Find Copa Airlines flights from Santiago de Chile (SCL) to Guayaquil (GYE) from USD422*
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Best prices on Santiago de Chile to Guayaquil flights
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Best airfares from Santiago de Chile to Guayaquil flights
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From | To | Fare Type | Dates | Price |
|---|---|---|---|---|
| Santiago de Chile (SCL) | Guayaquil (GYE) | Round trip / Economy | Mar 20, 2026 - Apr 15, 2026 | From USD422 Viewed 23 hours ago |
| Santiago de Chile (SCL) | Guayaquil (GYE) | Round trip / Economy | Jun 25, 2026 - Jul 14, 2026 | From USD443 Viewed 9 minutes ago |
| Santiago de Chile (SCL) | Guayaquil (GYE) | Round trip / Economy | Nov 26, 2025 - Dec 01, 2025 | From USD463 Viewed 1 day ago |
| Santiago de Chile (SCL) | Guayaquil (GYE) | Round trip / Economy | Nov 28, 2025 - Dec 04, 2025 | From USD463 Viewed 16 hours ago |
| Santiago de Chile (SCL) | Guayaquil (GYE) | Round trip / Economy | Nov 25, 2025 - Nov 29, 2025 | From USD475 Viewed 1 day ago |
*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.
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