What is the best fare to fly from Chicago?

The best fare to fly from Chicago starts at **Flights.FromLowestPrice**. Fly with Copa Airlines.

Find Copa Airlines flights from Chicago (ORD) from USD 737*

1 Passenger

Promo Code

From

Departure

Return

Restrictions apply; please see Terms & Conditions.

Offers on flights from Chicago

From

Budget

USD

Chicago (ORD)to

Cartagena (CTG)

Sep 23, 2026 - Sep 28, 2026

From

USD 353

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Bogota (BOG)

Apr 18, 2027 - May 12, 2027

From

USD 393

Viewed 8 hours ago

Round trip

Economy

Chicago (ORD)to

Medellin (MDE)

Oct 05, 2026 - Oct 14, 2026

From

USD 415

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Cali (CLO)

Aug 31, 2026 - Nov 25, 2026

From

USD 450

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Quito (UIO)

Jul 09, 2026 - Jul 13, 2026

From

USD 479

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

San José (SJO)

Aug 08, 2026 - Aug 11, 2026

From

USD 490

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Guayaquil (GYE)

Jul 18, 2026 - Jul 19, 2026

From

USD 510

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Manta (MEC)

Jul 07, 2026 - Aug 10, 2026

From

USD 533

Viewed 17 hours ago

Round trip

Economy

Chicago (ORD)to

Lima (LIM)

Aug 13, 2026 - Aug 17, 2026

From

USD 689

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Panama (PTY)

Feb 20, 2027 - Feb 26, 2027

From

USD 737

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Santa Cruz (VVI)

Mar 22, 2027 - Apr 02, 2027

From

USD 760

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Rio de Janeiro (GIG)

Jul 02, 2026 - Jul 07, 2026

From

USD 763

Viewed 1 day ago

Round trip

Economy

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Best prices on Chicago flights

From

Budget

USD

Chicago (ORD)to

Medellin (MDE)

Oct 05, 2026 - Oct 14, 2026

Round trip

Economy

From

USD 415

Viewed 1 day ago

Chicago (ORD)to

Cali (CLO)

Oct 18, 2026 - Nov 29, 2026

Round trip

Economy

From

USD 450

Viewed 1 day ago

Chicago (ORD)to

Quito (UIO)

Jul 20, 2026 - Jul 26, 2026

Round trip

Economy

From

USD 479

Viewed 23 hours ago

Chicago (ORD)to

Guayaquil (GYE)

Jul 23, 2026 - Jul 26, 2026

Round trip

Economy

From

USD 510

Viewed 1 day ago

Chicago (ORD)to

Lima (LIM)

Jul 27, 2026 - Aug 17, 2026

Round trip

Economy

From

USD 689

Viewed 1 day ago

Chicago (ORD)to

Panama (PTY)

Nov 16, 2026 - Nov 20, 2026

Round trip

Economy

From

USD 737

Viewed 1 day ago

Flights from Chicago with Copa Airlines

When flying from Chicago, Copa Airlines is the best option. Copa airlines offers you a practical and simple way to enjoy your trip without worrying about the little things. Enter the site and manage your flight details, book hotels, and rent cars.

Leaving Chicago’s International Airport

Chicago O'Hare International Airport (ORD) is located 27 km northwest of the center of the city, where it is easily connected to the 24-hour blue line train. For more convenience, you can take a taxi or hire a private shuttle. We offer free Wi-Fi for the first 20 minutes and charging terminals for electronic devices, so you will always be connected. You can also entertain yourself while waiting for your flight by visiting the variety of shops, restaurants, and art exhibitions.

Flying from Chicago with Copa Airlines

Book your flight from Chicago with Copa Airlines and connect to a growing number of destinations across the continent, enjoying a comfortable, timely and safe journey.