Find Copa Airlines flights from Santiago de Chile (SCL) to Medellin (MDE) from USD375*

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Restrictions apply; please see Terms & Conditions.

Best prices on Santiago de Chile to Medellin flights

Apr 2026
FromUSD390*
Viewed 2 hours ago
Round trip/Economy
May 2026
FromUSD375*
Viewed 4 hours ago
Round trip/Economy
Jun 2026
FromUSD415*
Viewed 1 day ago
Round trip/Economy
USD375
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    • FromUSD375-USD453

    *Restrictions apply; please see Terms & Conditions.

    Best airfares from Santiago de Chile to Medellin flights

    USD
    Best airfares from Santiago de Chile to Medellin flights
    From
    To
    Fare Type
    Dates
    Price
    Santiago de Chile (SCL)Medellin (MDE)Round trip
    /
    Economy    		May 07, 2026 - May 13, 2026

    From

    USD375

    Viewed 4 hours ago

    Santiago de Chile (SCL)Medellin (MDE)Round trip
    /
    Economy    		May 20, 2026 - May 26, 2026

    From

    USD375

    Viewed 3 hours ago

    Santiago de Chile (SCL)Medellin (MDE)Round trip
    /
    Economy    		Apr 22, 2026 - May 09, 2026

    From

    USD390

    Viewed 2 hours ago

    Santiago de Chile (SCL)Medellin (MDE)Round trip
    /
    Economy    		Apr 23, 2026 - May 09, 2026

    From

    USD395

    Viewed 2 hours ago

    Santiago de Chile (SCL)Medellin (MDE)Round trip
    /
    Economy    		May 20, 2026 - Jun 02, 2026

    From

    USD395

    Viewed 2 hours ago

    *Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
    *Restrictions apply; please see Terms & Conditions.

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