What is the best fare to fly from Chicago?

The best fare to fly from Chicago starts at **Flights.FromLowestPrice**. Fly with Copa Airlines.

Find Copa Airlines flights from Chicago (ORD) from USD 687*

1 Passenger

Promo Code

From

Departure

Return

Restrictions apply; please see Terms & Conditions.

Offers on flights from Chicago

From

Budget

USD

Chicago (ORD)to

Cartagena (CTG)

Sep 14, 2026 - Sep 27, 2026

From

USD 333

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

San José (SJO)

Jun 16, 2026 - Jun 20, 2026

From

USD 370

Viewed 23 hours ago

Round trip

Economy

Chicago (ORD)to

Bogota (BOG)

Oct 07, 2026 - Oct 19, 2026

From

USD 373

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Guatemala (GUA)

May 02, 2026 - May 07, 2026

From

USD 391

Viewed 4 hours ago

Round trip

Economy

Chicago (ORD)to

Medellin (MDE)

May 19, 2026 - May 26, 2026

From

USD 405

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Lima (LIM)

May 30, 2026 - Jun 06, 2026

From

USD 408

Viewed 3 hours ago

Round trip

Economy

Chicago (ORD)to

Cali (CLO)

Jun 22, 2026 - Jul 06, 2026

From

USD 434

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Quito (UIO)

Oct 11, 2026 - Nov 16, 2026

From

USD 442

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Guayaquil (GYE)

Sep 12, 2026 - Sep 26, 2026

From

USD 489

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Panama (PTY)

Feb 15, 2027 - Feb 15, 2027

From

USD 687

Viewed 1 day ago

Round trip

Economy

Chicago (ORD)to

Santa Cruz (VVI)

Jun 01, 2026 - Jun 11, 2026

From

USD 703

Viewed 6 hours ago

Round trip

Economy

Chicago (ORD)to

Rio de Janeiro (GIG)

Aug 25, 2026 - Sep 08, 2026

From

USD 712

Viewed 8 hours ago

Round trip

Economy

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Best prices on Chicago flights

From

Budget

USD

Chicago (ORD)to

Bogota (BOG)

Oct 07, 2026 - Oct 19, 2026

Round trip

Economy

From

USD 373

Viewed 1 day ago

Chicago (ORD)to

Medellin (MDE)

Jun 22, 2026 - Jul 13, 2026

Round trip

Economy

From

USD 405

Viewed 1 day ago

Chicago (ORD)to

Lima (LIM)

May 30, 2026 - Jun 06, 2026

Round trip

Economy

From

USD 408

Viewed 3 hours ago

Chicago (ORD)to

Quito (UIO)

Sep 18, 2026 - Oct 02, 2026

Round trip

Economy

From

USD 442

Viewed 1 day ago

Chicago (ORD)to

Guayaquil (GYE)

Aug 26, 2026 - Sep 09, 2026

Round trip

Economy

From

USD 489

Viewed 1 day ago

Chicago (ORD)to

Panama (PTY)

Aug 28, 2026 - Aug 31, 2026

Round trip

Economy

From

USD 687

Viewed 1 day ago

Flights from Chicago with Copa Airlines

When flying from Chicago, Copa Airlines is the best option. Copa airlines offers you a practical and simple way to enjoy your trip without worrying about the little things. Enter the site and manage your flight details, book hotels, and rent cars.

Leaving Chicago’s International Airport

Chicago O'Hare International Airport (ORD) is located 27 km northwest of the center of the city, where it is easily connected to the 24-hour blue line train. For more convenience, you can take a taxi or hire a private shuttle. We offer free Wi-Fi for the first 20 minutes and charging terminals for electronic devices, so you will always be connected. You can also entertain yourself while waiting for your flight by visiting the variety of shops, restaurants, and art exhibitions.

Flying from Chicago with Copa Airlines

Book your flight from Chicago with Copa Airlines and connect to a growing number of destinations across the continent, enjoying a comfortable, timely and safe journey.