What is the best fare to fly from Chicago?

The best fare to fly from Chicago starts at **Flights.FromLowestPrice**. Fly with Copa Airlines.

Find Copa Airlines flights from Chicago (ORD) from USD 777*

1 Passenger

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From

Departure

Return

Restrictions apply; please see Terms & Conditions.

Round-trip flights from Chicago

From

Budget

USD

Chicago (ORD)to

Cartagena (CTG)

Nov 14, 2026 - Nov 16, 2026

From

USD 445

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Cali (CLO)

Feb 04, 2027 - Feb 18, 2027

From

USD 469

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Medellin (MDE)

Nov 17, 2026 - Nov 18, 2026

From

USD 487

Viewed 19 hours ago

Round trip

Economy

Chicago (ORD)to

Bogota (BOG)

Nov 14, 2026 - Nov 25, 2026

From

USD 487

Viewed 22 hours ago

Round trip

Economy

Chicago (ORD)to

Pereira (PEI)

Jan 21, 2027 - Jan 26, 2027

From

USD 508

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Guayaquil (GYE)

Jan 10, 2027 - Jan 23, 2027

From

USD 531

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Quito (UIO)

Nov 12, 2026 - Nov 17, 2026

From

USD 557

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Rio de Janeiro (GIG)

Oct 31, 2026 - Nov 06, 2026

From

USD 564

Viewed 4 hours ago

Round trip

Economy

Chicago (ORD)to

Panama (PTY)

Mar 11, 2027 - Mar 15, 2027

From

USD 777

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Sao Paulo (GRU)

Nov 18, 2026 - Nov 24, 2026

From

USD 812

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Lima (LIM)

Nov 14, 2026 - Nov 18, 2026

From

USD 816

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Caracas (CCS)

Feb 08, 2027 - Feb 15, 2027

From

USD 995

Viewed 1 day ago

Round trip

Economy

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Round-trip fares from Chicago

From

Budget

USD

Chicago (ORD)to

Medellin (MDE)

Apr 12, 2027 - Apr 28, 2027

Round trip

Economy

From

USD 508

Viewed 1 day ago

Chicago (ORD)to

Guayaquil (GYE)

Mar 09, 2027 - May 09, 2027

Round trip

Economy

From

USD 531

Viewed 1 day ago

Chicago (ORD)to

Bogota (BOG)

Jan 01, 2027 - Jan 25, 2027

Round trip

Economy

From

USD 532

Viewed 1 day ago

Chicago (ORD)to

Quito (UIO)

Feb 01, 2027 - Feb 15, 2027

Round trip

Economy

From

USD 557

Viewed 1 day ago

Chicago (ORD)to

Panama (PTY)

Mar 11, 2027 - Mar 15, 2027

Round trip

Economy

From

USD 777

Viewed 1 day ago

Chicago (ORD)to

Lima (LIM)

Dec 09, 2026 - Apr 14, 2027

Round trip

Economy

From

USD 816

Viewed 1 day ago

Flights from Chicago with Copa Airlines

When flying from Chicago, Copa Airlines is the best option. Copa airlines offers you a practical and simple way to enjoy your trip without worrying about the little things. Enter the site and manage your flight details, book hotels, and rent cars.

Leaving Chicago’s International Airport

Chicago O'Hare International Airport (ORD) is located 27 km northwest of the center of the city, where it is easily connected to the 24-hour blue line train. For more convenience, you can take a taxi or hire a private shuttle. We offer free Wi-Fi for the first 20 minutes and charging terminals for electronic devices, so you will always be connected. You can also entertain yourself while waiting for your flight by visiting the variety of shops, restaurants, and art exhibitions.

Flying from Chicago with Copa Airlines

Book your flight from Chicago with Copa Airlines and connect to a growing number of destinations across the continent, enjoying a comfortable, timely and safe journey.