Find Copa Airlines flights from Guayaquil (GYE) to Medellin (MDE) from USD273*
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Best prices on Guayaquil to Medellin flights
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Best airfares from Guayaquil to Medellin flights
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From | To | Fare Type | Dates | Price |
|---|---|---|---|---|
| Guayaquil (GYE) | Medellin (MDE) | Round trip / Economy | Jul 05, 2026 - Jul 09, 2026 | From USD273 Viewed 19 hours ago |
| Guayaquil (GYE) | Medellin (MDE) | Round trip / Economy | Dec 21, 2025 - Dec 21, 2025 | From USD288 Viewed 21 hours ago |
| Guayaquil (GYE) | Medellin (MDE) | Round trip / Economy | Dec 19, 2025 - Dec 22, 2025 | From USD288 Viewed 23 hours ago |
| Guayaquil (GYE) | Medellin (MDE) | Round trip / Economy | Dec 25, 2025 - Dec 27, 2025 | From USD288 Viewed 1 day ago |
| Guayaquil (GYE) | Medellin (MDE) | Round trip / Economy | Jan 31, 2026 - Feb 13, 2026 | From USD288 Viewed 1 day ago |
*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.
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