Find Copa Airlines flights from Medellin (MDE) from USD 290*
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Restrictions apply; please see Terms & Conditions.
Offers on flights from Medellin
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USD
Medellin (MDE)to
Panama (PTY)Oct 31, 2026 - Nov 07, 2026
From
USDÂ 290
Viewed 1 day ago
Round trip
Economy
Medellin (MDE)to
Miami (MIA)Sep 01, 2026 - Sep 05, 2026
From
USDÂ 378
Viewed 1 day ago
Round trip
Economy
Medellin (MDE)to
Punta Cana (PUJ)Sep 09, 2026 - Sep 12, 2026
From
USDÂ 392
Viewed 13 hours ago
Round trip
Economy
Medellin (MDE)to
Mexico City (MEX)Aug 20, 2026 - Aug 26, 2026
From
USDÂ 397
Viewed 1 day ago
Round trip
Economy
Medellin (MDE)to
Boston (BOS)Sep 24, 2026 - Oct 14, 2026
From
USDÂ 405
Viewed 1 hour ago
Round trip
Economy
Medellin (MDE)to
Cancun (CUN)Sep 14, 2026 - Sep 20, 2026
From
USDÂ 409
Viewed 23 hours ago
Round trip
Economy
Medellin (MDE)to
Orlando (MCO)Nov 10, 2026 - Nov 16, 2026
From
USDÂ 427
Viewed 1 day ago
Round trip
Economy
Medellin (MDE)to
New York (JFK)May 18, 2027 - May 25, 2027
From
USDÂ 442
Viewed 1 day ago
Round trip
Economy
Medellin (MDE)to
Santiago de Chile (SCL)Aug 28, 2026 - Sep 01, 2026
From
USDÂ 462
Viewed 16 hours ago
Round trip
Economy
Medellin (MDE)to
Sao Paulo (GRU)Aug 24, 2026 - Aug 28, 2026
From
USDÂ 479
Viewed 1 day ago
Round trip
Economy
Medellin (MDE)to
Rio de Janeiro (GIG)Aug 21, 2026 - Aug 26, 2026
From
USDÂ 519
Viewed 1 day ago
Round trip
Economy
Medellin (MDE)to
Los Angeles (LAX)Oct 18, 2026 - Nov 07, 2026
From
USDÂ 523
Viewed 6 hours ago
Round trip
Economy
*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.
Best prices on Medellin flights
flight_takeoff
flight_land
USD
Medellin (MDE)to
Panama (PTY)
Oct 31, 2026 - Nov 07, 2026
Round trip
Economy
From
USDÂ 290
Viewed 1 day ago
Medellin (MDE)to
Miami (MIA)
Sep 01, 2026 - Sep 05, 2026
Round trip
Economy
From
USDÂ 378
Viewed 1 day ago
Medellin (MDE)to
Boston (BOS)
Sep 24, 2026 - Oct 14, 2026
Round trip
Economy
From
USDÂ 405
Viewed 1 hour ago
Medellin (MDE)to
Orlando (MCO)
Sep 26, 2026 - Oct 04, 2026
Round trip
Economy
From
USDÂ 427
Viewed 1 day ago
Medellin (MDE)to
Sao Paulo (GRU)
Sep 12, 2026 - Sep 26, 2026
Round trip
Economy
From
USDÂ 479
Viewed 1 day ago
Medellin (MDE)to
Rio de Janeiro (GIG)
Oct 27, 2026 - Nov 02, 2026
Round trip
Economy
From
USDÂ 519
Viewed 1 day ago
*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.
Flights from Medellin with Copa Airlines
Depart on a flight from Medellin with Copa Airlines and take advantage of the extensive network of destinations we offer, as well as complimentary drinks and the loyalty program of ConnectMiles, ideal for frequent travelers.
The José MarÃa Córdova International Airport
Depart from Medellin at the José MarÃa Córdova International Airport (MDE), which is almost an hour away from the city, so take your precautions when you take your flight. This airport operates 24 hours a day and has three restaurants and a commercial area with banking and bureau de change services. Arrive at the airport by taxi, one of the public service buses leaving the San Diego Mall or a rental car.
Your flight from Medellin with Copa Airlines
We offer more than 70 destinations throughout the continent through the Hub of the Americas in Panama City with daily flights from Medellin.
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