apply; please see Terms & Conditions.

Offers on flights from Santiago de Chile

From

Budget

USD

Santiago de Chile (SCL)to

San José (SJO)

May 06, 2026 - Jun 03, 2026

From

USD384

Viewed 22 hours ago

Round trip

Economy

Santiago de Chile (SCL)to

Cali (CLO)

Mar 27, 2026 - Apr 06, 2026

From

USD401

Viewed 1 day ago

Round trip

Economy

Santiago de Chile (SCL)to

Panama (PTY)

Apr 30, 2026 - May 31, 2026

From

USD515

Viewed 1 day ago

Round trip

Economy

Santiago de Chile (SCL)to

Cucuta (CUC)

Apr 10, 2026 - Apr 27, 2026

From

USD534

Viewed 17 hours ago

Round trip

Economy

Santiago de Chile (SCL)to

Santo Domingo (SDQ)

Mar 21, 2026 - Mar 30, 2026

From

USD581

Viewed 1 day ago

Round trip

Economy

Santiago de Chile (SCL)to

Havana (HAV)

Mar 20, 2026 - Apr 20, 2026

From

USD584

Viewed 1 day ago

Round trip

Economy

Santiago de Chile (SCL)to

Punta Cana (PUJ)

Jun 07, 2026 - Jun 14, 2026

From

USD607

Viewed 1 day ago

Round trip

Economy

Santiago de Chile (SCL)to

Cancun (CUN)

Jul 16, 2026 - Jul 31, 2026

From

USD617

Viewed 19 hours ago

Round trip

Economy

Santiago de Chile (SCL)to

Mexico City (MEX)

Mar 29, 2026 - Apr 07, 2026

From

USD632

Viewed 21 hours ago

Round trip

Economy

Santiago de Chile (SCL)to

Maracaibo (MAR)

Mar 31, 2026 - Apr 22, 2026

From

USD636

Viewed 3 hours ago

Round trip

Economy

Santiago de Chile (SCL)to

Caracas (CCS)

Mar 18, 2026 - Mar 29, 2026

From

USD645

Viewed 13 hours ago

Round trip

Economy

Santiago de Chile (SCL)to

Miami (MIA)

May 15, 2026 - May 27, 2026

From

USD713

Viewed 1 day ago

Round trip

Economy

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Best prices on Santiago de Chile flights

From

Budget

USD

Santiago de Chile (SCL)to

Panama (PTY)

Apr 30, 2026 - May 03, 2026

Round trip

Economy

From

USD515

Viewed 1 day ago

Santiago de Chile (SCL)to

Santo Domingo (SDQ)

Apr 15, 2026 - Apr 22, 2026

Round trip

Economy

From

USD581

Viewed 1 day ago

Santiago de Chile (SCL)to

Havana (HAV)

May 03, 2026 - May 10, 2026

Round trip

Economy

From

USD584

Viewed 1 day ago

Santiago de Chile (SCL)to

Punta Cana (PUJ)

Jun 07, 2026 - Jun 14, 2026

Round trip

Economy

From

USD607

Viewed 1 day ago

Santiago de Chile (SCL)to

Maracaibo (MAR)

Apr 29, 2026 - May 15, 2026

Round trip

Economy

From

USD636

Viewed 5 hours ago

Santiago de Chile (SCL)to

Caracas (CCS)

Apr 18, 2026 - Aug 16, 2026

Round trip

Economy

From

USD768

Viewed 12 minutes ago

Flights from Santiago de Chile with Copa Airlines

Traveling from Santiago

If you want to travel in comfort while enjoying excellent service and a variety of in-flight entertainment, book your trip from Comodoro Arturo Merino Benitez International Airport (SCL) in Santiago today. You can look forward to world-class service from an airline renowned for its on-time performance. Copa Airlines connects you to a growing network of destinations across the continent through the Hub of the Americas® in Panama.

Traveling out of Comodoro Arturo Merino Benitez International Airport

Comodoro Arturo Merino Benitez International Airport is Chile’s leading airport, and it’s about a 30-minute drive west of downtown Santiago. Two bus companies offer service between the city and the airport, and a variety of other public and private transportation options are also available. At copa.com, you can arrange your transportation to the airport, book your hotel stay, and more. Using our mobile app or website makes it easy to manage all the details of your reservation and check in for your flight from the comfort of your own home.