Find Copa Airlines flights from Guayaquil (GYE) to Santiago de Chile (SCL) from USD578*

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Restrictions apply; please see Terms & Conditions.

Best prices on Guayaquil to Santiago de Chile flights

Apr 2026
FromUSD618*
Viewed 1 day ago
Round trip/Economy
May 2026
FromUSD578*
Viewed 1 day ago
Round trip/Economy
Jun 2026
FromUSD578*
Viewed 9 hours ago
Round trip/Economy
USD578
USD829
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    • FromUSD578-USD829

    *Restrictions apply; please see Terms & Conditions.

    Best airfares from Guayaquil to Santiago de Chile flights

    USD
    Best airfares from Guayaquil to Santiago de Chile flights
    From
    To
    Fare Type
    Dates
    Price
    Guayaquil (GYE)Santiago de Chile (SCL)Round trip
    /
    Economy    		Oct 14, 2026 - Oct 20, 2026

    From

    USD578

    Viewed 1 day ago

    Guayaquil (GYE)Santiago de Chile (SCL)Round trip
    /
    Economy    		May 18, 2026 - May 25, 2026

    From

    USD578

    Viewed 1 day ago

    Guayaquil (GYE)Santiago de Chile (SCL)Round trip
    /
    Economy    		Jun 07, 2026 - Jun 13, 2026

    From

    USD578

    Viewed 1 day ago

    Guayaquil (GYE)Santiago de Chile (SCL)Round trip
    /
    Economy    		Aug 13, 2026 - Aug 26, 2026

    From

    USD578

    Viewed 1 day ago

    Guayaquil (GYE)Santiago de Chile (SCL)Round trip
    /
    Economy    		May 20, 2026 - May 26, 2026

    From

    USD578

    Viewed 1 day ago

    *Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
    *Restrictions apply; please see Terms & Conditions.

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