Find Copa Airlines flights from Medellin (MDE) to Santiago de Chile (SCL) from USD 424*

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Best prices on Medellin to Santiago de Chile flights

Apr 2026
FromUSD 424*
Viewed 15 hours ago
Round trip/Economy
May 2026
FromUSD 424*
Viewed 4 hours ago
Round trip/Economy
Jun 2026
No results available
USD 424
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    • FromUSD 424-USD 681

    *Restrictions apply; please see Terms & Conditions.

    Best airfares from Medellin to Santiago de Chile flights

    USD
    Best airfares from Medellin to Santiago de Chile flights
    From
    To
    Fare Type
    Dates
    Price
    Medellin (MDE)Santiago de Chile (SCL)Round trip
    /
    Economy    		May 01, 2026 - May 06, 2026

    From

    USD 424

    Viewed 18 minutes ago

    Medellin (MDE)Santiago de Chile (SCL)Round trip
    /
    Economy    		Apr 24, 2026 - May 04, 2026

    From

    USD 424

    Viewed 1 hour ago

    Medellin (MDE)Santiago de Chile (SCL)Round trip
    /
    Economy    		May 05, 2026 - May 13, 2026

    From

    USD 424

    Viewed 4 hours ago

    Medellin (MDE)Santiago de Chile (SCL)Round trip
    /
    Economy    		Apr 29, 2026 - May 06, 2026

    From

    USD 424

    Viewed 15 hours ago

    Medellin (MDE)Santiago de Chile (SCL)Round trip
    /
    Economy    		Apr 17, 2026 - Jun 10, 2026

    From

    USD 435

    Viewed 1 day ago

    *Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
    *Restrictions apply; please see Terms & Conditions.

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