Find Copa Airlines flights from Mexico from MXN4,242*

1 Passenger

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Restrictions apply; please see Terms & Conditions.

Offers on flights from Mexico

From

Budget

MXN

Mexico City (MEX)to

Panama (PTY)

Mar 13, 2026 - Mar 21, 2026

From

MXN5,548

Viewed 1 day ago

Round trip

Economy

Mexico City (MEX)to

Caracas (CCS)

Feb 25, 2026 - Mar 09, 2026

From

MXN11,525

Viewed 1 day ago

Round trip

Economy

Mexico City (MEX)to

Rio de Janeiro (GIG)

Mar 07, 2026 - Mar 14, 2026

From

MXN8,441

Viewed 1 day ago

Round trip

Economy

Mexico City (MEX)to

Lima (LIM)

Feb 03, 2026 - Feb 07, 2026

From

MXN4,758

Viewed 1 day ago

Round trip

Economy

Mexico City (MEX)to

Cartagena (CTG)

Mar 05, 2026 - Mar 08, 2026

From

MXN5,033

Viewed 1 day ago

Round trip

Economy

Mexico City (MEX)to

Sao Paulo (GRU)

Feb 14, 2026 - Feb 28, 2026

From

MXN8,545

Viewed 1 day ago

Round trip

Economy

Cancun (CUN)to

Panama (PTY)

Feb 08, 2026 - Feb 12, 2026

From

MXN4,886

Viewed 1 day ago

Round trip

Economy

Mexico City (MEX)to

Medellin (MDE)

Feb 02, 2026 - Feb 05, 2026

From

MXN5,667

Viewed 1 day ago

Round trip

Economy

Guadalajara (GDL)to

Panama (PTY)

Jan 21, 2026 - Jan 25, 2026

From

MXN7,588

Viewed 1 day ago

Round trip

Economy

Monterrey (MTY)to

Medellin (MDE)

Nov 13, 2026 - Nov 29, 2026

From

MXN4,489

Viewed 1 day ago

Round trip

Economy

Mexico City (MEX)to

Buenos Aires (EZE)

Mar 07, 2026 - Mar 16, 2026

From

MXN11,213

Viewed 1 day ago

Round trip

Economy

Mexico City (MEX)to

Punta Cana (PUJ)

Feb 20, 2026 - Feb 25, 2026

From

MXN6,202

Viewed 1 day ago

Round trip

Economy

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Lowest fares from Mexico

From

Budget

MXN

Mexico City (MEX)to

Panama (PTY)

Mar 13, 2026 - Mar 21, 2026

Round trip

Economy

From

MXN5,548

Viewed 1 day ago

Mexico City (MEX)to

Caracas (CCS)

Feb 25, 2026 - Mar 09, 2026

Round trip

Economy

From

MXN11,525

Viewed 1 day ago

Mexico City (MEX)to

Rio de Janeiro (GIG)

Mar 13, 2026 - Mar 17, 2026

Round trip

Economy

From

MXN8,441

Viewed 1 day ago

Mexico City (MEX)to

Lima (LIM)

Feb 24, 2026 - Mar 03, 2026

Round trip

Economy

From

MXN4,758

Viewed 1 day ago

Mexico City (MEX)to

Cartagena (CTG)

Mar 05, 2026 - Mar 08, 2026

Round trip

Economy

From

MXN5,033

Viewed 1 day ago

Mexico City (MEX)to

Medellin (MDE)

Apr 14, 2026 - Apr 30, 2026

Round trip

Economy

From

MXN5,667

Viewed 1 day ago

Travel from Mexico

Traveling from Mexico

From Mexico, you can go anywhere on the continent when you travel through the Hub of the Americas® in Panama with Copa Airlines. Whether you’re traveling from Cancun, Mexico City, Guadalajara, Monterrey, or Puerto Vallarta, Copa Airlines connects you to a growing number of destinations in more than 30 countries across the Americas.

Book your travel at copa.com for a worry-free experience. You’ll be able to manage all your travel details in one place. Purchase your ticket, rent a car, buy travel insurance, or arrange ground transportation. Have you heard about our frequent flyer program yet? To earn valuable miles for every trip, join ConnectMiles free of charge and learn about all the benefits it offers.