Find Copa Airlines flights from Medellin (MDE) from USD279*
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Restrictions apply; please see Terms & Conditions.
Offers on flights from Medellin
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USD
Medellin (MDE)to
Panama (PTY)Apr 14, 2026 - Apr 22, 2026
From
USD279
Viewed 1 day ago
Round trip
Economy
Medellin (MDE)to
Miami (MIA)May 15, 2026 - May 27, 2026
From
USD321
Viewed 1 day ago
Round trip
Economy
Medellin (MDE)to
Orlando (MCO)Apr 06, 2026 - May 06, 2026
From
USD334
Viewed 1 day ago
Round trip
Economy
Medellin (MDE)to
Cancun (CUN)Jun 06, 2026 - Jun 14, 2026
From
USD403
Viewed 1 day ago
Round trip
Economy
Medellin (MDE)to
New York (JFK)May 11, 2026 - Aug 24, 2026
From
USD408
Viewed 13 hours ago
Round trip
Economy
Medellin (MDE)to
Boston (BOS)Aug 19, 2026 - Sep 29, 2026
From
USD429
Viewed 1 day ago
Round trip
Economy
Medellin (MDE)to
Santiago de Chile (SCL)Apr 05, 2026 - Apr 15, 2026
From
USD442
Viewed 1 day ago
Round trip
Economy
Medellin (MDE)to
Sao Paulo (GRU)Mar 26, 2026 - Mar 28, 2026
From
USD448
Viewed 19 hours ago
Round trip
Economy
Medellin (MDE)to
Los Angeles (LAX)Apr 22, 2026 - Apr 29, 2026
From
USD484
Viewed 1 day ago
Round trip
Economy
Medellin (MDE)to
Rio de Janeiro (GIG)Jun 12, 2026 - Jun 17, 2026
From
USD491
Viewed 11 hours ago
Round trip
Economy
Medellin (MDE)to
Mexico City (MEX)Aug 11, 2026 - Aug 18, 2026
From
USD517
Viewed 22 hours ago
Round trip
Economy
Medellin (MDE)to
Buenos Aires (EZE)Jun 10, 2026 - Jun 20, 2026
From
USD627
Viewed 1 day ago
Round trip
Economy
*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.
Best prices on Medellin flights
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flight_land
USD
Medellin (MDE)to
Panama (PTY)
Apr 30, 2026 - May 03, 2026
Round trip
Economy
From
USD279
Viewed 1 day ago
Medellin (MDE)to
Miami (MIA)
May 15, 2026 - May 27, 2026
Round trip
Economy
From
USD321
Viewed 1 day ago
Medellin (MDE)to
Orlando (MCO)
May 21, 2026 - May 30, 2026
Round trip
Economy
From
USD334
Viewed 1 day ago
Medellin (MDE)to
Boston (BOS)
Aug 19, 2026 - Sep 29, 2026
Round trip
Economy
From
USD429
Viewed 1 day ago
Medellin (MDE)to
Sao Paulo (GRU)
Apr 30, 2026 - May 25, 2026
Round trip
Economy
From
USD448
Viewed 14 hours ago
Medellin (MDE)to
Santiago de Chile (SCL)
Aug 17, 2026 - Aug 22, 2026
Round trip
Economy
From
USD478
Viewed 1 day ago
*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.
Flights from Medellin with Copa Airlines
Depart on a flight from Medellin with Copa Airlines and take advantage of the extensive network of destinations we offer, as well as complimentary drinks and the loyalty program of ConnectMiles, ideal for frequent travelers.
The José MarÃa Córdova International Airport
Depart from Medellin at the José MarÃa Córdova International Airport (MDE), which is almost an hour away from the city, so take your precautions when you take your flight. This airport operates 24 hours a day and has three restaurants and a commercial area with banking and bureau de change services. Arrive at the airport by taxi, one of the public service buses leaving the San Diego Mall or a rental car.
Your flight from Medellin with Copa Airlines
We offer more than 70 destinations throughout the continent through the Hub of the Americas in Panama City with daily flights from Medellin.
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