What is the best fare to fly from Chicago?

The best fare to fly from Chicago starts at **Flights.FromLowestPrice**. Fly with Copa Airlines.

Find Copa Airlines flights from Chicago (ORD) from USD 592*

1 Passenger

Promo Code

From

Departure

Return

Restrictions apply; please see Terms & Conditions.

Offers on flights from Chicago

From

Budget

USD

Chicago (ORD)to

San José (SJO)

Oct 30, 2026 - Nov 01, 2026

From

USD 386

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Bogota (BOG)

Nov 15, 2026 - Dec 11, 2026

From

USD 453

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Guayaquil (GYE)

Oct 13, 2026 - Oct 20, 2026

From

USD 469

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Medellin (MDE)

Nov 11, 2026 - Dec 01, 2026

From

USD 475

Viewed 21 hours ago

Round trip

Economy

Chicago (ORD)to

Cali (CLO)

Nov 25, 2026 - Dec 02, 2026

From

USD 486

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Quito (UIO)

Nov 16, 2026 - Dec 15, 2026

From

USD 496

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Santa Cruz (VVI)

Nov 06, 2026 - Nov 22, 2026

From

USD 568

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Panama (PTY)

Jan 15, 2027 - Jan 20, 2027

From

USD 592

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Rio de Janeiro (GIG)

Dec 03, 2026 - Dec 11, 2026

From

USD 713

Viewed 7 hours ago

Round trip

Economy

Chicago (ORD)to

Lima (LIM)

Jan 06, 2027 - Apr 07, 2027

From

USD 735

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Caracas (CCS)

Oct 30, 2026 - Nov 11, 2026

From

USD 785

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Buenos Aires (EZE)

Nov 04, 2026 - Nov 12, 2026

From

USD 1,084

Viewed 14 hours ago

Round trip

Economy

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Best prices on Chicago flights

From

Budget

USD

Chicago (ORD)to

Guayaquil (GYE)

Nov 13, 2026 - Nov 20, 2026

Round trip

Economy

From

USD 469

Viewed 1 day ago

Chicago (ORD)to

Medellin (MDE)

Nov 24, 2026 - Dec 01, 2026

Round trip

Economy

From

USD 475

Viewed 17 hours ago

Chicago (ORD)to

Cali (CLO)

Nov 11, 2026 - Nov 20, 2026

Round trip

Economy

From

USD 486

Viewed 1 day ago

Chicago (ORD)to

Quito (UIO)

Oct 28, 2026 - Nov 07, 2026

Round trip

Economy

From

USD 496

Viewed 1 day ago

Chicago (ORD)to

Panama (PTY)

Mar 07, 2027 - Mar 14, 2027

Round trip

Economy

From

USD 592

Viewed 1 day ago

Chicago (ORD)to

Lima (LIM)

Dec 01, 2026 - Dec 22, 2026

Round trip

Economy

From

USD 735

Viewed 1 day ago

Flights from Chicago with Copa Airlines

When flying from Chicago, Copa Airlines is the best option. Copa airlines offers you a practical and simple way to enjoy your trip without worrying about the little things. Enter the site and manage your flight details, book hotels, and rent cars.

Leaving Chicago’s International Airport

Chicago O'Hare International Airport (ORD) is located 27 km northwest of the center of the city, where it is easily connected to the 24-hour blue line train. For more convenience, you can take a taxi or hire a private shuttle. We offer free Wi-Fi for the first 20 minutes and charging terminals for electronic devices, so you will always be connected. You can also entertain yourself while waiting for your flight by visiting the variety of shops, restaurants, and art exhibitions.

Flying from Chicago with Copa Airlines

Book your flight from Chicago with Copa Airlines and connect to a growing number of destinations across the continent, enjoying a comfortable, timely and safe journey.