Find Copa Airlines flights from Guayaquil (GYE) to Santiago de Chile (SCL) from USD337*
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Best prices on Guayaquil to Santiago de Chile flights
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Best airfares from Guayaquil to Santiago de Chile flights
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From | To | Fare Type | Dates | Price |
|---|---|---|---|---|
| Guayaquil (GYE) | Santiago de Chile (SCL) | Round trip / Economy | Nov 10, 2025 - Nov 18, 2025 | From USD337 Viewed 46 minutes ago |
| Guayaquil (GYE) | Santiago de Chile (SCL) | Round trip / Economy | Nov 18, 2025 - Nov 19, 2025 | From USD337 Viewed 17 hours ago |
| Guayaquil (GYE) | Santiago de Chile (SCL) | Round trip / Economy | Sep 10, 2025 - Oct 10, 2025 | From USD337 Viewed 39 minutes ago |
| Guayaquil (GYE) | Santiago de Chile (SCL) | Round trip / Economy | Sep 10, 2025 - Sep 26, 2025 | From USD337 Viewed 2 minutes ago |
| Guayaquil (GYE) | Santiago de Chile (SCL) | Round trip / Economy | Nov 17, 2025 - Nov 19, 2025 | From USD337 Viewed 1 day ago |
*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.
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