What is the best fare to fly from Guayaquil?

The best fare to fly from Guayaquil starts at **Flights.FromLowestPrice**. Fly with Copa Airlines.

Find Copa Airlines flights from Guayaquil (GYE) from USD 277*

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Round-trip flights from Guayaquil

From

Budget

USD

Guayaquil (GYE)to

Panama (PTY)

Jan 22, 2027 - Feb 01, 2027

From

USD 277

Viewed 1 day ago

Round trip

Economy

Guayaquil (GYE)to

Cartagena (CTG)

Nov 25, 2026 - Nov 27, 2026

From

USD 303

Viewed 1 day ago

Round trip

Economy

Guayaquil (GYE)to

Miami (MIA)

Jan 18, 2027 - Jan 21, 2027

From

USD 317

Viewed 1 day ago

Round trip

Economy

Guayaquil (GYE)to

Fort Lauderdale (FLL)

Nov 07, 2026 - Nov 17, 2026

From

USD 326

Viewed 1 day ago

Round trip

Economy

Guayaquil (GYE)to

Tampa (TPA)

Dec 01, 2026 - Jan 13, 2027

From

USD 468

Viewed 1 day ago

Round trip

Economy

Guayaquil (GYE)to

Orlando (MCO)

Nov 08, 2026 - Nov 23, 2026

From

USD 480

Viewed 1 day ago

Round trip

Economy

Guayaquil (GYE)to

New York (JFK)

Nov 10, 2026 - Nov 22, 2026

From

USD 521

Viewed 1 day ago

Round trip

Economy

Guayaquil (GYE)to

Punta Cana (PUJ)

Feb 26, 2027 - Mar 10, 2027

From

USD 538

Viewed 1 day ago

Round trip

Economy

Guayaquil (GYE)to

Chicago (ORD)

Oct 30, 2026 - Nov 11, 2026

From

USD 593

Viewed 1 day ago

Round trip

Economy

Guayaquil (GYE)to

Buenos Aires (EZE)

Sep 12, 2027 - Sep 18, 2027

From

USD 667

Viewed 1 day ago

Round trip

Economy

Guayaquil (GYE)to

Rio de Janeiro (GIG)

Mar 14, 2027 - Mar 15, 2027

From

USD 679

Viewed 1 day ago

Round trip

Economy

Guayaquil (GYE)to

Los Angeles (LAX)

Feb 02, 2027 - Feb 18, 2027

From

USD 737

Viewed 1 day ago

Round trip

Economy

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Round-trip fares from Guayaquil

From

Budget

USD

Guayaquil (GYE)to

Panama (PTY)

Jan 22, 2027 - Feb 01, 2027

Round trip

Economy

From

USD 277

Viewed 1 day ago

Guayaquil (GYE)to

Miami (MIA)

Jan 18, 2027 - Jan 21, 2027

Round trip

Economy

From

USD 317

Viewed 1 day ago

Guayaquil (GYE)to

Fort Lauderdale (FLL)

Dec 02, 2026 - Dec 03, 2026

Round trip

Economy

From

USD 326

Viewed 20 hours ago

Guayaquil (GYE)to

Orlando (MCO)

Dec 17, 2026 - Dec 31, 2026

Round trip

Economy

From

USD 480

Viewed 1 day ago

Guayaquil (GYE)to

New York (JFK)

Dec 08, 2026 - Jan 11, 2027

Round trip

Economy

From

USD 521

Viewed 15 hours ago

Guayaquil (GYE)to

Los Angeles (LAX)

Mar 12, 2027 - Mar 20, 2027

Round trip

Economy

From

USD 737

Viewed 1 day ago

Flights from Guayaquil with Copa Airlines

If you want to travel from Guayaquil, book your flight with Copa Airlines to connect with over 70 destinations along America and the Caribbean.

Traveling from the Guayaquil International Airport

The José Joaquín de Olmedo International Airport (GYE) is one of the most renowned in the world. Located 5 kilometers from the center of the city, you can reach it via the Line 2 of the Metrovía. Another option is to take a taxi or a private transport that picks you up from the hotel. Inside the airport you will find banks and currency exchange offices, tax-free craft stores and a variety of cafés and restaurants.

Flying from Guayaquil with Copa Airlines

Copa Airlines offers you an average of four flights from Guayaquil to Panama per day. Book your Guayaquil flights today and remember to visit copa.com to manage your travel details conveniently online.