Find Copa Airlines flights from Medellin (MDE) to San Francisco (SFO) from USD 706*

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Best prices on Medellin to San Francisco flights

Oct 2026
FromUSD 721*
Viewed 1 day ago
Round trip/Economy
Nov 2026
FromUSD 706*
Viewed 1 day ago
Round trip/Economy
Dec 2026
No results available
cmp-daily-histogram-bars-legend-min-price-aria-label USD 721
Displaying fares for October-2026
  • MDE–SFO: cmp-view-offers-disclaimer. Check availability
    11

    Sun

    OCT

  • MDE–SFO: cmp-view-offers-disclaimer. Check availability
    12

    Mon

  • MDE–SFO: cmp-view-offers-disclaimer. Check availability
    13

    Tue

  • MDE–SFO: cmp-view-offers-disclaimer. Check availability
    14

    Wed

  • MDE–SFO, Oct 15, 2026 – Nov 26, 2026: From USD 721
    15

    Thu

  • MDE–SFO: cmp-view-offers-disclaimer. Check availability
    16

    Fri

  • MDE–SFO: cmp-view-offers-disclaimer. Check availability
    17

    Sat

  • MDE–SFO: cmp-view-offers-disclaimer. Check availability
    18

    Sun

  • MDE–SFO: cmp-view-offers-disclaimer. Check availability
    19

    Mon

  • MDE–SFO: cmp-view-offers-disclaimer. Check availability
    20

    Tue

  • MDE–SFO: cmp-view-offers-disclaimer. Check availability
    21

    Wed

  • MDE–SFO: cmp-view-offers-disclaimer. Check availability
    22

    Thu

  • MDE–SFO: cmp-view-offers-disclaimer. Check availability
    23

    Fri

  • MDE–SFO: cmp-view-offers-disclaimer. Check availability
    24

    Sat

  • MDE–SFO: cmp-view-offers-disclaimer. Check availability
    25

    Sun

  • MDE–SFO: cmp-view-offers-disclaimer. Check availability
    26

    Mon

  • MDE–SFO: cmp-view-offers-disclaimer. Check availability
    27

    Tue

  • MDE–SFO: cmp-view-offers-disclaimer. Check availability
    28

    Wed

  • MDE–SFO: cmp-view-offers-disclaimer. Check availability
    29

    Thu

  • MDE–SFO: cmp-view-offers-disclaimer. Check availability
    30

    Fri

  • MDE–SFO: cmp-view-offers-disclaimer. Check availability
    31

    Sat

  • MDE–SFO, Nov 01, 2026 – Nov 27, 2026: From USD 758
    01

    Sun

    NOV

  • MDE–SFO, Nov 02, 2026 – Nov 27, 2026: From USD 743
    02

    Mon

  • MDE–SFO, Nov 03, 2026 – Nov 16, 2026: From USD 801
    03

    Tue

  • MDE–SFO: cmp-view-offers-disclaimer. Check availability
    04

    Wed

  • MDE–SFO: cmp-view-offers-disclaimer. Check availability
    05

    Thu

  • MDE–SFO: cmp-view-offers-disclaimer. Check availability
    06

    Fri

  • MDE–SFO: cmp-view-offers-disclaimer. Check availability
    07

    Sat

  • MDE–SFO: cmp-view-offers-disclaimer. Check availability
    08

    Sun

  • MDE–SFO: cmp-view-offers-disclaimer. Check availability
    09

    Mon

  • MDE–SFO: cmp-view-offers-disclaimer. Check availability
    10

    Tue

    • FromUSD 721-USD 801

    *Restrictions apply; please see Terms & Conditions.

    Best airfares from Medellin to San Francisco flights

    USD
    Best airfares from Medellin to San Francisco flights
    From
    To
    Fare Type
    Dates
    Price
    Medellin (MDE)San Francisco (SFO)Round trip
    /
    Economy    		Nov 27, 2026 - Feb 19, 2027

    From

    USD 706

    Viewed 4 hours ago

    Medellin (MDE)San Francisco (SFO)Round trip
    /
    Economy    		Nov 24, 2026 - Feb 16, 2027

    From

    USD 706

    Viewed 1 day ago

    Medellin (MDE)San Francisco (SFO)Round trip
    /
    Economy    		Oct 15, 2026 - Nov 26, 2026

    From

    USD 721

    Viewed 1 day ago

    Medellin (MDE)San Francisco (SFO)Round trip
    /
    Economy    		Oct 15, 2026 - Nov 27, 2026

    From

    USD 743

    Viewed 1 day ago

    Medellin (MDE)San Francisco (SFO)Round trip
    /
    Economy    		Nov 02, 2026 - Nov 27, 2026

    From

    USD 743

    Viewed 3 hours ago

    *Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
    *Restrictions apply; please see Terms & Conditions.

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