Find Copa Airlines flights from Medellin (MDE) from USD 277*
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Restrictions apply; please see Terms & Conditions.
Offers on flights from Medellin
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USD
Medellin (MDE)to
Panama (PTY)Aug 18, 2026 - Oct 18, 2026
From
USDÂ 277
Viewed 1 day ago
Round trip
Economy
Medellin (MDE)to
San José (SJO)Sep 17, 2026 - Nov 11, 2026
From
USDÂ 294
Viewed 1 day ago
Round trip
Economy
Medellin (MDE)to
Miami (MIA)Sep 28, 2026 - Oct 07, 2026
From
USDÂ 354
Viewed 1 day ago
Round trip
Economy
Medellin (MDE)to
Santiago de Chile (SCL)Sep 23, 2026 - Sep 30, 2026
From
USDÂ 370
Viewed 5 hours ago
Round trip
Economy
Medellin (MDE)to
Mexico City (MEX)Jun 23, 2026 - Jun 29, 2026
From
USDÂ 393
Viewed 1 day ago
Round trip
Economy
Medellin (MDE)to
Punta Cana (PUJ)Aug 13, 2026 - Aug 21, 2026
From
USDÂ 399
Viewed 8 hours ago
Round trip
Economy
Medellin (MDE)to
Cancun (CUN)Oct 20, 2026 - Oct 23, 2026
From
USDÂ 405
Viewed 1 day ago
Round trip
Economy
Medellin (MDE)to
Orlando (MCO)Aug 18, 2026 - Aug 22, 2026
From
USDÂ 411
Viewed 1 day ago
Round trip
Economy
Medellin (MDE)to
New York (JFK)Sep 16, 2026 - Sep 21, 2026
From
USDÂ 434
Viewed 5 hours ago
Round trip
Economy
Medellin (MDE)to
Tampa (TPA)Jun 30, 2026 - Jul 18, 2026
From
USDÂ 444
Viewed 1 day ago
Round trip
Economy
Medellin (MDE)to
Boston (BOS)Jul 22, 2026 - Aug 22, 2026
From
USDÂ 466
Viewed 1 day ago
Round trip
Economy
Medellin (MDE)to
Los Angeles (LAX)Jun 23, 2026 - Jun 24, 2026
From
USDÂ 570
Viewed 1 day ago
Round trip
Economy
*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.
Best prices on Medellin flights
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flight_land
USD
Medellin (MDE)to
Panama (PTY)
Sep 05, 2026 - Sep 09, 2026
Round trip
Economy
From
USDÂ 277
Viewed 1 day ago
Medellin (MDE)to
Miami (MIA)
Sep 28, 2026 - Oct 07, 2026
Round trip
Economy
From
USDÂ 354
Viewed 1 day ago
Medellin (MDE)to
Santiago de Chile (SCL)
Sep 16, 2026 - Sep 30, 2026
Round trip
Economy
From
USDÂ 370
Viewed 7 hours ago
Medellin (MDE)to
Cancun (CUN)
Sep 21, 2026 - Sep 24, 2026
Round trip
Economy
From
USDÂ 405
Viewed 21 hours ago
Medellin (MDE)to
Boston (BOS)
Jul 22, 2026 - Aug 22, 2026
Round trip
Economy
From
USDÂ 466
Viewed 1 day ago
Medellin (MDE)to
Mexico City (MEX)
Jul 15, 2026 - Dec 04, 2026
Round trip
Economy
From
USDÂ 516
Viewed 1 day ago
*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.
Flights from Medellin with Copa Airlines
Depart on a flight from Medellin with Copa Airlines and take advantage of the extensive network of destinations we offer, as well as complimentary drinks and the loyalty program of ConnectMiles, ideal for frequent travelers.
The José MarÃa Córdova International Airport
Depart from Medellin at the José MarÃa Córdova International Airport (MDE), which is almost an hour away from the city, so take your precautions when you take your flight. This airport operates 24 hours a day and has three restaurants and a commercial area with banking and bureau de change services. Arrive at the airport by taxi, one of the public service buses leaving the San Diego Mall or a rental car.
Your flight from Medellin with Copa Airlines
We offer more than 70 destinations throughout the continent through the Hub of the Americas in Panama City with daily flights from Medellin.
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