Find Copa Airlines flights from Medellin (MDE) to Santiago de Chile (SCL) from USD395*

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Best prices on Medellin to Santiago de Chile flights

Best airfares from Medellin to Santiago de Chile flights

USD
Best airfares from Medellin to Santiago de Chile flights
From
To
Fare Type
Dates
Price
Medellin (MDE)Santiago de Chile (SCL)Round trip
/
Economy
Nov 13, 2025 - Nov 20, 2025

From

USD395

Viewed 1 day ago

Medellin (MDE)Santiago de Chile (SCL)Round trip
/
Economy
Oct 15, 2025 - Oct 22, 2025

From

USD395

Viewed 1 day ago

Medellin (MDE)Santiago de Chile (SCL)Round trip
/
Economy
Nov 10, 2025 - Feb 09, 2026

From

USD395

Viewed 18 hours ago

Medellin (MDE)Santiago de Chile (SCL)Round trip
/
Economy
Nov 09, 2025 - Nov 23, 2025

From

USD395

Viewed 48 minutes ago

Medellin (MDE)Santiago de Chile (SCL)Round trip
/
Economy
Mar 12, 2026 - Mar 23, 2026

From

USD409

Viewed 6 hours ago

*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.

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