Find Copa Airlines flights from Medellin (MDE) to Guayaquil (GYE) from USD271*
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Best prices on Medellin to Guayaquil flights
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Best airfares from Medellin to Guayaquil flights
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From | To | Fare Type | Dates | Price |
|---|---|---|---|---|
| Medellin (MDE) | Guayaquil (GYE) | Round trip / Economy | Sep 10, 2025 - Sep 27, 2025 | From USD271 Viewed 1 day ago |
| Medellin (MDE) | Guayaquil (GYE) | Round trip / Economy | Sep 09, 2025 - Sep 30, 2025 | From USD271 Viewed 1 day ago |
| Medellin (MDE) | Guayaquil (GYE) | Round trip / Economy | Sep 04, 2025 - Sep 10, 2025 | From USD271 Viewed 1 day ago |
| Medellin (MDE) | Guayaquil (GYE) | Round trip / Economy | Sep 10, 2025 - Sep 30, 2025 | From USD271 Viewed 1 hour ago |
| Medellin (MDE) | Guayaquil (GYE) | Round trip / Economy | Sep 12, 2025 - Sep 20, 2025 | From USD286 Viewed 2 hours ago |
*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.
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