What is the best fare to fly from Medellin?

The best fare to fly from Medellin starts at **Flights.FromLowestPrice**. Fly with Copa Airlines.

Find Copa Airlines flights from Medellin (MDE) from USD 342*

1 Passenger

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Restrictions apply; please see Terms & Conditions.

Round-trip flights from Medellin

From

Budget

USD

Medellin (MDE)to

San José (SJO)

Nov 05, 2026 - Nov 10, 2026

From

USD 285

Viewed 1 hour ago

Round trip

Economy

Medellin (MDE)to

Miami (MIA)

Jan 21, 2027 - Jan 23, 2027

From

USD 299

Viewed 1 day ago

Round trip

Economy

Medellin (MDE)to

Panama (PTY)

Dec 18, 2026 - Jan 20, 2027

From

USD 342

Viewed 7 hours ago

Round trip

Economy

Medellin (MDE)to

Punta Cana (PUJ)

Apr 07, 2027 - Apr 10, 2027

From

USD 412

Viewed 1 day ago

Round trip

Economy

Medellin (MDE)to

Cancun (CUN)

Mar 12, 2027 - Mar 16, 2027

From

USD 473

Viewed 1 day ago

Round trip

Economy

Medellin (MDE)to

Mexico City (MEX)

Nov 18, 2026 - Nov 23, 2026

From

USD 478

Viewed 10 hours ago

Round trip

Economy

Medellin (MDE)to

Boston (BOS)

Nov 10, 2026 - Nov 26, 2026

From

USD 518

Viewed 1 day ago

Round trip

Economy

Medellin (MDE)to

Orlando (MCO)

Nov 19, 2026 - Nov 26, 2026

From

USD 524

Viewed 50 minutes ago

Round trip

Economy

Medellin (MDE)to

New York (JFK)

Nov 12, 2026 - Nov 24, 2026

From

USD 538

Viewed 4 hours ago

Round trip

Economy

Medellin (MDE)to

Tampa (TPA)

Dec 05, 2026 - Jan 04, 2027

From

USD 538

Viewed 3 hours ago

Round trip

Economy

Medellin (MDE)to

Rio de Janeiro (GIG)

Nov 09, 2026 - Nov 12, 2026

From

USD 565

Viewed 1 day ago

Round trip

Economy

Medellin (MDE)to

Los Angeles (LAX)

Dec 11, 2026 - Jan 29, 2027

From

USD 568

Viewed 3 hours ago

Round trip

Economy

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

Round-trip fares from Medellin

From

Budget

USD

Medellin (MDE)to

Miami (MIA)

Jan 21, 2027 - Jan 23, 2027

Round trip

Economy

From

USD 299

Viewed 1 day ago

Medellin (MDE)to

Panama (PTY)

Jan 11, 2027 - Jan 19, 2027

Round trip

Economy

From

USD 342

Viewed 9 hours ago

Medellin (MDE)to

Punta Cana (PUJ)

Apr 07, 2027 - Apr 10, 2027

Round trip

Economy

From

USD 412

Viewed 1 day ago

Medellin (MDE)to

Mexico City (MEX)

Mar 12, 2027 - Mar 16, 2027

Round trip

Economy

From

USD 478

Viewed 1 day ago

Medellin (MDE)to

Boston (BOS)

Dec 06, 2026 - Jan 19, 2027

Round trip

Economy

From

USD 518

Viewed 3 hours ago

Medellin (MDE)to

Orlando (MCO)

Feb 25, 2027 - Mar 19, 2027

Round trip

Economy

From

USD 524

Viewed 1 day ago

Flights from Medellin with Copa Airlines

Depart on a flight from Medellin with Copa Airlines and take advantage of the extensive network of destinations we offer, as well as complimentary drinks and the loyalty program of ConnectMiles, ideal for frequent travelers.

The José María Córdova International Airport

Depart from Medellin at the José María Córdova International Airport (MDE), which is almost an hour away from the city, so take your precautions when you take your flight. This airport operates 24 hours a day and has three restaurants and a commercial area with banking and bureau de change services. Arrive at the airport by taxi, one of the public service buses leaving the San Diego Mall or a rental car.