Find Copa Airlines flights from Guayaquil (GYE) to Medellin (MDE) from USD 337*

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Best prices on Guayaquil to Medellin flights

Aug 2026
FromUSD 378*
Viewed 1 day ago
Round trip/Economy
Sep 2026
FromUSD 337*
Viewed 1 day ago
Round trip/Economy
Oct 2026
FromUSD 337*
Viewed 1 day ago
Round trip/Economy
cmp-daily-histogram-bars-legend-min-price-aria-label USD 337
cmp-daily-histogram-bars-legend-max-price-aria-label USD 752
Displaying fares for August-2026
  • GYE–MDE, Aug 27, 2026 – Sep 01, 2026: From USD 378
    27

    Thu

    AUG

  • GYE–MDE, Aug 28, 2026 – Sep 01, 2026: From USD 414
    28

    Fri

  • GYE–MDE, Aug 29, 2026 – Sep 02, 2026: From USD 563
    29

    Sat

  • GYE–MDE: cmp-view-offers-disclaimer. Check availability
    30

    Sun

  • GYE–MDE, Aug 31, 2026 – Sep 07, 2026: From USD 563
    31

    Mon

  • GYE–MDE, Sep 01, 2026 – Sep 08, 2026: From USD 563
    01

    Tue

    SEP

  • GYE–MDE, Sep 02, 2026 – Sep 08, 2026: From USD 563
    02

    Wed

  • GYE–MDE: cmp-view-offers-disclaimer. Check availability
    03

    Thu

  • GYE–MDE, Sep 04, 2026 – Sep 08, 2026: From USD 735
    04

    Fri

  • GYE–MDE, Sep 05, 2026 – Sep 08, 2026: From USD 606
    05

    Sat

  • GYE–MDE, Sep 06, 2026 – Sep 08, 2026: From USD 606
    06

    Sun

  • GYE–MDE, Sep 07, 2026 – Sep 11, 2026: From USD 752
    07

    Mon

  • GYE–MDE, Sep 08, 2026 – Sep 23, 2026: From USD 464
    08

    Tue

  • GYE–MDE, Sep 09, 2026 – Sep 12, 2026: From USD 644
    09

    Wed

  • GYE–MDE, Sep 10, 2026 – Sep 17, 2026: From USD 396
    10

    Thu

  • GYE–MDE, Sep 11, 2026 – Sep 12, 2026: From USD 431
    11

    Fri

  • GYE–MDE, Sep 12, 2026 – Sep 16, 2026: From USD 357
    12

    Sat

  • GYE–MDE, Sep 13, 2026 – Sep 16, 2026: From USD 378
    13

    Sun

  • GYE–MDE, Sep 14, 2026 – Sep 23, 2026: From USD 337
    14

    Mon

  • GYE–MDE: cmp-view-offers-disclaimer. Check availability
    15

    Tue

  • GYE–MDE, Sep 16, 2026 – Sep 23, 2026: From USD 357
    16

    Wed

  • GYE–MDE: cmp-view-offers-disclaimer. Check availability
    17

    Thu

  • GYE–MDE: cmp-view-offers-disclaimer. Check availability
    18

    Fri

  • GYE–MDE: cmp-view-offers-disclaimer. Check availability
    19

    Sat

  • GYE–MDE: cmp-view-offers-disclaimer. Check availability
    20

    Sun

  • GYE–MDE, Sep 21, 2026 – Sep 24, 2026: From USD 337
    21

    Mon

  • GYE–MDE, Sep 22, 2026 – Sep 26, 2026: From USD 337
    22

    Tue

  • GYE–MDE: cmp-view-offers-disclaimer. Check availability
    23

    Wed

  • GYE–MDE, Sep 24, 2026 – Sep 30, 2026: From USD 337
    24

    Thu

  • GYE–MDE, Sep 25, 2026 – Oct 05, 2026: From USD 337
    25

    Fri

  • GYE–MDE, Sep 26, 2026 – Oct 04, 2026: From USD 527
    26

    Sat

    • FromUSD 337-USD 752

    *Restrictions apply; please see Terms & Conditions.

    Best airfares from Guayaquil to Medellin flights

    USD
    Best airfares from Guayaquil to Medellin flights
    From
    To
    Fare Type
    Dates
    Price
    Guayaquil (GYE)Medellin (MDE)Round trip
    /
    Economy    		Oct 21, 2026 - Oct 26, 2026

    From

    USD 337

    Viewed 5 hours ago

    Guayaquil (GYE)Medellin (MDE)Round trip
    /
    Economy    		Sep 21, 2026 - Sep 24, 2026

    From

    USD 337

    Viewed 1 day ago

    Guayaquil (GYE)Medellin (MDE)Round trip
    /
    Economy    		Sep 22, 2026 - Sep 26, 2026

    From

    USD 337

    Viewed 1 day ago

    Guayaquil (GYE)Medellin (MDE)Round trip
    /
    Economy    		May 04, 2027 - May 06, 2027

    From

    USD 337

    Viewed 23 hours ago

    Guayaquil (GYE)Medellin (MDE)Round trip
    /
    Economy    		Oct 23, 2026 - Oct 26, 2026

    From

    USD 337

    Viewed 1 day ago

    *Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
    *Restrictions apply; please see Terms & Conditions.

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