Find Copa Airlines flights from Mexico from MXN4,204*

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Restrictions apply; please see Terms & Conditions.

Offers on flights from Mexico

From

Mexico City (MEX)to

Panama (PTY)

Sep 26, 2025 - Oct 04, 2025

From

MXN5,276

Viewed 7 hours ago

Round trip
/
Economy

Mexico City (MEX)to

Caracas (CCS)

Oct 11, 2025 - Oct 18, 2025

From

MXN12,383

Viewed 14 hours ago

Round trip
/
Economy

Mexico City (MEX)to

Rio de Janeiro (GIG)

Nov 16, 2025 - Nov 24, 2025

From

MXN8,977

Viewed 16 hours ago

Round trip
/
Economy

Mexico City (MEX)to

Medellin (MDE)

Oct 29, 2025 - Nov 07, 2025

From

MXN5,538

Viewed 14 hours ago

Round trip
/
Economy

Mexico City (MEX)to

Bogota (BOG)

Sep 03, 2025 - Sep 06, 2025

From

MXN4,762

Viewed 12 hours ago

Round trip
/
Economy

Mexico City (MEX)to

Cucuta (CUC)

Sep 16, 2025 - Sep 18, 2025

From

MXN7,849

Viewed 1 day ago

Round trip
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Economy

Mexico City (MEX)to

Cartagena (CTG)

Jan 30, 2026 - Feb 28, 2026

From

MXN5,652

Viewed 4 hours ago

Round trip
/
Economy

Mexico City (MEX)to

Sao Paulo (GRU)

Nov 07, 2025 - Nov 16, 2025

From

MXN8,450

Viewed 7 hours ago

Round trip
/
Economy

Mexico City (MEX)to

Lima (LIM)

Oct 02, 2025 - Oct 09, 2025

From

MXN5,628

Viewed 16 hours ago

Round trip
/
Economy

Guadalajara (GDL)to

Bogota (BOG)

Oct 09, 2025 - Oct 15, 2025

From

MXN4,838

Viewed 8 hours ago

Round trip
/
Economy

Mexico City (MEX)to

Quito (UIO)

Oct 07, 2025 - Oct 20, 2025

From

MXN8,149

Viewed 13 hours ago

Round trip
/
Economy

Mexico City (MEX)to

Santiago de Chile (SCL)

Oct 04, 2025 - Oct 10, 2025

From

MXN9,643

Viewed 12 hours ago

Round trip
/
Economy

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Lowest fares from Mexico

From

Mexico City (MEX)to
Panama (PTY)
Oct 01, 2025 - Oct 11, 2025
Round trip
/
Economy

From
MXN5,276*
Viewed 7 hours ago

Mexico City (MEX)to
Caracas (CCS)
Oct 11, 2025 - Oct 18, 2025
Round trip
/
Economy

From
MXN12,383*
Viewed 14 hours ago

Mexico City (MEX)to
Rio de Janeiro (GIG)
Nov 16, 2025 - Nov 24, 2025
Round trip
/
Economy

From
MXN8,977*
Viewed 16 hours ago

Mexico City (MEX)to
Medellin (MDE)
Oct 30, 2025 - Nov 07, 2025
Round trip
/
Economy

From
MXN5,538*
Viewed 14 hours ago

Mexico City (MEX)to
Bogota (BOG)
Oct 06, 2025 - Oct 14, 2025
Round trip
/
Economy

From
MXN4,762*
Viewed 2 hours ago

Mexico City (MEX)to
Cartagena (CTG)
Jan 30, 2026 - Feb 28, 2026
Round trip
/
Economy

From
MXN5,652*
Viewed 4 hours ago

Travel from Mexico

Traveling from Mexico

From Mexico, you can go anywhere on the continent when you travel through the Hub of the Americas® in Panama with Copa Airlines. Whether you’re traveling from Cancun, Mexico City, Guadalajara, Monterrey, or Puerto Vallarta, Copa Airlines connects you to a growing number of destinations in more than 30 countries across the Americas.

Book your travel at copa.com for a worry-free experience. You’ll be able to manage all your travel details in one place. Purchase your ticket, rent a car, buy travel insurance, or arrange ground transportation. Have you heard about our frequent flyer program yet? To earn valuable miles for every trip, join ConnectMiles free of charge and learn about all the benefits it offers.