What is the best fare to fly from Raleigh?

The best fare to fly from Raleigh starts at **Flights.FromLowestPrice**. Fly with Copa Airlines.

Find Copa Airlines flights from Raleigh (RDU) from USD273*

1 Passenger

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From

Departure

Return

Restrictions apply; please see Terms & Conditions.

Offers on flights from Raleigh

From

Budget

USD

Raleigh (RDU)to

Guatemala (GUA)

Sep 25, 2026 - Oct 02, 2026

From

USD273

Viewed 55 minutes ago

Round trip

Economy

Raleigh (RDU)to

San José (SJO)

May 13, 2026 - May 20, 2026

From

USD300

Viewed 15 hours ago

Round trip

Economy

Raleigh (RDU)to

Guayaquil (GYE)

May 08, 2026 - May 22, 2026

From

USD342

Viewed 4 hours ago

Round trip

Economy

Raleigh (RDU)to

Medellin (MDE)

May 13, 2026 - May 20, 2026

From

USD343

Viewed 21 hours ago

Round trip

Economy

Raleigh (RDU)to

San Salvador (SAL)

May 20, 2026 - May 24, 2026

From

USD349

Viewed 1 day ago

Round trip

Economy

Raleigh (RDU)to

Bogota (BOG)

Nov 06, 2026 - Dec 06, 2026

From

USD353

Viewed 1 day ago

Round trip

Economy

Raleigh (RDU)to

Comayagua, Tegucigalpa (XPL)

Jun 08, 2026 - Jun 29, 2026

From

USD428

Viewed 16 hours ago

Round trip

Economy

Raleigh (RDU)to

Cali (CLO)

Apr 22, 2026 - Apr 26, 2026

From

USD455

Viewed 1 hour ago

Round trip

Economy

Raleigh (RDU)to

Lima (LIM)

Oct 23, 2026 - Oct 26, 2026

From

USD547

Viewed 21 hours ago

Round trip

Economy

Raleigh (RDU)to

Panama (PTY)

Nov 27, 2026 - Dec 02, 2026

From

USD557

Viewed 1 day ago

Round trip

Economy

Raleigh (RDU)to

Pereira (PEI)

Apr 15, 2026 - Apr 19, 2026

From

USD711

Viewed 1 day ago

Round trip

Economy

Raleigh (RDU)to

Sao Paulo (GRU)

Jun 12, 2026 - Jun 15, 2026

From

USD741

Viewed 1 day ago

Round trip

Economy

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Best prices on Raleigh flights

From

Budget

USD

Raleigh (RDU)to

Medellin (MDE)

May 13, 2026 - May 20, 2026

Round trip

Economy

From

USD343

Viewed 21 hours ago

Raleigh (RDU)to

San Salvador (SAL)

May 20, 2026 - May 24, 2026

Round trip

Economy

From

USD349

Viewed 1 day ago

Raleigh (RDU)to

Bogota (BOG)

Aug 28, 2026 - Sep 04, 2026

Round trip

Economy

From

USD353

Viewed 1 day ago

Raleigh (RDU)to

Lima (LIM)

Sep 16, 2026 - Sep 21, 2026

Round trip

Economy

From

USD547

Viewed 16 hours ago

Raleigh (RDU)to

Panama (PTY)

Sep 09, 2026 - Sep 21, 2026

Round trip

Economy

From

USD557

Viewed 1 day ago

Raleigh (RDU)to

Cali (CLO)

May 21, 2026 - May 25, 2026

Round trip

Economy

From

USD592

Viewed 1 day ago

Flights from Raleigh with Copa Airlines

TRAVELING FROM RALEIGH-DURHAM

Get ready to take off to new horizons with flights from Raleigh-Durham! At Copa Airlines, we believe that every flight is an opportunity to explore, discover and connect with the world that awaits you. Our mission is to offer you the best way to get you to exciting destinations throughout the continent directly and efficiently through the Hub of the Americas® at Tocumen International Airport, Panama City.

The freedom to explore is in your hands. Make your reservation at copa.com and discover the ease of managing all the details of your itinerary from a single platform. We're here to inspire you to fly high, connect with new cultures and experience unforgettable adventures in Latin America - get ready to unleash your travel spirit with Copa Airlines!

DEPARTING FROM RALEIGH-DURHAM INTERNATIONAL AIRPORT

Located in the northwest area, a short distance from the city center, Raleigh-Durham International Airport (RDU) offers four weekly flights to and from Panama City. This airport provides excellent accessibility thanks to various transportation alternatives, including buses, trains and private services such as cabs or shuttles, which you can easily coordinate from your accommodation. As you enter the airport, you'll find a variety of options to keep you from getting bored, with art exhibits, restaurants and stores sure to keep you busy while you wait for your flight to depart. Get ready for an unparalleled travel experience from Raleigh-Durham with Copa Airlines!